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1,6- epi -Cyclophellitol Cyclosulfamidate Is a Bona Fide Lysosomal α-Glucosidase Stabilizer for the Treatment of Pompe Disease2022 Journal of the American Chemical Society article Chemistry Carbohydrate Chemistry and Synthesis Open access
Ken Kok, C.J. Kuo, Rebecca E. Katzy, Lindsey T. Lelieveld, Liang Wu, V. Roig-Zamboni, +7 more
23citations -
Conformational and Electronic Variations in 1,2‐ and 1,5a‐Cyclophellitols and their Impact on Retaining α‐Glucosidase Inhibition2024 Chemistry - A European Journal article Chemistry Carbohydrate Chemistry and Synthesis Open access
Tim P. Ofman, Jurriaan J. A. Heming, Alba Nin‐Hill, Florian Küllmer, E. J. MORAN, Roy Steneker, +11 more
4citations -
Synthesis and Biological Evaluation of Deoxycyclophellitols as Human Retaining β‐Glucosidase Inhibitors2024 Chemistry - A European Journal article Chemistry Carbohydrate Chemistry and Synthesis Open access
Yevhenii Radchenko, Qin Su, Sybrin P. Schröder, Luke van Gijlswijk, Marta Artola, Johannes M. F. G. Aerts, +2 more
3citations -
Mechanism-based heparanase inhibitors reduce cancer metastasis in vivo2022 Proceedings of the National Academy of Sciences article Biochemistry, Genetics and Molecular Biology Proteoglycans and glycosaminoglycans research Open access
Casper de Boer, Zachary Armstrong, Vincent A. J. Lit, Uri Barash, Gijs Ruijgrok, Ilanit Boyango, +12 more
48citations -
From Mechanism-Based Retaining Glycosidase Inhibitors to Activity-Based Glycosidase Profiling2024 Journal of the American Chemical Society article Chemistry Carbohydrate Chemistry and Synthesis Open access
Marta Artola, Johannes M. F. G. Aerts, Gijsbert A. van der Marel, Carme Rovira, Jeroen D. C. Codée, G.J. Davies, +1 more
26citations -
Design and Synthesis of Exocyclic Cyclitol Aziridines as Potential Mechanism‐Based Glycosidase Inactivators2023 European Journal of Organic Chemistry article Chemistry Carbohydrate Chemistry and Synthesis Open access
Tim P. Ofman, Gijsbert A. van der Marel, Jeroen D. C. Codée, Herman S. Overkleeft
4citations -
Rational Design of Mechanism-Based Inhibitors and Activity-Based Probes for the Identification of Retaining α- l -Arabinofuranosidases2020 Journal of the American Chemical Society article Chemistry Carbohydrate Chemistry and Synthesis Open access
Nicholas G. S. McGregor, Marta Artola, Alba Nin‐Hill, Daniël Linzel, Mireille Haon, Jos Reijngoud, +9 more
50citations -
Bespoke Activity-Based Probes Reveal that the Pseudomonas aeruginosa Endoglycosidase, PslG, Is an Endo-β-glucanase2025 Journal of the American Chemical Society article Biochemistry, Genetics and Molecular Biology Bacterial biofilms and quorum sensing Open access
Gijs Ruijgrok, Wendy A. Offen, Isabelle B. Pickles, Deepa Raju, Thanasis Patsos, Casper de Boer, +13 more
7citations -
Oseltamivir aziridines are potent influenza neuraminidase inhibitors and imaging agents2026 Proceedings of the National Academy of Sciences article Medicine Influenza Virus Research Studies Open access
Merijn B. L. Vriends, E. J. MORAN, Martín Calvelo, Thomas Ross Hansen, Isabelle B. Pickles, Xincheng Xin, +17 more
2citations -
Manno- epi -cyclophellitols Enable Activity-Based Protein Profiling of Human α-Mannosidases and Discovery of New Golgi Mannosidase II Inhibitors2020 Journal of the American Chemical Society article Chemistry Carbohydrate Chemistry and Synthesis Open access
Zachary Armstrong, C.J. Kuo, D. Lahav, Rachel D. Johnson, Thomas J. M. Beenakker, Casper de Boer, +14 more
47citations -
Cysteine Nucleophiles in Glycosidase Catalysis: Application of a Covalent β‐ l‐ Arabinofuranosidase Inhibitor2021 Angewandte Chemie International Edition article Chemistry Carbohydrate Chemistry and Synthesis Open access
Nicholas G. S. McGregor, Joan Coines, Valentina Borlandelli, Satoko Amaki, Marta Artola, Alba Nin‐Hill, +11 more
25citations -
Development of Non‐Hydrolysable Oligosaccharide Activity‐Based Inactivators for Endoglycanases: A Case Study on α‐1,6 Mannanases2021 Chemistry - A European Journal article Chemistry Carbohydrate Chemistry and Synthesis Open access
Sybrin P. Schröder, Wendy A. Offen, Alexandra Males, Yi Jin, Casper de Boer, Jacopo Enotarpi, +6 more
5citations -
Detection of Sulfoquinovosidase Activity in Cell Lysates Using Activity‐Based Probes2024 Angewandte Chemie International Edition article Chemistry Carbohydrate Chemistry and Synthesis Open access
Zirui Li, Isabelle B. Pickles, Mahima Sharma, Benjamin Melling, Luise Pallasdies, Jeroen D. C. Codée, +3 more
3citations -
Activity-Based Protein Profiling of Retaining α-Amylases in Complex Biological Samples2021 Journal of the American Chemical Society article Chemistry Carbohydrate Chemistry and Synthesis Open access cited by 3 patents
Yurong Chen, Zachary Armstrong, Marta Artola, Bogdan I. Florea, C.J. Kuo, Casper de Boer, +7 more
31citations -
Synthesis of broad-specificity activity-based probes for exo -β-mannosidases2021 Organic & Biomolecular Chemistry article Chemistry Carbohydrate Chemistry and Synthesis Open access
Nicholas G. S. McGregor, C.J. Kuo, Thomas J. M. Beenakker, Chun-Sing Wong, Wendy A. Offen, Zachary Armstrong, +5 more
14citations -
Structure of a GH51 α- L -arabinofuranosidase from Meripilus giganteus: conserved substrate recognition from bacteria to fungi2020 Acta Crystallographica Section D Structural Biology article Materials Science Enzyme Structure and Function Open access
Nicholas G. S. McGregor, J.P. Turkenburg, Kristian B. R. M. Krogh, Jens Erik Nielsen, Marta Artola, Keith A. Stubbs, +2 more
14citations