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Deletion of mTOR in liver epithelial cells enhances hepatic metastasis of colon cancer2021 The Journal of Pathology article Biochemistry, Genetics and Molecular Biology PI3K/AKT/mTOR signaling in cancer Open access
Long R. Jiao, Roman Eickhoff, Sandra Jumpertz, Merve Erdem, Andreas Kroh, Hans Duimel, +7 more
7citations -
Models of KPTN-related disorder implicate mTOR signalling in cognitive and overgrowth phenotypes2023 Brain article Biochemistry, Genetics and Molecular Biology Genetics and Neurodevelopmental Disorders Open access
Maria O. Levitin, Lettie E. Rawlins, Gabriela Sánchez-Andrade, Osama A. Arshad, Stephan C. Collins, Stephen J. Sawiak, +35 more
12citations -
Mouse and cellular models of KPTN -related disorder implicate mTOR signalling in cognitive and progressive overgrowth phenotypes2022 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Genetics and Neurodevelopmental Disorders Open access
Maria O. Levitin, Lettie E. Rawlins, Gabriela Sánchez-Andrade, Osama A. Arshad, Stephan C. Collins, Stephen J. Sawiak, +35 more
1citations -
Multi-omics analyses of cancer-linked clinical salmonellae reveal bacterial-induced host metabolic shift and mTOR-dependent cell transformation2024 Cell Reports article Agricultural and Biological Sciences Salmonella and Campylobacter epidemiology Open access
Virginie Stévenin, Claudia E. Coipan, Janneke W. Duijster, Daphne M. van Elsland, Linda Voogd, Lise Bigey, +8 more
5citations -
Enhanced inflammatory response mediated by parenchymal cells associates with resistance towards mTOR inhibition2020 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology PI3K/AKT/mTOR signaling in cancer Open access
Long R. Jiao, Roman Eickhoff, Sandra Jumpertz, Merve Erdem, Andreas Kroh, Hans Duimel, +6 more
0citations -
Hepatocellular loss of mTOR aggravates tumor burden in nonalcoholic steatohepatitis-related HCC2023 Neoplasia article Biochemistry, Genetics and Molecular Biology PI3K/AKT/mTOR signaling in cancer Open access
Andreas Kroh, Jeanette Walter, Athanassios Fragoulis, Diana Möckel, Twan Lammers, Fabian M. Kiessling, +10 more
8citations -
Non-apoptotic FAS signaling controls mTOR activation and extrafollicular maturation in human B cells2024 Science Immunology article Immunology and Microbiology T-cell and B-cell Immunology Open access
Julian Staniek, Geoffroy Andrieux, Melanie Boerries, Iga Janowska, Manuel Fuentes, Paula Díez, +37 more
25citations -
Simultaneous targeting of AMPK and mTOR is a novel therapeutic strategy against prostate cancer2024 Cancer Letters article Biochemistry, Genetics and Molecular Biology PI3K/AKT/mTOR signaling in cancer Open access
Gangyin Zhao, Gabriel Forn‐Cuní, Marvin Scheers, Pier Pieterszoon Lindenbergh, Jie Yin, Quint C. van Loosen, +3 more
22citations -
Simultaneous targeting of AMPK and mTOR is a novel therapeutic strategy against prostate cancer2023 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology PI3K/AKT/mTOR signaling in cancer Open access
Gangyin Zhao, Gabriel Forn‐Cuní, Marvin Scheers, Pier Pieterszoon Lindenbergh, Jie Yin, Quint C. van Loosen, +3 more
2citations -
MYC is a clinically significant driver of mTOR inhibitor resistance in breast cancer2023 The Journal of Experimental Medicine article Biochemistry, Genetics and Molecular Biology PI3K/AKT/mTOR signaling in cancer Open access
Jinhyuk Bhin, Julia Yemelyanenko, Xue Chao, Sjoerd Klarenbeek, Mark Opdam, Yuval Malka, +18 more
26citations -
mTor inhibitor GDC-0349 improves ASO induced SAMMSON knock down resulting in enhanced anti-tumor efficacy in uveal melanoma2020 Ghent University Academic Bibliography (Ghent University) conference-paper Medicine Ocular Oncology and Treatments Open access
Shanna Dewaele, Boél De Paepe, Louis Delhaye, Eric de Bony de Lavergne, Jilke De Wilde, Katrien Vanderheyden, +12 more
0citations -
