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Totum-448, a polyphenol-rich plant extract, decreases hepatic steatosis and inflammation in diet-induced MASLD mice2025 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Liver Disease Diagnosis and Treatment Open access
Joost M. Lambooij, Vivien Chavanelle, Marie Vallier, Hendrik J.P. van der Zande, Yolanda F. Otero, Frank Otto, +7 more
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Long Non-Coding RNAs in Response to Ebola Virus Vaccine-Induced Immunity2025 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Cancer-related molecular mechanisms research Open access
Izabela Mamede, Thomaz Lüscher Dias, Isabelle Franco Moscardini, Barbara Marinho, Fernando Marcon, Thiago Dominguez Crespo Hirata, +11 more
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The landscape of tertiary lymphoid structures in endometrial cancer revealed through harmonized multi-level transcriptomics2025 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Cancer Immunotherapy and Biomarkers Open access
Marta Requesens, Koen Brummel, Arkajyoti Bhattacharya, Feija Somefun, Nienke van Rooij, Annechien Plat, +10 more
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Rhizosphere microbiome promotes wheat salt tolerance through root lignin biosynthesis2026 Research Square preprint Agricultural and Biological Sciences Plant-Microbe Interactions and Immunity Open access
Guangzhou Wang, Ni Gang, Shiqian Meng, Jiyu Jia, Dapu Zhou, Т. Martijn Bezemer, +4 more
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Same-section spatial metabolo-transcriptomics using Stereo-meta-seq reveals DHA-driven kidney maturation2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Single-cell and spatial transcriptomics Open access
Roan H van Scheppingen, Baihua Wu, Yumeng Zhang, Sytske Schep, Ulli Winter, Fengxiang Wang, +10 more
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WALDO: community-Wide Annotation of γδ Lymphocytes in single-cell Data, Openly benchmarked2026 Zenodo (CERN European Organization for Nuclear Research) preprint Biochemistry, Genetics and Molecular Biology Single-cell and spatial transcriptomics Open access
Farid Keramati, Moosa Rezwani, Likai Tan, David Hamilton, Zheng Song, Tao Yang, +10 more
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Chemoproteomic mapping of active glycan-processing networks in a defined gut microbiome2026 ChemRxiv preprint Biochemistry, Genetics and Molecular Biology Gut microbiota and health Open access
Isabelle B. Pickles, Thamy Lívia Ribeiro Côrrea, Qinnan Yang, Yurong Chen, Zirui Li, Nicole M. Koropatkin, +3 more
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Multicenter self-supervised computational pathology identifies prognostic histomorphological phenotypes in colorectal cancer2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Computer Science AI in cancer detection Open access
Floor Heilijgers, Hortense Le, Nicolas Coudray, Afreen Karimkhan, Derek Chen, Koen C.M.J. Peeters, +3 more
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Comparative human embryo-mapping reveals neural bias of neuromesodermal progenitors in stem cell axial elongation models2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Developmental Biology and Gene Regulation Open access
Yuting Wang, Rafaella Buzatu, Cecile Herbermann, Micha Drukker, Christian J. Schröter
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Methylation-Guided Stratification of Colorectal Cancer Reveals Immune Subtypes with Distinct Clinical Outcomes2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Epigenetics and DNA Methylation
Eiman I. Ahmed, Raghvendra Mall, Christophe Michel Raynaud, Heba Saadeh, Shimaa Sherif, Rania Alanany, +4 more
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O-GlcNAcylation and low glycolysis underpin Th2 polarization by dendritic cells2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Glycosylation and Glycoproteins Research Open access
Leonard R. Pelgrom, Marjolein Quik, José Javier Fernández, Thiago A. Patente, Graham A. Heieis, Alexey Sergushichev, +21 more
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Nuclear Factor I genes drive chondrogenic cell-fate commitment2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Pluripotent Stem Cells Research Open access
Rick Mulders, Mathew Nickel Maunu, Marcella van Hoolwerff, Giorgia Mazzini, Lucas Jansen Klomp, Hil G. E. Meijer, +3 more
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CMAS dampens anti-tumor immunity and associates with response to neoadjuvant immunotherapy in melanoma2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Cancer Immunotherapy and Biomarkers Open access
Magalí B. Coccimiglio, Sofia Ibáñez‐Molero, Babet O. Springer, Laura J. W. Kruijssen, Georgia Clayton, Reece Davison, +17 more
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Cross-presentation of citrullinated antigens drives cytotoxic CD8 + T cell responses in rheumatoid arthritis2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Rheumatoid Arthritis Research and Therapies Open access
Jae‐Seung Moon, Mengrui Zhang, Laura S. van Dam, Eun Kyung Song, Orr Sharpe, Julie Carman, +6 more
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Functionally and epigenetically distinct programs define the heterogeneity of trained immunity2026 Research Square preprint Immunology and Microbiology Immune responses and vaccinations Open access
Mihai Gheorghe Netea, Patricia Vuscan, Qiuyao Zhan, shahin bolori hanafi, Brenda Kischkel, Titus Schlüter, +18 more
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The Deacetylases HDAC1 and HDAC2 Safeguard BCR-ABL-positive Cells from Replication Stress-Induced Apoptosis via the Nuclear to Mitochondrial p73-NOXA Axis2025 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Histone Deacetylase Inhibitors Research
Al‐Hassan M. Mustafa, Miriam Pons, Nisintha Mahendrarajah, Maren Wiegerling, Jörg Hartkamp, Markus Christmann, +4 more
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Multiscale reorganization of brain and behavior under large-scale electrical perturbation2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Neuroscience Functional Brain Connectivity Studies Open access
Sarah Kreuzer, Juergen Dukart, Justine Y. Hansen, Hoang Kim Nguyen, Michael Bentsch, Sophia Zieger, +9 more
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Zygotene cilia regulate meiosis, germ cell development and fertility in zebrafish, mice, and humans2025 Research Square preprint Biochemistry, Genetics and Molecular Biology Genetic and Kidney Cyst Diseases Open access
Yaniv M. Elkouby, Xuelian Sun, Avishag Mytlis, Sylwia M. Czukiewska, Brigite Cabrita, Mengmeng Ge, +16 more
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Usherin in the pineal gland: altered sleep in zebrafish models of Usher syndrome type 2a2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Neuroscience Circadian rhythm and melatonin Open access
Jessie M. Hendricks, Vikash Choudhary, Charles R. Heller, Mel van Gemert, Daniël L. A. H. Hornikx, Sanne Broekman, +14 more
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Distinct colorectal cancer genotypes shape microbial ecosystems and reveal stage-specific microbiota dependencies2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Gut microbiota and health Open access
Valentina Brunner, Nicholas Bodenstein, Antonio Enrico Zaurito, M Silva, Frederic Saab, Fabian Springer, +18 more
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