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Do Brain Extracellular Fluid Concentrations Predict PET ‐Inferred Receptor Occupancy in Human CNS ? A Mechanistic Model‐Based Analysis of Dopamine D2 Receptor Ligands2026 Clinical Pharmacology & Therapeutics article Neuroscience Neurotransmitter Receptor Influence on Behavior Open access
Divakar Budda, J. G. Coen van Hasselt, Elizabeth C. M. de Lange
0citations -
D101-10 Breaking Barriers: Characterisation of the Intradermal Lipopolysaccharide Challenge as an In Vivo Model for Controlled Induction of Vascular Leakage in Healthy Volunteers2026 American Journal of Respiratory and Critical Care Medicine article Neuroscience Barrier Structure and Function Studies
Marella C. E. van Ruissen, Menno van Diemen, Liza Botros, I Tomljanovic, Hind Achbo, Dimitra Eleftheriou, +5 more
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Exploring Kp,uu,BBB values smaller than unity in remoxipride: A physiologically-based CNS model approach highlighting brain metabolism in drugs with passive blood-brain barrier transport2024 European Journal of Pharmaceutical Sciences article Neuroscience Barrier Structure and Function Studies Open access
Mengxu Zhang, Ilona M. Vuist, Vivi Rottschäfer, Elizabeth C. M. de Lange
3citations -
Simplified two-compartment neuron with calcium dynamics capturing brain-state specific apical-amplification, -isolation and -drive2025 Frontiers in Computational Neuroscience article Neuroscience Neural dynamics and brain function Open access
Elena Pastorelli, Alper Yegenoglu, Nicole Kolodziej, Willem A. M. Wybo, Francesco Simula, Sandra Diaz-Pier, +2 more
4citations