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Nuclear Factor I genes drive chondrogenic cell-fate commitment2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Pluripotent Stem Cells Research Open access
Rick Mulders, Mathew Nickel Maunu, Marcella van Hoolwerff, Giorgia Mazzini, Lucas Jansen Klomp, Hil G. E. Meijer, +3 more
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CMAS dampens anti-tumor immunity and associates with response to neoadjuvant immunotherapy in melanoma2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Cancer Immunotherapy and Biomarkers Open access
Magalí B. Coccimiglio, Sofia Ibáñez‐Molero, Babet O. Springer, Laura J. W. Kruijssen, Georgia Clayton, Reece Davison, +17 more
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Cross-presentation of citrullinated antigens drives cytotoxic CD8 + T cell responses in rheumatoid arthritis2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Rheumatoid Arthritis Research and Therapies Open access
Jae‐Seung Moon, Mengrui Zhang, Laura S. van Dam, Eun Kyung Song, Orr Sharpe, Julie Carman, +6 more
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Towards biomarkers for outcomes after pancreatic ductal adenocarcinoma and ischemic stroke, with focus on (co-)morbidity and aging / cellular senescence (SASKit): protocol for a prospective cohort study
Larissa Henze, Uwe Walter, Hugo Murua Escobar, Christian Junghanß, Robert Jaster, Rüdiger Köhling, +9 more
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OX40 agonism enhances efficacy of PD-L1 checkpoint blockade by shifting the cytotoxic T cell differentiation spectrum2021 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Cancer Immunotherapy and Biomarkers Open access
Guillaume Beyrend, Tetje Cornelia van der Sluis, Esmé T.I. van der Gracht, Tamim Abdelaal, Simon P. Jochems, Robert A. Belderbos, +16 more
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Cyclin E/CDK2 deficiency links cell cycle control to intestinal barrier integrity and tight junction regulation2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Neuroscience Barrier Structure and Function Studies Open access
Hannes Hatten, Anna M. Verwaayen, Melissa Corcini-Berndt, Emiel P. C. van der Vorst, Daniela Paffen, Yulia Alexandrowna Nevzorova, +3 more
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The Deacetylases HDAC1 and HDAC2 Safeguard BCR-ABL-positive Cells from Replication Stress-Induced Apoptosis via the Nuclear to Mitochondrial p73-NOXA Axis2025 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Histone Deacetylase Inhibitors Research
Al‐Hassan M. Mustafa, Miriam Pons, Nisintha Mahendrarajah, Maren Wiegerling, Jörg Hartkamp, Markus Christmann, +4 more
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Multiscale reorganization of brain and behavior under large-scale electrical perturbation2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Neuroscience Functional Brain Connectivity Studies Open access
Sarah Kreuzer, Juergen Dukart, Justine Y. Hansen, Hoang Kim Nguyen, Michael Bentsch, Sophia Zieger, +9 more
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Inflammatory response in hematopoietic stem and progenitor cells triggered by activating SHP2 mutations evokes blood defects2020 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Protein Tyrosine Phosphatases Open access
Maja Šolman, Sasja Blokzijl-Franke, Florian Piques, Chuan Yan, Qiqi Yang, Marion Strullu, +6 more
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The Brugada syndrome associated gene WT1 impacts on SCN5A expression and cardiac conduction2025 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Cardiac electrophysiology and arrhythmias Open access
E. Madelief Marsman, Joost Allard Offerhaus, Thomas Stervinou, Leander Beekman, Simona Casini, T J Streef, +11 more
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Oncogenic Ras-Src-cortactin signaling rewires actin-generated forces to drive basement membrane rupture and initiate breast cancer invasion2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Cellular Mechanics and Interactions Open access
Eric Platz‐Baudin, Julian Eschenbruch, Yannick Herfs, Georg Dreissen, Ronald Wein, Emiel P. C. van der Vorst, +3 more
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Usherin in the pineal gland: altered sleep in zebrafish models of Usher syndrome type 2a2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Neuroscience Circadian rhythm and melatonin Open access
Jessie M. Hendricks, Vikash Choudhary, Charles R. Heller, Mel van Gemert, Daniël L. A. H. Hornikx, Sanne Broekman, +14 more
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Multimodal Data Integration Advances Longitudinal Prediction of the Naturalistic Course of Depression and Reveals a Multimodal Signature of Disease Chronicity2023 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Treatment of Major Depression Open access
Philippe C. Habets, Rajat Mani Thomas, Yuri Milaneschi, Rick Jansen, René Pool, Wouter J. Peyrot, +4 more
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Distinct colorectal cancer genotypes shape microbial ecosystems and reveal stage-specific microbiota dependencies2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Gut microbiota and health Open access
Valentina Brunner, Nicholas Bodenstein, Antonio Enrico Zaurito, M Silva, Frederic Saab, Fabian Springer, +18 more
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Elevated MPS1 converts the fibrous corona into a source of chromosomal instability in colon cancer2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Microtubule and mitosis dynamics Open access
Ana Pinto-Teixeira, André Oliveira, Gonçalo Gouveia, Ana Sousa, Jessica P Roelands, Marco Grillo, +15 more
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Benchmarking Imputation Methods for Single-Cell RNA Sequencing Data Using Peripheral Blood Mononuclear Cells from Acute Myocardial Infarction Patients0citations
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AtlasOT - The Fused Unbalanced Gromov-Wasserstein for Multimodal Integration of Disease Atlases2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Single-cell and spatial transcriptomics Open access
Kai Peng, Mayra L. Ruiz Tejada Segura, Barthélémy Caron, Christoph Kuppe, James Shiniti Nagai, Ivan G. Costa
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T-cell distribution in the dorsal root ganglion across species, sex, and age2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Pain Mechanisms and Treatments Open access
Jayden A. O'Brien, Nishka Kuttanna, Khadijah Mazhar, Marisol Mancilla Moreno, Asta Arendt-Tranholm, Joseph B. Lesnak, +12 more
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Plasmodium falciparum SET10 is a histone H3 lysine K18 methyltransferase that participates in a chromatin modulation network crucial for intraerythrocytic development2024 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Malaria Research and Control Open access
Jean-Pierre Musabyimana, Sherihan Musa, Janice Manti, Ute Distler, Stefan Tenzer, Che Julius Ngwa, +1 more
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