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Tofacitinib for ulcerative colitis: results of the prospective Dutch Initiative on Crohn and Colitis (ICC) registry2020 Alimentary Pharmacology & Therapeutics article Biochemistry, Genetics and Molecular Biology Inflammatory Bowel Disease Open access
Vince B. C. Biemans, Jasmijn A M Sleutjes, Annemarie Charlotte de Vries, Alexander G L Bodelier, Gerard D. H. Dijkstra, Bas Oldenburg, +14 more
88citations -
Filgotinib Is an Effective and Safe Treatment Option for Difficult‐To‐Treat Ulcerative Colitis: Real‐World Evidence of the Dutch Initiative on Crohn and Colitis (ICC) Registry2025 United European Gastroenterology Journal article Biochemistry, Genetics and Molecular Biology Inflammatory Bowel Disease Open access
Myrthe R Naber, Andrea E. van der Meulen‐de Jong, Philip W. Voorneveld, Suzanne H. C. Veltkamp, Adriaan A. van Bodegraven, Alexander G L Bodelier, +10 more
3citations -
Tofacitinib fails to prevent T cell transfer colitis in mice but ameliorates disease activity2023 Scientific Reports article Biochemistry, Genetics and Molecular Biology Inflammatory Bowel Disease Open access
Sudheendra Hebbar Subramanyam, Judit Turyne Hriczko, Angeliki Pappas, Angela Schippers, Kim Ohl, Klaus Tenbrock
3citations -
Tofacitinib fails to prevent T cell transfer colitis in mice but ameliorates disease activity2022 Research Square preprint Biochemistry, Genetics and Molecular Biology Inflammatory Bowel Disease Open access
Sudheendra Hebbar Subramanyam, Judit Turyne Hrcziko, Angeliki Pappas, Angela Schippers, Kim Ohl, Klaus Tenbrock
0citations -
MTG16 regulates colonic epithelial differentiation, colitis, and tumorigenesis by repressing E protein transcription factors2022 JCI Insight article Biochemistry, Genetics and Molecular Biology Inflammatory Bowel Disease Open access
Rachel E. Brown, Justin Jacobse, Shruti A. Anant, Koral M. Blunt, Bob Chen, Paige N. Vega, +14 more
16citations -
MTG16 (CBFA2T3) regulates colonic epithelial differentiation, colitis, and tumorigenesis by repressing E protein transcription factors2021 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Inflammatory Bowel Disease Open access
Rachel E. Brown, Justin Jacobse, Shruti A. Anant, Koral M. Blunt, Bob Chen, Paige N. Vega, +14 more
2citations -
Microbial enzymes induce colitis by reactivating triclosan in the mouse gastrointestinal tract2022 Nature Communications article Biochemistry, Genetics and Molecular Biology Gut microbiota and health Open access
Jianan Zhang, Morgan E. Walker, Katherine Z. Sanidad, Hongna Zhang, Yanshan Liang, Ermin Zhao, +25 more
113citations -
P020 Mapping the changing intercellular communication and its downstream effect in Ulcerative Colitis2021 Journal of Crohn s and Colitis conference-abstract Biochemistry, Genetics and Molecular Biology Inflammatory Bowel Disease Open access
Lejla Potari-Gul, Dezső Módos, Dénes Türei, Alberto Valdeolivas, Matthew Madgwick, Julio Sáez-Rodríguez, +1 more
0citations -
DOP75 Effectiveness and Safety of tofacitinib versus vedolizumab in Patients with Ulcerative Colitis; A Nationwide, ICC Registry study2022 Journal of Crohn s and Colitis conference-abstract Biochemistry, Genetics and Molecular Biology Inflammatory Bowel Disease Open access
Tessa Straatmijer, Marijn Caroline Visschedijk, Frank Hoentjen, Ad A. van Bodegraven, Alexander G L Bodelier, Nanne K.H. de Boer, +15 more
0citations -
Withdrawal and Re-treatment with Filgotinib in Ulcerative Colitis: Post Hoc Analyses of the Phase 2b/3 SELECTION and SELECTIONLTE Studies2023 Journal of Crohn s and Colitis article Biochemistry, Genetics and Molecular Biology Inflammatory Bowel Disease Open access
Severine A.R.A. Vermeire, Brian G. Feagan, Laurent Peyrin‐Biroulet, Alessandra Faria Oortwijn, Margaux Faes, Angela de Haas, +1 more
7citations -
OP35 Efficacy and safety outcomes up to ~4 years of treatment with filgotinib 200 mg among patients with Ulcerative Colitis: Results from the SELECTIONLTE study2023 Journal of Crohn s and Colitis conference-abstract Biochemistry, Genetics and Molecular Biology Inflammatory Bowel Disease Open access
B G Feagan, Gerhard Rogler, Margaux Faes, Alessandra Faria Oortwijn, C Rudolph, Laurent Peyrin‐Biroulet
3citations -
