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Acidosis-mediated increase in IFN-γ-induced PD-L1 expression on cancer cells as an immune escape mechanism in solid tumors2023 Molecular Cancer article Medicine Cancer Immunotherapy and Biomarkers Open access cited by 1 patent
Philipp Knopf, Dimitri Stowbur, Sabrina H. L. Hoffmann, Natalie Hermann, Andreas Maurer, Valentina Bucher, +23 more
88citations -
Tumor mutational load, CD8+ T cells, expression of PD-L1 and HLA class I to guide immunotherapy decisions in NSCLC patients2020 Cancer Immunology Immunotherapy article Medicine Cancer Immunotherapy and Biomarkers Open access cited by 1 patent
Daan P. Hurkmans, Merian E. Kuipers, Ronald van Marion, Ron H.J. Mathijssen, Piet E. Postmus, Pieter Sicco Hiemstra, +3 more
96citations -
Bidirectional crosstalk between epithelial-mesenchymal plasticity and IFNγ-induced PD-L1 expression promotes tumor progression2022 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Cancer Cells and Metastasis Open access
Gerhard A. Burger, Daphne Nesenberend, Carlijn M. Lems, Sander C. Hille, Joost B. Beltman
1citations -
Intradermal immunization with Plasmodium berghei late-arresting genetically attenuated sporozoites induces PD-L1 expression on regulatory macrophages and dendritic cells
Roos van Schuijlenburg, Chanel Milène Naar, Helena M. de Bes-Roeleveld, Severine C. Chevalley-Maurel, Lili A. Zigó, Emma L. Houlder, +4 more
0citations -
155eP Real-world effectiveness of first-line nivolumab plus ipilimumab with chemotherapy in patients with non-small cell lung cancer with low PD-L1 tumor expression (Dutch NVALT-34 study)
Corina van den Hurk, B.J.M. Peters, Dagmar T A Hiensch, E.F. Smit, E.A. Kastelijn, B.V. van Veggel, +4 more
0citations -
IFN‐γ‐induced PD‐L1 expression on human melanocytes is impaired in vitiligo2021 Experimental Dermatology article Biochemistry, Genetics and Molecular Biology melanin and skin pigmentation Open access
Marcella Willemsen, Gabrielle Krebbers, Esther P.M. Tjin, Karin J. Willemsen, Alesha Louis, Veronique A. L. Konijn, +6 more
22citations -
Tolerability and efficacy of the cancer vaccine UV1 in patients with recurrent or metastatic PD-L1 positive head and neck squamous cell carcinoma planned for first-line treatment with pembrolizumab – the randomized phase 2 FOCUS trial
Anna Paula Brandt, Christoph Schultheiß, Konrad Friedrich Klinghammer, Philippe Schafhausen, Chia‐Jung Busch, Markus Blaurock, +8 more
11citations -
293 Acidosis promotes immune escape through the IFN-γ-induced induction of PD-L1 transcription in cancer cells2023 Journal of Investigative Dermatology article Medicine Cancer Immunotherapy and Biomarkers Open access
Dimitri Stowbur, P. Knopf, S. Hoffmann, V. Buchner, M. Poxleitner, I. Gonzalez-Menendez, +11 more
0citations -
CRISPR activation screening identifies VGLL3 and GATA2 as transcriptional regulators of PD-L12021 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Cancer Immunotherapy and Biomarkers Open access
Ruud H. M. Wijdeven, Birol Cabukusta, Xueer Qiu, Daniel Borràs, Yun Liang, Jacques Neefjes
0citations