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Successful pharmacological intervention at different levels of the complement system in an in vitro complement fixation model for bullous pemphigoid
Jenny Giang, Martijn B. A. van Doorn, Gilles F.H. Diercks, Santiago Rodrı́guez de Córdoba, Thierry P. P. van den Bosch, Marco W.J. Schreurs, +2 more
3citations -
Treatment of COVID-19 With Conestat Alfa, a Regulator of the Complement, Contact Activation and Kallikrein-Kinin System2020 Frontiers in Immunology article Medicine COVID-19 Clinical Research Studies Open access cited by 3 patents
Pascal Urwyler, Stephan Moser, Panteleimon Charitos, Ingmar Heijnen, Melanie Rudin, Gregor Sommer, +5 more
85citations -
Tackling Neuroinflammation After Traumatic Brain Injury: Complement Inhibition as a Therapy for Secondary Injury2022 Neurotherapeutics article Medicine Traumatic Brain Injury and Neurovascular Disturbances Open access
Inge A. M. van Erp, Iliana Michailidou, Thomas Arjan van Essen, Mathieu van der Jagt, Wouter A. Moojen, Wilco C. Peul, +2 more
67citations -
Therapeutic Intervention with Anti-Complement Component 5 Antibody Does Not Reduce NASH but Does Attenuate Atherosclerosis and MIF Concentrations in Ldlr-/-.Leiden Mice2022 International Journal of Molecular Sciences article Medicine Liver Disease Diagnosis and Treatment Open access
Florine Seidel, Robert Kleemann, Wim van Duyvenvoorde, Nikki van Trigt, Nanda Keijzer, Sandra van der Kooij, +10 more
15citations -
A system pharmacology Boolean network model for the TLR4-mediated inflammatory response in early sepsis2022 Journal of Pharmacokinetics and Pharmacodynamics article Medicine Sepsis Diagnosis and Treatment Open access
Feiyan Liu, Linda B. S. Aulin, Sebastiaan S. A. Kossen, Julius Cathalina, Marlotte Bremmer, Amanda C. Foks, +3 more
11citations -
Spatial profiling of the spleen in mouse and human myelofibrosis reveals complement-driven immune-stromal interactions as a therapeutic target2026 Cell stem cell article Medicine Myeloproliferative Neoplasms: Diagnosis and Treatment Open access
Bérénice Dugué, Pia Wanner, Mayra L. Ruiz Tejada Segura, Mohamed Saad, Lucas Greven, Katrin Götz, +33 more
2citations -
Circulating levels of endogenous complement inhibitors correlate inversely with complement consumption in systemic lupus erythematosus2024 European Journal of Immunology article Medicine Systemic Lupus Erythematosus Research Open access
Stef van der Meulen, Rory Caitlin Monahan, Kyra A. Gelderman, Cees van Kooten, Y K Onno Teng, Tom W. J. Huizinga, +2 more
3citations -
Balloon cells promote immune system activation in focal cortical dysplasia type 2b2021 Neuropathology and Applied Neurobiology article Medicine Epilepsy research and treatment Open access
Till S. Zimmer, Diede W. M. Broekaart, Mark J. Luinenburg, Caroline Mijnsbergen, Jasper J. Anink, Nam Suk Sim, +11 more
39citations -
Strengthening the WHO Emergency Care Systems Framework: insights from an integrated, patient-centered approach in the Copenhagen Emergency Medical Services system—a qualitative system analysis
Simone Böbel, Jeske Verhoeven, Mirjam Lisa Scholz, Bart Penders, Lorraine Frisina Doetter, Helle Collatz Christensen, +1 more
22citations -
The role of complement activation in autoimmune liver disease2020 Autoimmunity Reviews article Medicine Liver Diseases and Immunity Open access cited by 1 patent
Maaike Biewenga, Arantza Fariña Sarasqueta, Maarten E. Tushuizen, Eveline S. M. de Jonge‐Muller, Bart van Hoek, Leendert Adrianus Trouw
35citations -
Complement Activation Levels Are Related to Disease Stage in AMD2020 Investigative Ophthalmology & Visual Science article Medicine Retinal Diseases and Treatments Open access cited by 1 patent
Thomas J. Heesterbeek, Yara T. E. Lechanteur, Laura Lorés‐Motta, Tina Schick, Mohamed R. Daha, Lebriz Altay, +6 more
79citations -
Human anti-C1q autoantibodies bind specifically to solid-phase C1q and enhance phagocytosis but not complement activation2023 Proceedings of the National Academy of Sciences article Medicine Systemic Lupus Erythematosus Research Open access cited by 3 patents
Douwe J. Dijkstra, Fleur S. van de Bovenkamp, Leoni Abendstein, Rob Zuijderduijn, Jos Pool, Cynthia S. M. Kramer, +10 more
18citations