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Bioprocess in‐line monitoring using Raman spectroscopy and Indirect Hard Modeling (IHM): A simple calibration yields a robust model2023 Biotechnology and Bioengineering article Chemistry Spectroscopy and Chemometric Analyses Open access
David Heinrich Müller, Carsten Flake, Thorsten Brands, Hans‐Jürgen Koß
17citations -
Process Model Files for Manuscript under Consideration "Techno-Economic Modeling and Optimization of a Lignocellulosic Biorefinery for gamma-Valerolactone and 1,4-Pentanediol Production"2026 Zenodo (CERN European Organization for Nuclear Research) dataset Engineering Biofuel production and bioconversion Open access
Kaan Rehwasser, Julian Nöhl, Alexander Walter Wilhelm Echtermeyer, Lukas Polte, Andreas Jupke, Pascal Albrecht, +3 more
0citations -
Process Model Files for Manuscript under Consideration "Techno-Economic Modeling and Optimization of a Lignocellulosic Biorefinery for gamma-Valerolactone and 1,4-Pentanediol Production"2026 Zenodo (CERN European Organization for Nuclear Research) dataset Engineering Biofuel production and bioconversion Open access
Kaan Rehwasser, Julian Nöhl, Alexander Walter Wilhelm Echtermeyer, Lukas Polte, Andreas Jupke, Pascal Albrecht, +3 more
0citations -
COMPmodelpy: Understanding Microbial Metabolism in Bioreactors in a Compartment Modeling Framework2026 RWTH Publications (RWTH Aachen) conference-paper Biochemistry, Genetics and Molecular Biology Microbial Metabolic Engineering and Bioproduction Open access
Samira van den Bogaard, Titania Insani Sugiarto, Tobias B. Alter, Lars M. Blank
0citations -
COMPmodelpy: Understanding Microbial Metabolism in Bioreactors in a Compartment Modeling Framework2026 Zenodo (CERN European Organization for Nuclear Research) article Biochemistry, Genetics and Molecular Biology Microbial Metabolic Engineering and Bioproduction Open access
Samira van den Bogaard, Titania Insani Sugiarto, Tobias B. Alter, Lars M. Blank
0citations -
Control of parallelized bioreactors II: probabilistic quantification of carboxylic acid reductase activity for bioprocess optimization2022 Bioprocess and Biosystems Engineering article Biochemistry, Genetics and Molecular Biology Microbial Metabolic Engineering and Bioproduction Open access
Nikolas von den Eichen, Michael Osthege, Lukas Bromig, Wolfgang Wiechert, Marco Oldiges, Dirk Weuster‐Botz
11citations -
Synthetic spectral libraries for Raman model calibration2025 Analytical and Bioanalytical Chemistry article Chemistry Spectroscopy and Chemometric Analyses Open access cited by 1 patent
Louis Hellequin, Vicent J. Borràs, Patrick Romann, Nandita Vishwanathan, Jonathan Souquet, Thomas K. Villiger
3citations -
Explore or exploit? A model‐based screening strategy for PETase secretion by Corynebacterium glutamicum2022 Biotechnology and Bioengineering article Biochemistry, Genetics and Molecular Biology Enzyme Production and Characterization Open access
Laura M. Helleckes, Carolin Müller, Tim Griesbach, Vera Waffenschmidt, Matthias Moch, Michael Osthege, +2 more
22citations -
Assessing the capabilities of 2D fluorescence monitoring in microtiter plates with data-driven modeling for secondary substrate limitation experiments of Hansenula polymorpha2023 Journal of Biological Engineering article Chemistry Spectroscopy and Chemometric Analyses Open access
Christoph Berg, Laura Herbst, Lisa Gremm, Nina Ihling, Olivier Paquet‐Durand, Bernd Hitzmann, +1 more
3citations -
Computer-Aided Bioprocess and Solvent Design for Industrial Methyl Ketone Production2026 ChemRxiv preprint Biochemistry, Genetics and Molecular Biology Microbial Metabolic Engineering and Bioproduction Open access
Henry Hilker, Lukas Raßpe-Lange, Lukas Polte, Anita L. Ziegler, Clemens Kortmann, Alexander Mitsos, +2 more
0citations -
Computer-aided bioprocess and solvent design for industrial methyl ketone production2026 Chemical Engineering Journal article Biochemistry, Genetics and Molecular Biology Microbial Metabolic Engineering and Bioproduction Open access
Henry Hilker, Lukas Raßpe-Lange, Lukas Polte, Anita L. Ziegler, Clemens Kortmann, Alexander Mitsos, +2 more
0citations -
Analysis across scales: Integrated insights in metabolism and economic feasibility of recombinant protein production from CO2 and H20citations
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Analysis across scales: Integrated insights in metabolism and economic feasibility of recombinant protein production from CO2 and H20citations
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Communities of Niche-optimized Strains (CoNoS) – Design and creation of stable, genome-reduced co-cultures2022 Metabolic Engineering article Biochemistry, Genetics and Molecular Biology Microbial Metabolic Engineering and Bioproduction Open access
Simone Schito, Rico Zuchowski, Daniel Bergen, Daniel Strohmeier, Bastian Wollenhaupt, Philipp Menke, +7 more
19citations