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Transport‐related effects on intrinsic and synaptic properties of human cortical neurons: A comparative study2026 The Journal of Physiology article Neuroscience Neuroscience and Neuropharmacology Research Open access
Guanxiao Qi, Danqing Yang, Aniella Bak, Werner Hucko, Daniel Delev, Hussam Aldin Hamou, +2 more
3citations -
Exploring Kp,uu,BBB values smaller than unity in remoxipride: A physiologically-based CNS model approach highlighting brain metabolism in drugs with passive blood-brain barrier transport2024 European Journal of Pharmaceutical Sciences article Neuroscience Barrier Structure and Function Studies Open access
Mengxu Zhang, Ilona M. Vuist, Vivi Rottschäfer, Elizabeth C. M. de Lange
3citations -
The RhoGEF Trio regulates the formation of tensile linear endothelial junctions to improve barrier function2025 Molecular Biology of the Cell article Neuroscience Barrier Structure and Function Studies Open access
Jos van Rijssel, Thijs J. Sluiter, Jeffrey M. A. van der Krogt, Cindy I. Bart, Juan Zhang, Antoine A.F. de Vries, +7 more
0citations -
Hydrogen-Bonding and Hydrophobic Interaction Networks as Structural Determinants of Microbial Rhodopsin Function2024 The Journal of Physical Chemistry B article Neuroscience Photoreceptor and optogenetics research
Éva Bertalan, Masae Konno, Marı́a del Carmen Marı́n, Reza Bagherzadeh, Takashi Nagata, Leonid S. Brown, +2 more
8citations -
Normal hearing function genetics: have you heard all about it? An integrated approach of genome-wide association studies and transcriptome-wide association studies in three Italian cohorts
Aurora Santin, Giulia Pianigiani, Alessandro Gialluisi, Alessandro Pecori, Beatrice Spedicati, Mariarosaria Persichillo, +13 more
2citations -
Lumbar cerebrospinal fluid-to-brain extracellular fluid surrogacy is context-specific: insights from LeiCNS-PK3.0 simulations2021 Journal of Pharmacokinetics and Pharmacodynamics article Neuroscience Barrier Structure and Function Studies Open access
Mohammed A. A. Saleh, Chi Fong Loo, Jeroen Elassaiss‐Schaap, Elizabeth C. M. de Lange
43citations -
Modeling ischemic stroke in a triculture neurovascular unit on-a-chip2021 Fluids and Barriers of the CNS article Neuroscience Barrier Structure and Function Studies Open access
Nienke R. Wevers, Arya Lekshmi Nair, Tania M. Fowke, Maria Pontier, Dhanesh G. Kasi, Xandor M. Spijkers, +6 more
77citations -
Blood-brain barrier perturbations by uremic toxins: Key contributors in chronic kidney disease-induced neurological disorders?2023 European Journal of Pharmaceutical Sciences article Neuroscience Barrier Structure and Function Studies Open access
Quentin Faucher, Thomas K. van der Made, Elizabeth C. M. de Lange, Rosalinde Masereeuw
42citations -
Evaluation of Antiviral Drugs’ Central Nervous System Distribution Using In Vitro Blood–Brain and Blood-CSF Barrier Models: The Impact of Serum Protein Concentration2026 Cellular and Molecular Neurobiology article Neuroscience Barrier Structure and Function Studies Open access
Malik Johid Reza, Ukamaka O. Modebelu, Courtney Vail Fletcher, Nagadenahalli Byrareddy Siddappa, Robbyn Kimberly Anand, Tianyi Zhang, +6 more
0citations -
The Extension of the LeiCNS-PK3.0 Model in Combination with the “Handshake” Approach to Understand Brain Tumor Pathophysiology2022 Pharmaceutical Research article Neuroscience Barrier Structure and Function Studies Open access
Makoto Hirasawa, Mohammed A. A. Saleh, Elizabeth C. M. de Lange
7citations -
Using the LeiCNS-PK3.0 Physiologically-Based Pharmacokinetic Model to Predict Brain Extracellular Fluid Pharmacokinetics in Mice2023 Pharmaceutical Research article Neuroscience Barrier Structure and Function Studies Open access
Mohammed A. A. Saleh, Berfin Gülave, Olivia Campagne, Clinton F. Stewart, Jeroen Elassaiss‐Schaap, Elizabeth C. M. de Lange
5citations -
Induction of subtle blood-brain barrier dysfunction using preclinical diagnostic ultrasound combined with microbubbles2026 Fluids and Barriers of the CNS article Neuroscience Barrier Structure and Function Studies Open access
Shakira A. van der Panne, Isabella Z. Koster, Anita E. Grootemaat, Nicole N. van der Wel, Mario G. Ries, Helga E. de Vries, +3 more
0citations -
DNA Methyltransferase 1 (DNMT1) Acts on Neurodegeneration by Modulating Proteostasis-Relevant Intracellular Processes2020 International Journal of Molecular Sciences article Neuroscience Genetic Neurodegenerative Diseases Open access
Cathrin Bayer, Georg Pitschelatow, Nina Hannemann, Jenice Linde, Julia Reichard, Daniel Pensold, +1 more
21citations