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The Hippocampal Response to Acute Corticosterone Elevation Is Altered in a Mouse Model for Angelman Syndrome2022 International Journal of Molecular Sciences article Neuroscience Stress Responses and Cortisol Open access
Eva M. G. Viho, A. Mattijs Punt, Ben Distel, René Houtman, Jan Kroon, Ype Elgersma, +1 more
8citations -
Translational evaluation of novel selective orexin-1 receptor antagonist JNJ-61393215 in an experimental model for panic in rodents and humans2020 Translational Psychiatry article Neuroscience Neurotransmitter Receptor Influence on Behavior Open access cited by 2 patents
Giacomo Salvadore, Pascal Bonaventure, Anantha Shekhar, Philip L. Johnson, Brian Lord, Brock T. Shireman, +14 more
51citations -
Using the LeiCNS-PK3.0 Physiologically-Based Pharmacokinetic Model to Predict Brain Extracellular Fluid Pharmacokinetics in Mice2023 Pharmaceutical Research article Neuroscience Barrier Structure and Function Studies Open access
Mohammed A. A. Saleh, Berfin Gülave, Olivia Campagne, Clinton F. Stewart, Jeroen Elassaiss‐Schaap, Elizabeth C. M. de Lange
5citations -
Simulating intracochlear electrocochleography with a combined model of acoustic hearing and electric current spread in the cochlea2020 The Journal of the Acoustical Society of America article Neuroscience Hearing, Cochlea, Tinnitus, Genetics
Margriet J. van Gendt, Kanthaiah Koka, Randy K. Kalkman, Hendrik Christiaan Stronks, Jeroen Johannes Briaire, Leonid M. Litvak, +1 more
12citations -
Application of the LeiCNS-PK model to quantitatively evaluate the roles of BBB active influx and brain metabolism of fluvoxamine and its serotonin transporter (SERT) occupancy in rat and human0citations
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A directional 3D neurite outgrowth model for studying motor axon biology and disease2021 Scientific Reports article Neuroscience Axon Guidance and Neuronal Signaling Open access cited by 2 patents
Xandor M. Spijkers, Svetlana Pasteuning-Vuhman, Jennifa C. Dorleijn, Paul Vulto, Nienke R. Wevers, R. Jeroen Pasterkamp
58citations -
Exploring Kp,uu,BBB values smaller than unity in remoxipride: A physiologically-based CNS model approach highlighting brain metabolism in drugs with passive blood-brain barrier transport2024 European Journal of Pharmaceutical Sciences article Neuroscience Barrier Structure and Function Studies Open access
Mengxu Zhang, Ilona M. Vuist, Vivi Rottschäfer, Elizabeth C. M. de Lange
3citations -
Gene coexpression patterns predict opiate-induced brain-state transitions2020 Proceedings of the National Academy of Sciences article Neuroscience Neurotransmitter Receptor Influence on Behavior Open access
Julia K. Brynildsen, Kyla D. Mace, Eli J. Cornblath, Carmen Weidler, Fabio Pasqualetti, Danielle S. Bassett, +1 more
41citations