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Papers matching “human” 46

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From mice to clinical relevance: humanizing neuroscience with human-based model systems
2026 Frontiers in Cellular Neuroscience article Veterinary Animal testing and alternatives Open access

Aniella Bak, Karen M. J. van Loo, Deborah Kronenberg‐Versteeg, Henner Koch

0

citations
Human relevance of in vivo and in vitro skin irritation tests for hazard classification of pesticides
2024 Cutaneous and Ocular Toxicology article Veterinary Animal testing and alternatives Open access

Hans Raabe, Gertrude‐Emilia Costin, David Allen, Anna Lowit, Marco Corvaro, Julie Breeden-Alemi, +6 more

14

citations
Improving Translation by Identifying Evidence for More Human-Relevant Preclinical Strategies
2020 Animals article Veterinary Animal testing and alternatives Open access

Merel Ritskes‐Hoitinga, Cathalijn H. C. Leenaars, Wouter Beumer, Tineke Coenen-de Roo, Frans R. Stafleu, Franck L. B. Meijboom

28

citations
New approach methodologies in human regulatory toxicology – Not if, but how and when!
2023 Environment International article Veterinary Animal testing and alternatives Open access

Sebastian Schmeisser, Andrea Miccoli, Martin von Bergen�, Elisabet Berggren, Albert Braeuning, Wibke Busch, +23 more

381

citations
Assessing the transferability and reproducibility of 3D in vitro liver models from primary human multi-cellular microtissues to cell-line based HepG2 spheroids
2022 Toxicology in Vitro article Veterinary Animal testing and alternatives Open access

Samantha V. Llewellyn, Ali Kermanizadeh, Victor Chibueze Ude, Nicklas Raun Jacobsen, Gillian E. Conway, Ume-Kulsoom Shah, +8 more

11

citations
OS02-05 3D human intestinal organoids as a platform to assess compound-induced gastrointestinal toxicity
2026 Toxicology Letters article Veterinary Animal testing and alternatives

T. Martianez, C. Demeester, T. Cholewinski, Melissa C. Zuiderwijk, B. Amiri, Christian Maaß, +4 more

0

citations
Advancing transcriptomics-based mechanistic assessment of nephrotoxicity in vitro using the human RPTEC/TERT1 TXG-MAPr gene co-expression network
2025 Toxicological Sciences article Veterinary Animal testing and alternatives Open access

Hugo W van Kessel, Steven J. Kunnen, Giulia Callegaro, Bob van de Water

2

citations
Advancing transcriptomics-based mechanistic assessment of nephrotoxicity in vitro using the human RPTEC/TERT1 TXG-MAPr gene co-expression network
2025 Leiden Repository (Leiden University) article Veterinary Animal testing and alternatives Open access

0

citations
Next-generation risk assessment of chemicals – Rolling out a human-centric testing strategy to drive 3R implementation: The RISK-HUNT3R project perspective
2022 ALTEX article Veterinary Animal testing and alternatives Open access

Giorgia Pallocca

64

citations
Assessment of the utility of the novel Phenion® full thickness human skin model for detecting the skin irritation potential of antimicrobial cleaning products
2023 Toxicology in Vitro article Veterinary Animal testing and alternatives Open access

Kathryn E. Page, Walter M. A. Westerink, Kristie M. Sullivan, Thomas S. McDonald, Clive S. Roper

11

citations
Applicability of NAMs to support a read-across based hazard assessment workflow for systemic toxicity: a conazole case study
2026 Archives of Toxicology article Veterinary Animal testing and alternatives Open access

Barira Islam, Jenny Irwan, Lukas Wijaya, Bas ter Braak, Amer Jamalpoor, Tamara Meijer, +26 more

0

citations
Application of AOPs to assist regulatory assessment of chemical risks – Case studies, needs and recommendations
2022 Environmental Research article Veterinary Animal testing and alternatives Open access

Lola Bajard, Ondřej Adamovský, Karine Audouze, Kirsten A. Baken, Robert Barouki, Joost B. Beltman, +28 more

102

citations
Translatability of preclinical to early clinical tolerable and pharmacologically active dose ranges for central nervous system active drugs
2023 Translational Psychiatry article Veterinary Animal testing and alternatives Open access

Guilherme S. Ferreira, Francis M. Dijkstra, Désirée H. Veening-Griffioen, Wouter Boon, Huub Schellekens, Ellen H.M. Moors, +3 more

