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Healthy volunteers in first‐in‐human oncology drug development for small molecules2021 British Journal of Clinical Pharmacology article Mathematics Statistical Methods in Clinical Trials Open access
Begoña de las Heras, Dalila Bouyoucef‐Cherchalli, Lesley Reeve, Andreas Reichl, Debra Mandarino, Stephen D. Flach, +3 more
18citations -
Accelerating vaccine trial conduct in a pandemic with a hot spot‐based inclusion strategy using trial and epidemic simulation2021 Clinical and Translational Science article Mathematics Statistical Methods in Clinical Trials Open access
Johan L. van der Plas, Michiel Joost van Esdonk, Ingrid M. C. Kamerling, Adam F. Cohen
7citations -
Sentinel dosing: A proposed algorithm to guide decision making on which cohorts in early phase clinical pharmacology trials should use this approach2025 British Journal of Clinical Pharmacology article Mathematics Statistical Methods in Clinical Trials Open access
Jules A. A. C. Heuberger, Perry de Jongh, Ewoud‐Jan van Hoogdalem, Wim J. Tamminga, Pieter de Graeff, Geert Jan Groeneveld
4citations -
Dose escalations in phase I studies: Feasibility of interpreting blinded pharmacodynamic data2022 British Journal of Clinical Pharmacology article Mathematics Statistical Methods in Clinical Trials Open access
Gerardus J. Hassing, Michiel Joost van Esdonk, Gerard J. P. van Westen, Adam F. Cohen, Jacobus Burggraaf, Pim Gal
2citations -
Quantification of the pharmacokinetic-toxicodynamic relationship of oral docetaxel co-administered with ritonavir2020 Investigational New Drugs article Mathematics Statistical Methods in Clinical Trials Open access
Huixin Yu, Julie M. Janssen, Vincent A. de Weger, Bastiaan Nuijen, Rik Stuurman, Serena Marchetti, +4 more
1citations
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