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Step-in Dosing in the Bosutinib Dose Optimization Study (BODO) Failed to Reduce Gastrointestinal (GI) Toxicity in Patients Failing Second Generation TKI (2G-TKI) in Chronic Phase Chronic Myeloid Leukemia (CML) but Suggests Promising Molecular Response
Susanne Isfort, Dominik Georg Friedrich Wolf, Lino Lars Teichmann, Martina Margrit Crysandt, Andreas Burchert, Andreas Hochhaus, +11 more
5citations -
Triheptanoin Did Not Show Benefit versus Placebo for the Treatment of Paroxysmal Movement Disorders in Glut1 Deficiency Syndrome: Results of a Randomized Phase 3 Study
Valentina DE GIORGIS, Kailash P. Bhatia, Odile Boespflug‐Tanguy, Domitille Gras, Adela Della Marina, Archana Desurkar, +10 more
15citations -
Sleep disturbances in the prodromal phase of mood episodes in patients with bipolar disorder: a replicated single-case design2025 Journal for Person-Oriented Research article Medicine Bipolar Disorder and Treatment Open access
Stefan E. Knapen, Evelien Snippe, Arnout Christiaan Smit, Robert A. Schoevers, Rixt F. Riemersma‐van der Lek
1citations -
Temporal patterns of immune-mediated adverse events (imAEs) with tremelimumab (T) plus durvalumab (D) in the phase 3 HIMALAYA study in unresectable hepatocellular carcinoma (uHCC).2023 Journal of Clinical Oncology conference-abstract Medicine Cancer Immunotherapy and Biomarkers Open access
George K.K. Lau, Bruno Sangro, Oxana Crysler, Wattana Sukeepaisarnjaroen, Oleg Nikolaevich Lipatov, Manabu Morimoto, +12 more
8citations -
Addition of Isatuximab to Lenalidomide, Bortezomib and Dexamethasone As Induction Therapy for Newly-Diagnosed, Transplant-Eligible Multiple Myeloma Patients: The Phase III GMMG-HD7 Trial
Hartmut Goldschmidt, Eva Nievergall, Roland R. Fenk, Uta Bertsch, Diana Tichy, Britta Besemer, +25 more
33citations -
Chemoradiotherapy versus short-course radiotherapy for response-adapted organ preservation in early-stage and intermediate-stage rectal cancer (STAR-TREC): 12-month results of an international, multicentre, open-label, parallel-group, randomised, phase 2/3 trial
Simon Parkinson Bach, David Sebag‐Montefiore, Victoria Homer, Alexandra Gilbert, Ane Lindegaard Appelt, Ian Geh, +94 more
0citations -
Targeting for Success: Demonstrating Proof-of-Concept with Mechanistic Early Phase Clinical Pharmacology Studies for Disease-Modification in Neurodegenerative Disorders2021 International Journal of Molecular Sciences article Medicine Alzheimer's disease research and treatments Open access
Maurits F. J. M. Vissers, Jules A. A. C. Heuberger, Geert Jan Groeneveld
22citations -
Levothyroxine in euthyroid thyroid peroxidase antibody positive women with recurrent pregnancy loss (T4LIFE trial): a multicentre, randomised, double-blind, placebo-controlled, phase 3 trial2022 The Lancet Diabetes & Endocrinology article Medicine Thyroid Disorders and Treatments Open access
Marie‐Louise van der Hoorn, Ole Bjarne Christiansen, Madelon van Wely
95citations -
MON-314 Analysis of Adverse Events in Adult Patients with Acromegaly Receiving Oral Octreotide Capsules: Results from the Phase 3, Randomized, Double-Blind, Placebo-Controlled CHIASMA OPTIMAL Study2020 Journal of the Endocrine Society article Medicine Pituitary Gland Disorders and Treatments Open access
Artak Labadzhyan, Susan Leanne Samson, Lisa B. Nachtigall, Maria Fleseriu, William Henry Ludlam, H Patou, +7 more
0citations -
