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Papers matching “model aggregation” 115

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Monitoring alpha-synuclein aggregation and transmission in an in vivo model of Parkinson’s disease
2020 RWTH Publications (RWTH Aachen) dissertation Medicine Parkinson's Disease Mechanisms and Treatments Open access

Vibha Prasad

0

citations
The porcine abattoir blood model—Evaluation of platelet function for in‐vitro hemocompatibility investigations
2021 Artificial Organs article Medicine Platelet Disorders and Treatments Open access

Johanna C. Clauser, Judith Maas, Ilona Mager, Frank Ruben Halfwerk, Jutta Arens

5

citations
Different force fields give rise to different amyloid aggregation pathways in molecular dynamics simulations
2020 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Alzheimer's disease research and treatments

Suman Samantray, Feng Yin, Batuhan Kav, Birgit Strodel

4

citations
Different Force Fields Give Rise to Different Amyloid Aggregation Pathways in Molecular Dynamics Simulations
2020 Journal of Chemical Information and Modeling article Medicine Alzheimer's disease research and treatments

Suman Samantray, Feng Yin, Batuhan Kav, Birgit Strodel

124

citations
Apolipoprotein E aggregation in microglia initiates Alzheimer’s disease pathology by seeding β-amyloidosis
2024 Immunity article Medicine Alzheimer's disease research and treatments Open access

Seiji Kaji, Stefan A. Berghoff, Lena Spieth, Lennart Schlaphoff, Andrew Octavian Sasmita, Luca Büschgens, +22 more

105

citations
Association Between Vascular NOTCH3 Aggregation and Disease Severity in a CADASIL Cohort – Implications for NOTCH3 Variant‐Specific Disease Prediction
2025 Annals of Neurology article Medicine Cerebrovascular and genetic disorders Open access

Minne N. Cerfontaine, Gido Gravesteijn, Remco J. Hack, Kyra L. Dijkstra, Mar Rodríguez‐Girondo, Benno G. Gesierich, +5 more

4

citations
A 3D human co-culture to model neuron-astrocyte interactions in tauopathies
2023 Biological Procedures Online article Medicine Alzheimer's disease research and treatments Open access

Kevin Llewelyn Batenburg, Claudia Sestito, Paulien Cornelissen‐Steijger, Jan R.T. van Weering, Leo Price, Vivi Majella Heine, +1 more

18

citations
Targeting the N-terminus of α-synuclein Monomer Reduces Fibril-induced Aggregation in the Brain
2020 preprint Medicine Parkinson's Disease Mechanisms and Treatments Open access

Éva M. Szegő, Fabian Boß, Daniel Komnig, Charlott Gärtner, Lennart Höfs, Hamed Shaykhalishahi, +5 more

1

citations
The use of cryopreserved platelets in a trauma‐induced hemorrhage model
2020 Transfusion article Medicine Trauma, Hemostasis, Coagulopathy, Resuscitation Open access

Derek J. B. Kleinveld, Pieter H. Sloos, Femke Noorman, M.A.W. Maas, Jesper Kers, Tim W.H. Rijnhout, +4 more

18

citations
A β-Wrapin Targeting the N-Terminus of α-Synuclein Monomers Reduces Fibril-Induced Aggregation in Neurons
2021 Frontiers in Neuroscience article Medicine Parkinson's Disease Mechanisms and Treatments Open access

Éva M. Szegő, Fabian Boß, Daniel Komnig, Charlott Gärtner, Lennart Höfs, Hamed Shaykhalishahi, +5 more

14

citations
Nuclear Protein Aggregates Disrupt RNA Processing and Alter Biomechanics in a Muscle Cell Model of OPMD
2025 Aging and Disease article Medicine Amyotrophic Lateral Sclerosis Research Open access

Milad Shademan, Sarah E. Flannery, Erik Bos, Tom M. J. Evers, Vahid Sheikhhassani, Alireza Mashaghi, +5 more

3

citations
Active immunotherapy reduces NOTCH3 deposition in brain capillaries in a CADASIL mouse model
2022 EMBO Molecular Medicine article Medicine Cerebrovascular and genetic disorders Open access

Daniel V. Oliveira, Kirsten Coupland, Wenchao Shao, Shaobo Jin, Francesca Del Gaudio, Sailan Wang, +8 more

29

citations
TDP‐43 dysregulation and STMN‐2 mis‐splicing upon proteasomal inhibition in potential iPSC‐derived neuronal ALS model
2023 Alzheimer s & Dementia article Medicine Amyotrophic Lateral Sclerosis Research