mTOR Inhibition Is Most Beneficial After Liver Transplantation for Hepatocellular Carcinoma in Patients With Active Tumors2020 Annals of Surgery article Medicine Hepatocellular Carcinoma Treatment and Prognosis Open access
Andreas Anton Schnitzbauer, Natalie Filmann, René A. Adam, Philippe Bachellier, Wolf O. Bechstein, Thomas Becker, +41 more
140citations -
Personalized Medicine Approach in a DCM Patient with LMNA Mutation Reveals Dysregulation of mTOR Signaling2022 Journal of Personalized Medicine article Medicine Cardiomyopathy and Myosin Studies Open access
Balram Neupane, Kabita Pradhan, Audrey Ortega-Ramírez, Parwez Aidery, Vytautas Kučikas, Matthias Marks, +6 more
11citations -
Leucine Reconstitutes Phagocytosis-Induced Cell Death in E. coli-Infected Neonatal Monocytes—Effects on Energy Metabolism and mTOR Signaling2021 International Journal of Molecular Sciences article Biochemistry, Genetics and Molecular Biology Cell death mechanisms and regulation Open access
Stephan Dreschers, Kim Ohl, Julia Möllmann, Klaus Tenbrock, Thorsten W Orlikowsky
5citations -
German longevity study reveals novel rare pro-longevity alleles clustering in mTOR signaling pathway2025 GeroScience article Biochemistry, Genetics and Molecular Biology Genetics, Aging, and Longevity in Model Organisms Open access
Daniel Kolbe, Janina Dose, Pasquale C. Putter, Malte Ziemann, Matthias Laudes, P. Eline Slagboom, +3 more
4citations -
The sodium‐glucose co‐transporter‐2 inhibitor ertugliflozin modifies the signature of cardiac substrate metabolism and reduces cardiac mTOR signalling, endoplasmic reticulum stress and apoptosis
Julia Moellmann, Pascal A. Mann, Ben Arpad Kappel, Florian Kahles, Barbara M. Klinkhammer, Peter Boor, +5 more
52citations -
2,8-Dihydroxyadenine-induced nephropathy causes hexosylceramide accumulation with increased mTOR signaling, reduced levels of protective SirT3 expression and impaired renal mitochondrial function2023 Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease article Medicine Chronic Kidney Disease and Diabetes Open access
Julia Moellmann, Katja Krueger, Dickson W.L. Wong, Barbara M. Klinkhammer, Eva Miriam Buhl, Jonas Dehairs, +7 more
19citations -
ESMO-ESTRO consensus statements on the safety of combining radiotherapy with CDK4/6, HER2, PARP, or mTOR inhibitors2025 Radiotherapy and Oncology article Physics and Astronomy Advanced Radiotherapy Techniques Open access
Evert S.M. van Aken, Ajeet Kumar Gandhi, Sean Michael O'Cathail, Gerben Borst, Jorge Barriuso, Emmanouil Fokas, +26 more
7citations -
Hepatocellular Loss of Mtor Aggravates Tumor Burden in Nonalcoholic Steatohepatitis-Related Hcc2023 SSRN Electronic Journal preprint Biochemistry, Genetics and Molecular Biology PI3K/AKT/mTOR signaling in cancer Open access
Andreas Kroh, Jeanette Walter, Athanassios Fragoulis, Diana Möckel, Twan Lammers, Fabian M. Kiessling, +10 more
0citations -
SPNS1 variants cause multiorgan disease and implicate lysophospholipid transport as critical for mTOR-regulated lipid homeostasis2025 Journal of Clinical Investigation article Biochemistry, Genetics and Molecular Biology Lipid metabolism and biosynthesis Open access
Mei Ding, Michaela Chocholoušková, Cheen Fei Chin, Martin Engvall, Helena Malmgren, Matias Wagner, +10 more
7citations -
Corrigendum: Dual-mTOR Inhibitor Rapalink-1 Reduces Prostate Cancer Patient-Derived Xenograft Growth and Alters Tumor Heterogeneity2021 Frontiers in Oncology erratum Biochemistry, Genetics and Molecular Biology PI3K/AKT/mTOR signaling in cancer Open access
Federico La Manna, Marta De Menna, Nikhil M. Patel, Sofia Karkampouna, Maria Rosaria De Filippo, Irena Klima, +6 more
1citations -
Tsc1 haploinsufficiency leads to Pax2 dysregulation in the developing murine cerebellum2021 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Tuberous Sclerosis Complex Research Open access
Ines Serra, Ana Stravs, Catarina Osório, Maria Roa Oyaga, Martijn Schonewille, Christian Tudorache, +1 more
0citations