8

citations
Review of dose setting for the extended one-generation reproductive toxicity studies (OECD TG 443): Considerations on ECHA's dose level selection recommendations
2024 Regulatory Toxicology and Pharmacology article Veterinary Animal testing and alternatives Open access

Manon E. W. Beekhuijzen, Jason C. Manton, Pragati Sawhney Coder, Katy O. Goyak, Rashin Ghaffari, Susan L. Makris, +3 more

9

citations
Shedding of Brucella melitensis happens through milk macrophages in the murine model of infection
2020 Scientific Reports article Veterinary Brucella: diagnosis, epidemiology, treatment Open access

Wiebke Jansen, Aurore M. Demars, Charles Nicaise, Jacques Godfroid, Xavier De Bolle, Angeline Reboul, +1 more

16

citations
Animal models and animal-free innovations for cardiovascular research: current status and routes to be explored. Consensus document of the ESC Working Group on Myocardial Function and the ESC Working Group on Cellular Biology of the Heart
2022 Cardiovascular Research article Veterinary Animal testing and alternatives Open access

Lucie Carrier, Thomas Eschenhagen, Larissa Fabritz, Mariann Gyöngyösi, Jean‐Sébastien Hulot, Silvia Giuliana Priori

90

citations
Integrate mechanistic evidence from new approach methodologies (NAMs) into a read-across assessment to characterise trends in shared mode of action
2021 Toxicology in Vitro article Veterinary Animal testing and alternatives Open access

Sylvia E. Escher, Alejandro Aguayo‐Orozco, Emilio Benfenati, Annette Bitsch, Thomas A. Braunbeck, Katharina Brotzmann, +26 more

39

citations
Animal-free Safety Assessment of Chemicals: Project Cluster for Implementation of Novel Strategies (ASPIS) definition of new approach methodologies
2025 Environmental Toxicology and Chemistry article Veterinary Animal testing and alternatives Open access

John Kenneth Colbourne, Sylvia E. Escher, Robert Lee, Mathieu Vinken, Bob van de Water, Jonathan H. Freedman

11

citations
Refining humane endpoint detection by time-series forecasting and threshold definition using a multivariate severity score
2026 Frontiers in Physiology article Veterinary Animal testing and alternatives Open access

Sara Lutscher, Lisa Goral, Christine Häger, Anna Munk, Miriam Heider, Nora Weegh, +5 more

0

citations
My Fear Is Not, and Never Will Be, Your Fear: On Emotions and Feelings in Animals
2022 Affective Science article Veterinary Animal Behavior and Welfare Studies Open access

Mariska Esther Kret, Jorg J. M. Massen, Frans Β. Μ. de Waal

39

citations
MALDI-TOF MS and genomic analysis can make the difference in the clarification of canine brucellosis outbreaks
2020 Scientific Reports article Veterinary Brucella: diagnosis, epidemiology, treatment Open access

David Attuy Vey da Silva, Holger Brendebach, Josephine Grützke, Ralf Dieckmann, Rodrigo Martins Soares, Júlia Teresa Ribeiro de Lima, +3 more

16

citations
Animal-free strategies in food safety & nutrition: What are we waiting for? Part II: Nutrition research
2022 Trends in Food Science & Technology article Veterinary Animal testing and alternatives Open access

Alie de Boer, Johanneke van der Harst, Markus Fehr, Lucie Geurts, Karen Knipping, Nynke I. Kramer, +6 more

13

citations
Evaluation of score parameters for severity assessment of surgery and liver cirrhosis in rats
2023 Animal Welfare article Veterinary Animal testing and alternatives Open access

Johanne C. Krueger, Moriz Habigt, Marius Julian Helmedag, Moritz Uhlig, Michaela Moss, André Bleich, +4 more

4

citations
Stakeholder input towards further refinement and consolidation of the alternative safety profiling algorithm (ASPA) for next generation risk assessment (NGRA)
2026 ALTEX article Veterinary Animal testing and alternatives Open access

Mirjam Luijten, Matthias Herzler, Femke Affourtit, Dave Allen, Muhammad Waqar Ashraf, Nicholas S. Ball, +47 more

1

citations
Corridor-based relative severity assessment of the canine anaesthetic course
2026 Frontiers in Veterinary Science article Veterinary Veterinary Pharmacology and Anesthesia Open access

Julia D. Kschonek, Sabine Kästner, Philipp L. S. Ohland, Sara Lutscher, Holger Andreas Volk, Steven R. Talbot

0

citations