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On the Impact of Basic Mutation Operators and Populations within Evolutionary Algorithms for the Dynamic Weighted Traveling Salesperson Problem1citations
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Breast cancer genomes from CHEK2 c.1100delC mutation carriers lack somatic TP53 mutations and display a unique structural variant size distribution profile2023 Breast Cancer Research article Biochemistry, Genetics and Molecular Biology BRCA gene mutations in cancer Open access
Marcel Smid, Marjanka K. Schmidt, Wendy J. C. Prager‐van der Smissen, Kirsten Ruigrok-Ritstier, Maartje A. C. Schreurs, Sten Cornelissen, +8 more
10citations -
The Prism-Net Search Space Representation for Multi-objective Building Spatial Design2023 Lecture notes in computer science conference-paper Engineering Architecture and Computational Design Open access
Ksenia Pereverdieva, Michael Emmerich, Andre H. Deutz, Tessa Ezendam, Thomas Bäck, Hèrm Hofmeyer
4citations -
Multiple Mutations—A Genetic Marker for Extracapsular Spread in Human Papillomavirus/p16‐Positive Oropharyngeal Carcinoma2025 Laryngoscope Investigative Otolaryngology article Medicine Head and Neck Cancer Studies Open access
Raphaela Graessle, Iris Piwonski, Cora C. Husemann, Karsten Kleo, Deema Sabtan, Achim M. Franzen, +4 more
2citations -
Activating mutations in JAK2 and CALR differentially affect intracellular calcium flux in store operated calcium entry2024 Cell Communication and Signaling article Medicine Myeloproliferative Neoplasms: Diagnosis and Treatment Open access
Vikas Bhuria, Tobias J. Franz, Conny K. Baldauf, Martin Böttcher, Nicolas Chatain, Steffen Koschmieder, +5 more
18citations -
Generation and initial characterization of novel tumour organoid models to study human pancreatic cancer‐induced cachexia2020 Journal of Cachexia Sarcopenia and Muscle article Medicine Nutrition and Health in Aging Open access
Rianne D.W. Vaes, David P.J. van Dijk, Tessa T.J. Welbers, Marinus J. Blok, Merel R. Aberle, Lara Rosaline Heij, +3 more
48citations -
Intra-tumoral genomic heterogeneity in rectal cancer: mutational status is dependent on preoperative biopsy depth and location.2020 Research Square preprint Biochemistry, Genetics and Molecular Biology Cancer Genomics and Diagnostics Open access
Floris A. Vuijk, Carlijn van de Water, Shannon van Lent - van Vliet, Maxime J.M. van der Valk, Femke Simmer, Cornelis J.�H. van de Velde, +3 more
0citations -
Benchmarking artificial intelligence methods for end-to-end computational pathology2021 bioRxiv (Cold Spring Harbor Laboratory) preprint Computer Science AI in cancer detection Open access
Narmin Ghaffari Laleh, Hannah Sophie Muti, Chiara Maria Lavinia Loeffler, Amelie Echle, Oliver Lester Saldanha, Faisal Mahmood, +17 more
15citations -
DrugEx v2: de novo design of drug molecules by Pareto-based multi-objective reinforcement learning in polypharmacology2021 Journal of Cheminformatics article Computer Science Computational Drug Discovery Methods Open access cited by 1 patent
Xuhan Liu, Kai Ye, Herman van Vlijmen, Michael Emmerich, Adriaan P. IJzerman, Gerard J. P. van Westen
118citations