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Enhanced in vivo and ex vivo thrombin generation after lower-leg trauma, but not after knee arthroscopy2023 Thrombosis Journal article Medicine Venous Thromboembolism Diagnosis and Management Open access
Carolina E. Touw, Banne Nemeth, Raymond A. van Adrichem, Astrid van Hylckama Vlieg, Rob G. H. H. Nelissen, Ton Lisman, +1 more
2citations -
Thrombin in complex with dabigatran can still interact with PAR‐1 via exosite‐I and instigate loss of vascular integrity2022 Journal of Thrombosis and Haemostasis article Medicine Blood Coagulation and Thrombosis Mechanisms Open access
Sophie Dólleman, Stijn M. Agten, Henri M.H. Spronk, Tilman M. Hackeng, Mettine H.A. Bos, Henri H. Versteeg, +2 more
15citations -
Sufficient Thrombin Generation Despite 95% Hemodilution: An In Vitro Experimental Study2020 Journal of Clinical Medicine article Medicine Trauma, Hemostasis, Coagulopathy, Resuscitation Open access
Johannes Gratz, Christoph J. Schlimp, Markus Honickel, Nadine Hochhausen, Herbert Schöchl, Oliver Grottke
22citations -
Associations of coagulation parameters and thrombin generation potential with the incidence of type 2 diabetes: mediating role of glycoprotein acetylation2024 European Journal of Epidemiology article Medicine Blood Coagulation and Thrombosis Mechanisms Open access
Jihee Han, Astrid van Hylckama Vlieg, Renée de Mutsert, Frits Richard Rosendaal, Jeroen Hpm van der Velde, Sebastiaan C. Boone, +3 more
8citations -
D‐dimer, thrombin generation, and risk of a first venous thrombosis in the elderly2021 Research and Practice in Thrombosis and Haemostasis article Medicine Venous Thromboembolism Diagnosis and Management Open access
Huijie Wang, Frits Richard Rosendaal, Mary Cushman, Astrid van Hylckama Vlieg
19citations -
In patients with hemophilia, a decreased thrombin generation profile is associated with a severe bleeding phenotype2023 Research and Practice in Thrombosis and Haemostasis article Medicine Hemophilia Treatment and Research Open access
Marieke J.A. Verhagen, Waander L. van Heerde, Johanna G. van der Bom, Erik A.M. Beckers, Nicole M. A. Blijlevens, Michiel Coppens, +6 more
22citations -
Thrombin generation profiling in rare coagulation factor deficiencies: associations with bleeding severity and potential for screening2025 Journal of Thrombosis and Haemostasis article Medicine Blood Coagulation and Thrombosis Mechanisms Open access
Bauke Haisma, Sanna R. Rijpma, Marjon H. Cnossen, Paul L. den Exter, Ilmar C. Kruis, Karina Meijer, +6 more
1citations -
Enhanced thrombin and plasmin generation profiles in alpha-2-antiplasmin–deficient patients: Data from the Rare Bleeding disorders in the Netherlands study2024 Research and Practice in Thrombosis and Haemostasis article Medicine Blood Coagulation and Thrombosis Mechanisms Open access
Bauke Haisma, Sanna R. Rijpma, Marjon H. Cnossen, Paul L. den Exter, Ilmar C. Kruis, Karina Meijer, +6 more
1citations -
Acetyl-CoA Carboxylase Inhibitor CP640.186 Increases Tubulin Acetylation and Impairs Thrombin-Induced Platelet Aggregation2021 International Journal of Molecular Sciences article Medicine Platelet Disorders and Treatments Open access
Marie Octave, Laurence Pirotton, Audrey Ginion, Valentine Robaux, Sophie Lepropre, Jérôme Ambroise, +7 more
10citations -
Recurrent venous thromboembolism: association with thrombin generation and d-dimer2026 Research and Practice in Thrombosis and Haemostasis article Medicine Venous Thromboembolism Diagnosis and Management Open access
Eugenia Biguzzi, Kristien Winckers, Tilman M. Hackeng, Frits Richard Rosendaal, Astrid van Hylckama Vlieg
0citations -
Activation of the Catalytic Activity of Thrombin for Fibrin Formation by Ultrasound2021 Angewandte Chemie International Edition article Biochemistry, Genetics and Molecular Biology Advanced biosensing and bioanalysis techniques Open access
Pengkun Zhao, Shuaidong Huo, Jilin Fan, Junlin Chen, Fabian M. Kiessling, Arnold J. Boersma, +1 more
81citations -
pH and Thrombin Concentration Are Decisive in Synthesizing Stiff, Stable, and Open‐Porous Fibrin‐Collagen Hydrogel Blends without Chemical Cross‐Linker2022 Advanced Healthcare Materials article Biochemistry, Genetics and Molecular Biology Hydrogels: synthesis, properties, applications Open access
Mattis Wachendörfer, Eva Miriam Buhl, Ghazi Ben Messaoud, Walter H. Richtering, Horst Fischer
22citations -
Aktivierung der katalytischen Aktivität von Thrombin für die Bildung von Fibrin durch Ultraschall2021 Angewandte Chemie article Biochemistry, Genetics and Molecular Biology Advanced biosensing and bioanalysis techniques Open access
Pengkun Zhao, Shuaidong Huo, Jilin Fan, Junlin Chen, Fabian M. Kiessling, Arnold J. Boersma, +1 more
2citations -
Size‐Dependent Ultrasound Activation of Thrombin Catalytic Activity by Mechano‐Nanoswitches2025 Advanced Science article Biochemistry, Genetics and Molecular Biology Advanced biosensing and bioanalysis techniques Open access
Zhihuan Liao, Junliang Chen, Jiangting Zeng, Xiangfu Du, Zihao Teng, Johannes Hahmann, +1 more
3citations -
Feasibility to infer accurate fibrinogen concentrations from thrombin generation, prothrombin time, or Reptilase time waveforms2025 Research and Practice in Thrombosis and Haemostasis article Medicine Blood properties and coagulation Open access
Ryanne A. Arisz, Bart Bakker, René van den Ham, Aamer B. Ahmed, Jeroen C.J. Eikenboom, Saskia E.M. Schols, +1 more
1citations -
Individualized anticoagulation monitoring in critically ill patients: study protocol for a prospective observational comparison of Anti-Xa, viscoelastic testing, and thrombin generation2026 Frontiers in Medicine article Medicine Venous Thromboembolism Diagnosis and Management Open access
Martin Mirus, Sebastian Scholz, Adrian Schmidt, Paul Leon Petrick, Oliver Grottke, Peter Markus Spieth, +1 more
0citations