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Lumbar cerebrospinal fluid-to-brain extracellular fluid surrogacy is context-specific: insights from LeiCNS-PK3.0 simulations2021 Journal of Pharmacokinetics and Pharmacodynamics article Neuroscience Barrier Structure and Function Studies Open access
Mohammed A. A. Saleh, Chi Fong Loo, Jeroen Elassaiss‐Schaap, Elizabeth C. M. de Lange
43citations -
Do Brain Extracellular Fluid Concentrations Predict PET ‐Inferred Receptor Occupancy in Human CNS ? A Mechanistic Model‐Based Analysis of Dopamine D2 Receptor Ligands2026 Clinical Pharmacology & Therapeutics article Neuroscience Neurotransmitter Receptor Influence on Behavior Open access
Divakar Budda, J. G. Coen van Hasselt, Elizabeth C. M. de Lange
0citations -
Dynamic compliance of the CSF system in iNPH (Part I) - in vitro investigation of the impact of spinal canal stenoses2026 Fluids and Barriers of the CNS article Neuroscience Cerebrospinal fluid and hydrocephalus Open access
Anne Benninghaus, Kevin Ebers, Hans Clusmann, Uwe Kehler, Luca Papavero, Klaus Radermacher
1citations -
Generation of a Model to Predict Differentiation and Migration of Lymphocyte Subsets under Homeostatic and CNS Autoinflammatory Conditions2020 International Journal of Molecular Sciences article Neuroscience Neuroinflammation and Neurodegeneration Mechanisms Open access
Catharina C. Groß, Marc Pawlitzki, Andreas Schulte‐Mecklenbeck, Leoni Rolfes, Tobias Ruck, Petra Hundehege, +3 more
5citations -
Beta-endorphin is the key endogenous opioid influencing morphine µ-opioid receptor occupancy in rat hypothalamus: a binding kinetic model analysis2025 European Journal of Pharmaceutical Sciences article Neuroscience Neuropeptides and Animal Physiology Open access
Divakar Budda, J. G. Coen van Hasselt, Elizabeth C. M. de Lange
5citations -
Does nonlinear blood-brain barrier transport matter for morphine dosing strategies?2023 bioRxiv (Cold Spring Harbor Laboratory) preprint Neuroscience Barrier Structure and Function Studies Open access
Berfin Gülave, Divakar Budda, Mohammed A. A. Saleh, J. G. Coen van Hasselt, Elizabeth C. M. de Lange
0citations
11 results