P923 Haematological abnormalities during treatment with Janus kinase inhibitors in patients with Ulcerative Colitis: a post hoc analysis2024 Journal of Crohn s and Colitis conference-abstract Biochemistry, Genetics and Molecular Biology Inflammatory Bowel Disease Open access
Roberta Loveikyte, Philip W. Voorneveld, Gerard D. H. Dijkstra, Andrea E. van der Meulen‐de Jong
1citations -
P688 Patient preferences in medication to treat Ulcerative Colitis: a discrete choice experiment2023 Journal of Crohn s and Colitis conference-abstract Biochemistry, Genetics and Molecular Biology Inflammatory Bowel Disease Open access
Tessa Straatmijer, M. Elske van den Akker‐van Marle, Daniëlle van der Horst, Menne PM. Scherpenzeel, Marjolijn Duijvestein
1citations -
DOP58 Tofacitinib for ulcerative colitis: Results of the ICC Registry, a nationwide prospective observational cohort study2020 Journal of Crohn s and Colitis conference-abstract Biochemistry, Genetics and Molecular Biology Inflammatory Bowel Disease Open access
Vince B. C. Biemans, Jasmijn A M Sleutjes, Annemarie Charlotte de Vries, Alexander G L Bodelier, Gerard D. H. Dijkstra, Bas Oldenburg, +13 more
0citations -
P0953 Real world effectiveness and safety of filgotinib in Ulcerative Colitis: 1 year follow-up results of the ICC registry2025 Journal of Crohn s and Colitis conference-abstract Biochemistry, Genetics and Molecular Biology Inflammatory Bowel Disease Open access
Philip W. Voorneveld, Adriaan A. van Bodegraven, Marjolijn Duijvestein, Marieke J. Pierik, Alexander G L Bodelier, Dianne Gelien Bouwknegt, +8 more
0citations -
P0957 Proteomic discordance with clinical and biochemical response filgotinib in Ulcerative Colitis suggests residual inflammatory signals2026 Journal of Crohn s and Colitis conference-abstract Biochemistry, Genetics and Molecular Biology Inflammatory Bowel Disease Open access
Jonas M. Louwers, Suzanne H. C. Veltkamp, Philip W. Voorneveld, Marjolijn Duijvestein, A E Van der Meulen - de Jong, Femke van Wijk, +1 more
0citations -
P1081 Effectiveness of JAK inhibitors in JAK naïve Ulcerative Colitis patients: Comparative analysis of tofacitinib, filgotinib and upadacitinib in the Dutch ICC Registry2026 Journal of Crohn s and Colitis conference-abstract Biochemistry, Genetics and Molecular Biology Inflammatory Bowel Disease Open access
Myrthe R Naber, Dianne Gelien Bouwknegt, Marijn Caroline Visschedijk, L Lourens, A E Van der Meulen - de Jong, Alexander G L Bodelier, +18 more
0citations -
Proton pump inhibitors and gut microbiota dysbiosis: insights into the pathogenesis of ulcerative colitis2025 Frontiers in Microbiology article Biochemistry, Genetics and Molecular Biology Gut microbiota and health Open access
Feng Cao, Shuo Liu, Yanwei Liu, Yong Xin Qi, Yunsheng Cheng, Yong Wang, +1 more
7citations -
Superior Effectiveness of Tofacitinib Compared to Vedolizumab in Anti-TNF-experienced Ulcerative Colitis Patients: A Nationwide Dutch Registry Study2022 Clinical Gastroenterology and Hepatology article Biochemistry, Genetics and Molecular Biology Inflammatory Bowel Disease Open access
Tessa Straatmijer, Vince B. C. Biemans, Marijn Caroline Visschedijk, Frank Hoentjen, Annemarie de Vries, Adriaan A. van Bodegraven, +47 more
51citations -
Effectiveness and safety of tofacitinib for ulcerative colitis: two‐year results of the ICC Registry2022 Alimentary Pharmacology & Therapeutics article Biochemistry, Genetics and Molecular Biology Inflammatory Bowel Disease Open access
Tessa Straatmijer, Fiona D M van Schaik, Alexander G L Bodelier, Marijn Caroline Visschedijk, Annemarie Charlotte de Vries, Cyriel Y. Ponsioen, +13 more
28citations -
O21 Long-term efficacy and safety of filgotinib 200 mg in ulcerative colitis: 5-year interim data from SELECTIONLTE2025 Oral Presentations conference-paper Biochemistry, Genetics and Molecular Biology Inflammatory Bowel Disease Open access
Ian D. Arnott, Brian G. Feagan, Katsuyoshi Matsuoka, Gerhard Rogler, David Laharie, Severine A.R.A. Vermeire, +9 more
0citations -
Soluble mucosal addressin cell adhesion molecule 1 is a biomarker for pediatric ulcerative colitis2026 Molecular and Cellular Pediatrics article Biochemistry, Genetics and Molecular Biology Inflammatory Bowel Disease Open access
Moritz Muschaweck, Christian Gutbier, Gernot Sellge, Angeliki Pappa, Tobias G. Wenzl, Karim Hamesch, +2 more
0citations