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Strong vaccine responses during chemotherapy are associated with prolonged cancer survival2020 Science Translational Medicine article Immunology and Microbiology Immunotherapy and Immune Responses Open access cited by 2 patents
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Reactive oxygen species as an initiator of toxic innate immune responses in retort to SARS-CoV-2 in an ageing population, consider N-acetylcysteine as early therapeutic intervention2020 Toxicology Reports article Medicine COVID-19 Clinical Research Studies Open access cited by 1 patent
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ISA101 and nivolumab for HPV-16 + cancer: updated clinical efficacy and immune correlates of response2022 Journal for ImmunoTherapy of Cancer article Medicine Cancer Immunotherapy and Biomarkers Open access
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A third vaccination with a single T cell epitope confers protection in a murine model of SARS-CoV-2 infection2022 Nature Communications article Medicine SARS-CoV-2 and COVID-19 Research Open access cited by 2 patents
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Peptide emulsions in incomplete Freund’s adjuvant create effective nurseries promoting egress of systemic CD4+ and CD8+ T cells for immunotherapy of cancer2022 Journal for ImmunoTherapy of Cancer article Immunology and Microbiology Immunotherapy and Immune Responses Open access cited by 2 patents
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Intradermal vaccination of HPV-16 E6 synthetic peptides conjugated to an optimized Toll-like receptor 2 ligand shows safety and potent T cell immunogenicity in patients with HPV-16 positive (pre-)malignant lesions2022 Journal for ImmunoTherapy of Cancer article Immunology and Microbiology Immunotherapy and Immune Responses Open access
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IFN‐γ‐induced PD‐L1 expression on human melanocytes is impaired in vitiligo2021 Experimental Dermatology article Biochemistry, Genetics and Molecular Biology melanin and skin pigmentation Open access
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Design of TLR2-ligand-synthetic long peptide conjugates for therapeutic vaccination of chronic HBV patients2020 Antiviral Research article Immunology and Microbiology Immunotherapy and Immune Responses Open access
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Results of a randomized, double-blind, placebo-controlled, phase 2 study (OpcemISA) of the combination of ISA101b and cemiplimab versus cemiplimab for recurrent/metastatic (R/M) HPV16-positive oropharyngeal cancer (OPC).2024 Journal of Clinical Oncology conference-abstract Medicine Head and Neck Cancer Studies Open access
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Induction of broad multifunctional CD8+ and CD4+ T cells by hepatitis B virus antigen-based synthetic long peptides ex vivo2023 Frontiers in Immunology article Medicine Hepatitis B Virus Studies Open access cited by 1 patent
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Enhanced HPV16 E6/E7+ tumor eradication via induction of tumor-specific T cells by therapeutic vaccination with virosomes presenting synthetic long peptides2023 Cancer Immunology Immunotherapy article Immunology and Microbiology Immunotherapy and Immune Responses Open access
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Delayed vaccine-induced CD8+ T cell expansion by topoisomerase I inhibition mediates enhanced CD70-dependent tumor eradication2023 Journal for ImmunoTherapy of Cancer article Immunology and Microbiology Immunotherapy and Immune Responses Open access
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Combination immunotherapy with synthetic long peptides and chemotherapy or PD-1 blocker for cancers caused by human papilloma virus type 162023 Seminars in Immunopathology article Immunology and Microbiology Immunotherapy and Immune Responses
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878P Final results of a phase II study of peltopepimut-S and cemiplimab in patients with relapsed/metastatic HPV16+ oropharyngeal cancer that progressed with prior anti-PD-1 therapy
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