PO.6.137 Design of a phase 2, multicenter, randomized, placebo-controlled, parallel-group, double-blind study to assess the efficacy and safety of nipocalimab in adults with active systemic lupus erythematosus
Fang Liu-walsh, Bart van Hartingsveldt, Qing Zuraw, RW Hoffman, Terence P. Rooney, Sheng Gao, +6 more
0citations -
First safety analysis of an open-label, single arm phase II trial investigating the efficacy, safety and quality of life of neoadjuvant chemotherapy with liposomal irinotecan combined with oxaliplatin and 5-fluoruracil/folinic acid followed by curative surgical resection in patients with hepatic oligometastatic adenocarcinoma of the pancreas (HOLIPANC).2025 Journal of Clinical Oncology conference-abstract Medicine Pancreatic and Hepatic Oncology Research Open access
Dirk Waldschmidt, Nam Gyu Im, Alexander Ioannis Damanakis, Thomas Schmidt, Albrecht Meyer zu Schwabedissen, Alexander Quaas, +13 more
0citations -
Autologous haematopoietic stem-cell transplantation versus bortezomib–melphalan–prednisone, with or without bortezomib–lenalidomide–dexamethasone consolidation therapy, and lenalidomide maintenance for newly diagnosed multiple myeloma (EMN02/HO95): a multicentre, randomised, open-label, phase 3 study2020 The Lancet Haematology article Medicine Multiple Myeloma Research and Treatments Open access cited by 2 patents
Michèle Cavo, Francesca Gay, Meral Beksaç, Lucia Pantani, Maria Teresa Petrucci, Meletios Athanasios Dimopoulos, +54 more
384citations -
Conversion from Calcineurin Inhibitor– to Belatacept-Based Maintenance Immunosuppression in Renal Transplant Recipients: A Randomized Phase 3b Trial2021 Journal of the American Society of Nephrology article Medicine Renal Transplantation Outcomes and Treatments Open access
Klemens Budde, Rohini Prashar, Hermann G. Haller, Maria C. Rial, Nassim Kamar, Avinash Kumar Ágarwal, +9 more
105citations -
Characteristics of Patients Who Achieve Serum Phosphorus Control on Sucroferric Oxyhydroxide or Sevelamer Carbonate: A post hoc Analysis of a Phase 3 Study2020 The Nephron journals/Nephron journals article Medicine Parathyroid Disorders and Treatments Open access
Adrian Constantin Covic, Stuart Michael Sprague, Anjay Rastogi, Markus Ketteler, Sebastian Walpen, Amandine Perrin, +1 more
4citations -
Randomized Phase II Study of All-Trans Retinoic Acid and Valproic Acid Added to Decitabine in Newly Diagnosed Elderly AML Patients (DECIDER trial): Predictive Impact of TP53 Status
Heiko Becker, Claudia Schmoor, Olga Grishina, Dietmar Pfeifer, Dennis Zimmer, Martina Margrit Crysandt, +27 more
3citations -
MON-LB53 Prior Injectable Somatostatin Receptor Ligand Dose Does Not Predict Oral Octreotide Response In The Treatment Of Acromegaly: Results From The Phase 3 OPTIMAL Study2020 Journal of the Endocrine Society article Medicine Pituitary Gland Disorders and Treatments Open access
Lisa B. Nachtigall, Susan Leanne Samson, Maria Fleseriu, Marek Bolanowski, William Henry Ludlam, Gary Patou, +7 more
0citations -
MON-297 Withdrawal from Long-Acting Somatostatin Receptor Ligand Injections in Adult Patients with Acromegaly: Results from the Phase 3, Randomized, Double-Blind, Placebo-Controlled CHIASMA OPTIMAL Study2020 Journal of the Endocrine Society article Medicine Pituitary Gland Disorders and Treatments Open access
Lisa B. Nachtigall, Susan Leanne Samson, Maria Fleseriu, Marek Bolanowski, William Henry Ludlam, Gary Patou, +7 more
0citations