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Model‐based dose optimization framework for bedaquiline, pretomanid and linezolid for the treatment of drug‐resistant tuberculosis2023 British Journal of Clinical Pharmacology article Medicine Tuberculosis Research and Epidemiology Open access
Krina Mehta, Tingjie Guo, Piet H. van der Graaf, J. G. Coen van Hasselt
10citations -
LeiCNS-PK3.2: A physiologically based pharmacokinetic model framework for predicting intracellular concentrations of acyclovir and ganciclovir active metabolites2026 European Journal of Pharmaceutical Sciences article Medicine Drug Transport and Resistance Mechanisms Open access
Ming Sun, Martijn L. Manson, Tingjie Guo, Elizabeth C. M. de Lange
1citations -
Quantitative Systems Pharmacology Modeling Framework of Autophagy in Tuberculosis: Application to Adjunctive Metformin Host-Directed Therapy2022 Antimicrobial Agents and Chemotherapy article Medicine Tuberculosis Research and Epidemiology Open access
Krina Mehta, Tingjie Guo, Robert S. Wallis, Piet H. van der Graaf, J. G. Coen van Hasselt
5citations -
Quantitative Systems Pharmacology Modeling Framework of Autophagy in Tuberculosis: Application to Adjunctive Metformin Host-Directed Therapy2022 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Tuberculosis Research and Epidemiology Open access
Krina Mehta, Tingjie Guo, Robert S. Wallis, Piet H. van der Graaf, J. G. Coen van Hasselt
0citations -
Development of a national quality framework for palliative care in a mixed generalist and specialist care model: A whole-sector approach and a modified Delphi technique
Manon S. A. Boddaert, Joep Douma, Anne-Floor Q Dijxhoorn, René A. C. L. Héman, Carin C.D. van der Rijt, Saskia C. C. M. Teunissen, +2 more
26citations -
A bidirectionally coupled multiscale modeling framework for evaluating mechanobiological conditions in proximal femur fracture healing2026 German Medical Science (German Research Foundation) conference-paper Medicine Bone fractures and treatments Open access
Maximilian Praster, Jil Frank, Rald V. M. Groven, Sabine Roth, Frank Hildebrand, Ulf Krister Hofmann
0citations -
Diffusion–reaction compartmental models formulated in a continuum mechanics framework: application to COVID-19, mathematical analysis, and numerical study2020 Computational Mechanics article Medicine Mathematical and Theoretical Epidemiology and Ecology Models Open access
Alex Viguerie, Alessandro Veneziani, Guillermo Lorenzo, Davide Baroli, Nicole Aretz, Alessia Patton, +4 more
92citations -
Development of a Quality Management Model and Self-assessment Questionnaire for Hybrid Health Care: Concept Mapping Study2022 JMIR Formative Research article Medicine Telemedicine and Telehealth Implementation Open access
Rosian Tossaint-Schoenmakers, Marise Jeannine Kasteleyn, Anneloek Rauwerdink, Niels Henrik Chavannes, Sofie H Willems, Esther P. W. A. Talboom-Kamp
15citations -
Expanding the options for therapeutic exon skipping as a future treatment for USH2A -associated disease by 3D structural modeling of newly formed hybrid domains2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Retinal Development and Disorders Open access
Lucija Malinar, Sanne Broekman, Daniel T. Rademaker, Anh Q Le, Theo A. Peters, Erik de Vrieze, +3 more
1citations -
The PBPK LeiCNS-PK3.0 framework predicts Nirmatrelvir (but not Remdesivir or Molnupiravir) to achieve effective concentrations against SARS-CoV-2 in human brain cells2022 European Journal of Pharmaceutical Sciences article Medicine SARS-CoV-2 and COVID-19 Research Open access
Mohammed A. A. Saleh, Makoto Hirasawa, Ming Sun, Berfin Gülave, Jeroen Elassaiss‐Schaap, Elizabeth C. M. de Lange
10citations -
Finitewave: a lightweight and accessible framework for cardiac electrophysiology simulations2026 Zenodo (CERN European Organization for Nuclear Research) software Medicine Cardiac electrophysiology and arrhythmias Open access
Timur V. Nezlobinsky, Arstanbek Okenov, Nele Vandersickel, Alexander Panfilov
0citations -
Finitewave: a lightweight and accessible framework for cardiac electrophysiology simulations2026 Zenodo (CERN European Organization for Nuclear Research) software Medicine Cardiac electrophysiology and arrhythmias Open access
Timur V. Nezlobinsky, Arstanbek Okenov, Nele Vandersickel, Alexander Panfilov
0citations -
Finitewave: a lightweight and accessible framework for cardiac electrophysiology simulations2026 Zenodo (CERN European Organization for Nuclear Research) software Medicine Cardiac electrophysiology and arrhythmias Open access
Timur V. Nezlobinsky, Arstanbek Okenov, Nele Vandersickel, Alexander V. Panfilov
0citations -
An interpretable machine learning framework with data-informed imaging biomarkers for diagnosis and prediction of Alzheimer’s disease2026 Computerized Medical Imaging and Graphics article Medicine Dementia and Cognitive Impairment Research Open access
Wenjie Kang, Bo Li, Lize Corrine Jiskoot, Peter Paul De Deyn, Geert Jan Biessels, Huiberdina L. Koek, +6 more
8citations