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Impact of enantiomer‐specific changes in pharmacokinetics between infants and adults on the target concentration of racemic ketorolac: A pooled analysis2020 British Journal of Clinical Pharmacology article Medicine Pharmaceutical studies and practices Open access
Michael E. Cloesmeijer, Michiel Joost van Esdonk, Anne M Lynn, Anne Smits, Dick Tibboel, Youssef Daali, +3 more
9citations -
Defining the unbound target exposure of teicoplanin, Part 2: Dose individualization through population pharmacokinetic modelling2026 Clinical Microbiology and Infection article Medicine Antibiotics Pharmacokinetics and Efficacy Open access
Jaap W.A. Mouton, Nynke G L Jager, E. Wallenburg, Jeroen A. Schouten, W. J.F.M. van der Velden, Lenneke F. J. van Groningen, +6 more
1citations -
Predictions of Bedaquiline and Pretomanid Target Attainment in Lung Lesions of Tuberculosis Patients using Translational Minimal Physiologically Based Pharmacokinetic Modeling2023 Clinical Pharmacokinetics article Medicine Antibiotics Pharmacokinetics and Efficacy Open access
Krina Mehta, Tingjie Guo, Piet H. van der Graaf, J. G. Coen van Hasselt
17citations -
Therapeutic drug monitoring of tacrolimus after kidney transplantation: trough concentration or area under curve‐based monitoring?2024 British Journal of Clinical Pharmacology article Medicine Renal Transplantation Outcomes and Treatments Open access
Teun van Gelder, Armin Gelinck, Soufian Meziyerh, Aiko P. J. de Vries, Dirk Jan A. R. Moes
38citations -
Target-site cefiderocol pharmacokinetics in soft tissues of healthy volunteers2024 Journal of Antimicrobial Chemotherapy article Medicine Antibiotics Pharmacokinetics and Efficacy Open access
Maria Sanz-Codina, Wisse van Os, Anh Duc Pham, Anselm Jorda, Michael Wölf-Duchek, Felix Bergmann, +7 more
8citations -
Impact of Continuous Infusion Meropenem PK/PD Target Attainment on C-Reactive Protein Dynamics in Critically Ill Patients With Documented Gram-Negative Hospital-Acquired or Ventilator-Associated Pneumonia2024 Clinical Pharmacokinetics article Medicine Antibiotics Pharmacokinetics and Efficacy Open access
Carla Troisi, Pier Giorgio Cojutti, Matteo Rinaldi, Tommaso Tonetti, J. G. Coen van Hasselt, Pierluigi Viale, +1 more
3citations -
Attainment of Target Antibiotic Levels by Oral Treatment of Left-Sided Infective Endocarditis: A POET Substudy2023 Clinical Infectious Diseases article Medicine Infective Endocarditis Diagnosis and Management Open access
Magnus Bock, Anna Marie Theut, J. G. Coen van Hasselt, Hengzhuang Wang, Kurt Fuursted, Niels Høiby, +23 more
46citations -
ISABELA Studies: Plasma Exposure and Target Engagement Do Not Explain the Lack of Efficacy of Ziritaxestat in Patients with Idiopathic Pulmonary Fibrosis2023 Clinical Pharmacology & Therapeutics article Medicine Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis Open access
Garrit Jentsch, Stéphane Delage, Matthew J. Randall, Bernt van den Blink, Yasmina Bauer, Florence Namour
10citations -
Population pharmacokinetics and pharmacodynamics of a novel vascular adhesion protein-1 inhibitor using a multiple-target mediated drug disposition model2020 Journal of Pharmacokinetics and Pharmacodynamics article Medicine Pharmaceutical studies and practices Open access
Nelleke Snelder, Sven Hoefman, Alberto García-Hernández, Hartmut Onkels, Tobias E. Larsson, Kirsten Riber Bergmann
1citations -
Defining the pharmacokinetic/pharmacodynamic index of piperacillin/tazobactam within a hollow-fibre infection model to determine target attainment in intensive care patients2024 JAC-Antimicrobial Resistance article Medicine Antibiotics Pharmacokinetics and Efficacy Open access
Suzanne A M Wenker, Najla Alabdulkarim, John Readman, Elise M. A. Slob, Giovanni Satta, Shanom Ali, +3 more
1citations -
Integrative model-based comparison of target site-specific antimicrobial effects: A case study with ceftaroline and lefamulin2024 International Journal of Antimicrobial Agents article Medicine Antibiotics Pharmacokinetics and Efficacy Open access
Wisse van Os, Anh Duc Pham, Sabine Eberl, Iris K. Minichmayr, J. G. Coen van Hasselt, Markus Alexander Zeitlinger
3citations -
The vanR Cd Mutation 343A>G, Resulting in a Thr115Ala Substitution, Is Associated with an Elevated Minimum Inhibitory Concentration (MIC) of Vancomycin in Clostridioides difficile Clinical Isolates from Florida2023 Microbiology Spectrum article Medicine Clostridium difficile and Clostridium perfringens research Open access
Ishani Wickramage, Zhong Peng, Soumyadeep Chakraborty, Céline Harmanus, Ed J. Kuijper, Sally F. Alrabaa, +2 more
9citations -
Physiologically Based Modelling Framework for Prediction of Pulmonary Pharmacokinetics of Antimicrobial Target Site Concentrations2022 Clinical Pharmacokinetics article Medicine Antibiotics Pharmacokinetics and Efficacy Open access
Linda B. S. Aulin, Sebastian Tommi Tandar, Torben van Zijp, Etienne van Ballegooie, Piet H. van der Graaf, Mohammed A. A. Saleh, +2 more
12citations -
Effects of antibiotic resistance, drug target attainment, bacterial pathogenicity and virulence, and antibiotic access and affordability on outcomes in neonatal sepsis: an international microbiology and drug evaluation prospective substudy (BARNARDS)
Kathryn Thomson, Calie Dyer, Feiyan Liu, Kirsty M. Sands, Edward A. R. Portal, Maria J. Carvalho, +79 more
138citations -
Why we should sample sparsely and aim for a higher target: Lessons from model‐based therapeutic drug monitoring of vancomycin in intensive care patients2020 British Journal of Clinical Pharmacology article Medicine Antibiotics Pharmacokinetics and Efficacy Open access
Tingjie Guo, Reinier M. van Hest, Lucas M. Fleuren, Luca F. Roggeveen, Rob J. Bosman, Peter H. J. van der Voort, +4 more
7citations -
Defining the unbound target exposure of teicoplanin, Part 1: Insights from the hollow-fibre system2026 Clinical Microbiology and Infection article Medicine Antibiotics Pharmacokinetics and Efficacy Open access
Jaap W.A. Mouton, J. Raaijmakers, S.T. Tandar, Nynke G L Jager, Rob ter Heine, Roger J. M. Brüggemann, +2 more
1citations