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In situ kinetic measurements of α-synuclein aggregation reveal large population of short-lived oligomers2021 PLoS ONE article Medicine Parkinson's Disease Mechanisms and Treatments Open access cited by 2 patents
Enrico Zurlo, Pravin Kumar, Georg Meisl, Alexander J. Dear, Dipro Mondal, Mireille M. A. E. Claessens, +2 more
22citations -
Acetyl-CoA Carboxylase Inhibitor CP640.186 Increases Tubulin Acetylation and Impairs Thrombin-Induced Platelet Aggregation2021 International Journal of Molecular Sciences article Medicine Platelet Disorders and Treatments Open access
Marie Octave, Laurence Pirotton, Audrey Ginion, Valentine Robaux, Sophie Lepropre, Jérôme Ambroise, +7 more
10citations -
The efficacy of aspirin to inhibit platelet aggregation in patients hospitalised with a severe infection: a multicentre, open-label, randomised controlled trial2023 Clinical and Experimental Medicine article Medicine Antiplatelet Therapy and Cardiovascular Diseases Open access
Lieve Mees van Zijverden, Moya Henriëtte Schutte, Milou Cecilia Madsen, Tobias Nicolaas Bonten, Yvo Michiel Smulders, Chantal Maria Wiepjes, +2 more
7citations -
NO TCH3 variant position is associated with NOTCH3 aggregation load in CADASIL vasculature2021 Neuropathology and Applied Neurobiology article Medicine Cerebrovascular and genetic disorders Open access
Gido Gravesteijn, Remco J. Hack, Aat A. Mulder, Minne N. Cerfontaine, Remco van Doorn, Ingrid M. Hegeman, +3 more
43citations -
Discovery of novel 6-hydroxybenzothiazole urea derivatives as dual Dyrk1A/α-synuclein aggregation inhibitors with neuroprotective effects2021 European Journal of Medicinal Chemistry article Medicine Parkinson's Disease Mechanisms and Treatments Open access
Yasmeen T. AlNajjar, Moustafa Tarek Gabr, Ahmed K. ElHady, Mohamed Salah, Gerrit Wilms, Alireza Abadi, +3 more
29citations -
A β-Wrapin Targeting the N-Terminus of α-Synuclein Monomers Reduces Fibril-Induced Aggregation in Neurons2021 Frontiers in Neuroscience article Medicine Parkinson's Disease Mechanisms and Treatments Open access
Éva M. Szegő, Fabian Boß, Daniel Komnig, Charlott Gärtner, Lennart Höfs, Hamed Shaykhalishahi, +5 more
14citations -
Acetyl-CoA carboxylase inhibition alters tubulin acetylation and aggregation in thrombin-stimulated platelets2021 Archives of Cardiovascular Diseases Supplements article Medicine Platelet Disorders and Treatments Open access
Marie Octave, Laurence Pirotton, Audrey Ginion, Valentine Robaux, Sophie Lepropre, Shakeel Kautbally, +8 more
0citations -
NOTCH3 VARIANT POSITION IS ASSOCIATED WITH VASCULAR NOTCH3 AGGREGATION LOAD IN CADASIL PATIENTS2024 Cerebral Circulation - Cognition and Behavior article Medicine Cerebrovascular and genetic disorders Open access
Gido Gravesteijn, Remco J. Hack, Aat A. Mulder, Minne N. Cerfontaine, Remco van Doorn, Ingrid M. Hegeman, +3 more
0citations -
α-Synuclein phosphorylation at serine 129 occurs after initial protein deposition and inhibits seeded fibril formation and toxicity2022 Proceedings of the National Academy of Sciences article Medicine Parkinson's Disease Mechanisms and Treatments Open access
Simona S. Ghanem, Nour K. Majbour, Nishant N. Vaikath, Mustafa Taleb Ardah, Daniel Erskine, Nanna Møller Jensen, +15 more
218citations -
Native, Intact Glucagon-Like Peptide 1 Is a Natural Suppressor of Thrombus Growth Under Physiological Flow Conditions2020 Arteriosclerosis Thrombosis and Vascular Biology article Medicine Platelet Disorders and Treatments Open access
Marieke Sternkopf, Magdolna Nagy, Constance C. F. M. J. Baaten, Marijke J. E. Kuijpers, Bibian M. E. Tullemans, Wendy Theelen, +13 more
35citations -
Discovery of Hydroxybenzothiazole Urea Compounds as Multitargeted Agents Suppressing Major Cytotoxic Mechanisms in Neurodegenerative Diseases2021 ACS Chemical Neuroscience article Medicine Alzheimer's disease research and treatments cited by 1 patent
Youssef Aboushady, Moustafa Tarek Gabr, Ahmed K. ElHady, Mohamed Salah, Alireza Abadi, Gerrit Wilms, +3 more
9citations -
Biophysical Characterization and Stability of Modified IgG1 Antibodies with Different Hexamerization Propensities2022 Journal of Pharmaceutical Sciences article Medicine Monoclonal and Polyclonal Antibodies Research Open access
Muriel D. van Kampen, Leonie H.A.M. de Wilt, Mariëlle L. van Egmond, Petra Reinders-Blankert, Ewald T.J. van den Bremer, Guanbo Wang, +5 more
13citations