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Unraveling A4GALT Mechanism and Its Modulation With Adamantyl‐Galactosylceramide Analogues: Advancing Fabry Disease Therapeutic Strategies2026 Angewandte Chemie International Edition article Medicine Lysosomal Storage Disorders Research Open access
Nicky de Koster, Òscar Vidal-Gironès, Rowan de Graaf, Ken Kok, Lindsey T. Lelieveld, Jackelien Hoogervorst, +8 more
1citations -
Therapeutic challenges in two adolescent male patients with Fabry disease and high antibody titres2020 Molecular Genetics and Metabolism Reports article Medicine Lysosomal Storage Disorders Research Open access
Aizeddin A. Mhanni, Christiane Auray‐Blais, Michel Boutin, Alie J. Johnston, Kaye M. LeMoine, Johannes M. F. G. Aerts, +2 more
8citations -
Fabry Disease: Molecular Basis, Pathophysiology, Diagnostics and Potential Therapeutic Directions2021 Biomolecules article Medicine Lysosomal Storage Disorders Research Open access cited by 1 patent
Ken Kok, Kimberley C. Zwiers, Rolf G. Boot, Herman S. Overkleeft, Johannes M. F. G. Aerts, Marta Artola
131citations -
Natural disease course of chronic visceral acid sphingomyelinase deficiency in adults: A first step toward treatment criteria2024 Journal of Inherited Metabolic Disease article Medicine Lysosomal Storage Disorders Research Open access
Eline C. B. Eskes, Laura van Dussen, Marion M. M. G. Brands, Frédéric Maxime Vaz, Johannes M. F. G. Aerts, André B. P. Kuilenburg, +2 more
8citations -
Unravelling key enzymatic steps in C-ring cleavage during angucycline biosynthesis2023 Communications Chemistry article Medicine Microbial Natural Products and Biosynthesis Open access
Somayah S. Elsayed, Helga U. van der Heul, Xiansha Xiao, Aleksi Nuutila, Laura R. Baars, Changsheng Wu, +2 more
10citations -
Potent Inhibition of SARS-CoV-2 nsp14 N 7-Methyltransferase by Sulfonamide-Based Bisubstrate Analogues2022 Journal of Medicinal Chemistry article Medicine SARS-CoV-2 and COVID-19 Research Open access cited by 1 patent
Rostom Ahmed‐Belkacem, Marcel Hausdorff, Adrien Delpal, Priscila Sutto‐Ortiz, Agathe M. G. Colmant, Franck Touret, +7 more
60citations -
Immunogenicity and safety of different dose levels of Ad26.RSV.preF/RSV preF protein vaccine in adults aged 60 years and older: A randomized, double-blind, placebo-controlled, phase 2a study
Roy van Heesbeen, Arangassery Rosemary Bastian, Edmund V Ekoka Omoruyi, Christy A. Comeaux, Benoît Callendret, Esther Heijnen
4citations -
Glycoform-resolved pharmacokinetic studies in a rat model employing glycoengineered variants of a therapeutic monoclonal antibody2020 mAbs article Medicine Monoclonal and Polyclonal Antibodies Research Open access cited by 2 patents
David Falck, Marco Thomann, Martin Lechmann, Carolien A. M. Koeleman, Sebastian Malik, Cordula Jany, +2 more
42citations -
Pontocerebellar hypoplasia due to bi-allelic variants in MINPP12020 European Journal of Human Genetics article Medicine Fetal and Pediatric Neurological Disorders Open access
Bart Appelhof, Matias Wagner, Julia Hoefele, Timo Roser, Margarete Koch‐Hogrebe, Stefan D. Roosendaal, +10 more
30citations -
The α1- and β1-Subunits of Nitric Oxide-Sensitive Guanylyl Cyclase in Pericytes of Healthy Human Dental Pulp2024 International Journal of Molecular Sciences article Medicine Nitric Oxide and Endothelin Effects Open access
Yüksel Korkmaz, Galyna Pryymachuk, Mechthild M. Schroeter, Behrus Puladi, Nadin Piekarek, Sarah Appel, +4 more
1citations -
Molecular Modeling of Protein–Peptide Complexes Mimicking Factor Xa–Prothrombin Using AlphaFold-Multimer and Molecular Dynamics Simulations for Functional Prediction2026 Journal of Chemical Information and Modeling article Medicine Blood Coagulation and Thrombosis Mechanisms
Dejvid Veizaj, David Alonzo Poole III, Ka Lei Cheung, Jos V. Flier, Pieter H. Reitsma, Daniël Verhoef, +2 more
1citations -
Crystallographic characterisation and development of bi-substrate inhibitors of coronavirus nsp14 methyltransferase2025 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine SARS-CoV-2 and COVID-19 Research Open access
Irene Georgiou, Colin Robinson, Sean N. O’Byrne, Alex Matsuda, Przemysław Grygier, Shamshad Ahmad, +17 more
1citations
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