Laila Ritsma, Malika Bsibsi, Abeera Popalzij, Sara Compte-Sancerni, Esther de Kraa, Dario Magnani, +4 more

1

citations
Close-to-Patient Models for Gastric Cancer: From Patient-Derived Xenograft Towards a Novel Gastric Cancer Mini-Tumor Model
2026 OncoTargets and Therapy article Medicine Gastric Cancer Management and Outcomes Open access

Sarah K. Hakuno, J. B. M. Zonneveld, Stefanus G. T. Janson, Anthea Van der Wielen, Eleonore B Kuhlemaijer, Maud Steenbakkers, +9 more

0

citations
A fresh look at mycobacterial pathogenicity with the zebrafish host model
2021 Molecular Microbiology article Medicine Tuberculosis Research and Epidemiology Open access

Mónica Varela, Annemarie H. Meijer

30

citations
Solid tumor-on-chip model for efficacy and safety assessment of CAR-T cell therapy
2023 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine CAR-T cell therapy research Open access

Tengku Ibrahim Maulana, Claudia Teufel, Madalena Cipriano, Lisa Lazarevski, Francijna E. van den Hil, Valeria V. Orlova, +4 more

2

citations
NOTCH3 active immunotherapy reduces NOTCH3 deposition in brain capillaries in a CADASIL mouse model
2022 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Cerebrovascular and genetic disorders Open access

Daniel V. Oliveira, Kirsten Coupland, Shaobo Jin, Francesca Del Gaudio, Sailan Wang, Rhys Fox, +6 more

0

citations
Pathomechanisms of ALS8: altered autophagy and defective RNA binding protein (RBP) homeostasis due to the VAPB P56S mutation
2021 Cell Death and Disease article Medicine Amyotrophic Lateral Sclerosis Research Open access

Priyanka Tripathi, Haihong Guo, Alice Dreser, Alfred Yamoah, Antonio S. Sechi, Christopher Marvin Jesse, +12 more

25

citations
A Systematic Review of Differential Equation Models of Neurodegenerative Disease Dynamics: Methods, Architectures, and Future Research Directions
2025 International Journal on Advanced Computer Theory and Engineering review Medicine Alzheimer's disease research and treatments Open access

A. G. Lewis, B. Horváth, R. Costa

0

citations
AAV-Delivered Anti-PC-OxPL Antibody Fragments: A Novel Therapeutic Approach to Target ALS
2025 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Amyotrophic Lateral Sclerosis Research

Andreia Gomes‐Duarte, Jamie K. Wong, Svetlana Pasteuning-Vuhman, Wouter Pos, Rob Haselberg, Marina Sogorb-González, +6 more

1

citations
Brain geometry matters in Alzheimer’s disease progression: a simulation study
2020 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Alzheimer's disease research and treatments Open access

Masoud Hoore, Jeffrey Kelling, Mahsa Sayadmanesh, Tanmay Mitra, Marta Schips, Michael Meyer‐Hermann

1

citations
Neutralization of pathogenic PC-OxPL by AAV-delivered scFv as a therapeutic strategy for amyotrophic lateral sclerosis
2026 Molecular Therapy Advances article Medicine Amyotrophic Lateral Sclerosis Research Open access

Andreia Gomes‐Duarte, Jamie K. Wong, Alessandro Moro, Svetlana Pasteuning-Vuhman, Wouter Pos, Rob Haselberg, +8 more

0

citations
Mutation in PDGFRbeta: a potential new pathogenic variant for mitral valve prolapse
2023 European Heart Journal article Medicine Cardiac Valve Diseases and Treatments

Aniek L. van Wijngaarden, Babak Mousavi Gourabi, Anke M. Smits, Daniela Q.C.M. Barge‐Schaapveld, Antoine A.F. de Vries, J. Wouter Jukema, +2 more

0

citations
Mutation in PDGFRbeta: a potential new pathogenic variant for acquired mitral valve prolapse
2024 Cardiovascular Research article Medicine Cardiac Valve Diseases and Treatments Open access

Huawei Wu, M El Ouraoui, A L Van Wijnwaarden, Babak Mousavi Gourabi, Anke M. Smits, Daniela Q.C.M. Barge‐Schaapveld, +4 more

0

citations
582P Preclinical development of AT1412, a patient derived CD9 antibody that does not induce thrombosis for treatment of precursor B ALL
2020 Annals of Oncology article Medicine Acute Lymphoblastic Leukemia research Open access

Julien Villaudy, Remko Schotte, Greta de Jong, Viviana Neviani, Wouter Pos, Sophie E. Levie, +14 more

3

citations