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Papers matching “pleiotropy” 18

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Cross-trait analyses with migraine reveal widespread pleiotropy and suggest a vascular component to migraine headache
2020 International Journal of Epidemiology article Medicine Migraine and Headache Studies Open access

Katherine M. Siewert, Derek M. Klarin, Scott M. Damrauer, Kyong‐Mi Chang, Philip S. Tsao, Themistocles L. Assimes, +90 more

84

citations
Multi-ancestry genome-wide association study improves resolution of genes, pathways and pleiotropy for lung function and chronic obstructive pulmonary disease
2022 medRxiv preprint Medicine Chronic Obstructive Pulmonary Disease (COPD) Research Open access

Nick R. G. Shrine, Abril G. Izquierdo, Jing Chen, Richard J. Packer, Robert J. Hall, Anna L. Guyatt, +90 more

7

citations
Genetically Determined Serum Calcium Levels and Markers of Ventricular Repolarization: A Mendelian Randomization Study in the UK Biobank
2021 Circulation Genomic and Precision Medicine article Medicine Cardiac electrophysiology and arrhythmias Open access

William John Young, Helen R. Warren, Dennis Owen Mook-Kanamori, Julia Ramírez, Stefan van Duijvenboden, Michele Orini, +6 more

21

citations
The role of disease-associated short tandem repeats in amyotrophic lateral sclerosis
2025 Brain Communications article Medicine Amyotrophic Lateral Sclerosis Research Open access cited by 1 patent

Joke J.F.A. van Vugt, Ramona A.J. Zwamborn, Erwin Bekema, Maarten Kooyman, Philippe Corcia, Philippe Couratier, +12 more

2

citations
Elucidating mechanisms of genetic cross-disease associations at the PROCR vascular disease locus
2022 Nature Communications article Medicine Blood Coagulation and Thrombosis Mechanisms Open access

David Stacey, Lingyan Chen, Paulina J. Stanczyk, Joanna M. M. Howson, Amy M. Mason, Stephen Burgess, +88 more

22

citations
Exploring the possible causal effects of cardiac blood biomarkers in dementia and cognitive performance: a Mendelian randomization study
2023 GeroScience article Medicine Dementia and Cognitive Impairment Research Open access

Michelle H. Zonneveld, Stella Trompet, J. Wouter Jukema, Raymond Noordam

11

citations
HMG-CoA reductase is a potential therapeutic target for migraine: a mendelian randomization study
2024 Scientific Reports article Medicine Migraine and Headache Studies Open access

Kang Qu, Mingxi Li, Peng Yu, Aarno V. Palotie, Alice Rogot Pressman, Andrea Carmine Belin, +62 more

5

citations
Common and Rare Variant Contributions to Bradyarrhythmias from Multi-Ancestry Meta-Analyses
2023 medRxiv preprint Medicine Cardiac electrophysiology and arrhythmias Open access

Lu-Chen C Weng, Joel T Rämö, Sean Joseph Jurgens, Shaan S. Khurshid, Mark D. Chaffin, Amelia Weber Hall, +55 more

0

citations
A cross-disease meta-GWAS identifies four new susceptibility loci shared between systemic sclerosis and Crohn’s disease
2020 Scientific Reports article Medicine Systemic Sclerosis and Related Diseases Open access

David González‐Serna, Eguzkine Ochoa, Elena López‐Isac, Antonio Julià, Frauke C. Degenhardt, Norberto Ortego‐Centeno, +77 more

25

citations
The impact of statin use on sepsis mortality
2024 Journal of clinical lipidology article Medicine Sepsis Diagnosis and Treatment Open access

Mohan Li, Raymond Noordam, Stella Trompet, Elizabeth Martha Winter, J. Wouter Jukema, M. Sesmu Arbous, +2 more

15

citations
The Impact of Statin Use on Sepsis Mortality
2023 preprint Medicine Sepsis Diagnosis and Treatment Open access

Mohan Li, Raymond Noordam, Stella Trompet, Elizabeth Martha Winter, J. Wouter Jukema, M. Sesmu Arbous, +2 more

2

citations
Genome-Wide Association Study (GWAS) of Serum Galactose-Deficient IgA1 Uncovers Shared Genetic Determinants with IgAN
2025 Journal of the American Society of Nephrology article Medicine Renal Diseases and Glomerulopathies

Lili Liu, Atlas Khan, Colin Reily, Stacy D. Hall, Todd J. Green, Bruce A. Julian, +12 more

1

citations
Meta-analysis of Genome wide Association Studies on Childhood ADHD Symptoms and Diagnosis Reveals 17 Novel Loci and 22 Potential Effector Genes
2024 medRxiv preprint Medicine Attention Deficit Hyperactivity Disorder Open access

Camiel M. van der Laan, Hill Fung Ip, Marijn Schipper, Jouke‐Jan Hottenga, Eva M. L. Krapohl, Isabell Brikell, +93 more

0

citations
A causal effects of gut microbiota in the development of migraine
2023 The Journal of Headache and Pain article Medicine Migraine and Headache Studies Open access

Qiang He, Wenjing Wang, Yang Xiong, Chuanyuan Tao, Lu Ma, Junpeng Ma, +65 more

50

citations
Systemic inflammatory markers in relation to cognitive function and measures of brain atrophy: a Mendelian randomization study
2022 GeroScience article Medicine Dementia and Cognitive Impairment Research Open access

Jiao Min Luo, Saskia le Cessie, Gerard J. Blauw, Claudio Franceschi, Raymond Noordam, Diana van Heemst

72

citations
BS8 Genetically-determined serum calcium levels influence markers of ventricular repolarisation: a mendelian randomisation study
2021 conference-paper Medicine Cardiac electrophysiology and arrhythmias Open access

William John Young, Helen R. Warren, Dennis Owen Mook-Kanamori, Julia Ramírez, Stefan van Duijvenboden, Michele Orini, +6 more

0

citations
MC1R and IRF4 Gene Variants Are Associated with p16INK4a-Positive Epidermal Cells
2025 JID Innovations article Medicine Nonmelanoma Skin Cancer Studies Open access

Raymond Noordam, P. Eline Slagboom, Diana van Heemst, David Andrew Gunn

0

citations
Mendelian Randomization Analysis of the IL-1 Cytokine Family Proteins Identifies IL1RL1 as a Potential Causal Contributor to Traumatic Brain Injury Prognosis
2026 Neurocritical Care article Medicine Traumatic Brain Injury and Neurovascular Disturbances Open access

Youngjune Bhak, Adel E Helmy, Edward Needham, David Krishna Menon, Varun Warrier, Romit J. Samanta, +91 more

0

citations

18 results