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Human anti-C1q autoantibodies bind specifically to solid-phase C1q and enhance phagocytosis but not complement activation2023 Proceedings of the National Academy of Sciences article Medicine Systemic Lupus Erythematosus Research Open access cited by 3 patents
Douwe J. Dijkstra, Fleur S. van de Bovenkamp, Leoni Abendstein, Rob Zuijderduijn, Jos Pool, Cynthia S. M. Kramer, +10 more
18citations -
Anti‐C1q autoantibodies may not serve as an adequate biomarker for lung manifestations in systemic sclerosis: a single‐centre, cross‐sectional study2021 British Journal of Dermatology article Medicine Systemic Sclerosis and Related Diseases Open access
Douwe J. Dijkstra, Sophie I E Liem, Nina Marijn van Leeuwen, Cynthia M. Fehres, Jeska Kirsten De Vries-Bouwstra, Leendert Adrianus Trouw
1citations -
C1q-targeting bispecific antibodies bypass Fc to trigger complement activation and receptor clustering agonism2026 Molecular Immunology article Medicine Monoclonal and Polyclonal Antibodies Research Open access
Douwe J. Dijkstra, Marfa Blanter, Els van der Meijden, Rick J. Groenland, Clifford Rodriguez, Boris Bleijlevens, +2 more
0citations -
Inverse correlation between serum complement component C1q levels and whole blood type‐1 interferon signature in active tuberculosis and QuantiFERON‐positive uveitis: implications for diagnosis2020 Clinical & Translational Immunology article Medicine Tuberculosis Research and Epidemiology Open access
Benjamin Schrijver, Douwe J. Dijkstra, Nicole V. Borggreven, Rina La Distia Nora, Erika Huijser, Marjan A. Versnel, +4 more
9citations -
C1q-mediated steric hindrance limits FcγR contribution to antibody-driven phagocytosis by human neutrophils2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Monoclonal and Polyclonal Antibodies Research Open access
Max L.B. Grönloh, Lisanne de Vor, Seline A. Zwarthoff, Jana Venema, Rosemieke Smits, Stan Baijens, +7 more
0citations -
Serum complement component C1q levels in Quantiferon positive uveitis: improved stratification of high versus low risk active tuberculosis?2020 Investigative Ophthalmology & Visual Science article Medicine Ocular Diseases and Behçet’s Syndrome Open access
Benjamin Schrijver, Douwe J. Dijkstra, Nicole V. Borggreven, Rina La Distia Nora, Martin P. van Hagen, Simone A. Joosten, +2 more
0citations -
Fc Galactosylation Promotes Hexamerization of Human IgG1, Leading to Enhanced Classical Complement Activation2021 The Journal of Immunology article Medicine Monoclonal and Polyclonal Antibodies Research Open access cited by 1 patent
Thijs L. J. van Osch, Jan Nouta, Ninotska I. L. Derksen, Gerard van Mierlo, C. Ellen van der Schoot, Manfred Wuhrer, +2 more
88citations -
Long-term effects of combined B-cell immunomodulation with rituximab and belimumab in severe, refractory systemic lupus erythematosus: 2-year results2020 Nephrology Dialysis Transplantation article Medicine Systemic Lupus Erythematosus Research Open access
Tineke Kraaij, Eline J. Arends, Laura S. van Dam, Sylvia W.A. Kamerling, Paul L. A. van Daele, Obbo W Bredewold, +7 more
90citations -
Logic-gated antibody pairs that selectively act on cells co-expressing two antigens2022 Nature Biotechnology article Medicine Monoclonal and Polyclonal Antibodies Research Open access cited by 7 patents
Simone C. Oostindie, Derek A. Rinaldi, Gijs G. Zom, Michael J. Wester, Desiree Paulet, Kusai Al-Tamimi, +14 more
49citations -
The role of complement activation in autoimmune liver disease2020 Autoimmunity Reviews article Medicine Liver Diseases and Immunity Open access cited by 1 patent
Maaike Biewenga, Arantza Fariña Sarasqueta, Maarten E. Tushuizen, Eveline S. M. de Jonge‐Muller, Bart van Hoek, Leendert Adrianus Trouw
35citations -
P127 Long-term effects of combined B-cell immunomodulation with rituximab and belimumab in severe, refractory SLE: two year results rituximab and belimumab combination for severe SLE2020 Poster presentations conference-abstract Medicine Systemic Lupus Erythematosus Research Open access
Tineke Kraaij, Eline J. Arends, Laura S. van Dam, Sylvia W.A. Kamerling, Paul L. A. van Daele, Obbo W Bredewold, +7 more
3citations -
Successful pharmacological intervention at different levels of the complement system in an in vitro complement fixation model for bullous pemphigoid
Jenny Giang, Martijn B. A. van Doorn, Gilles F.H. Diercks, Santiago Rodrı́guez de Córdoba, Thierry P. P. van den Bosch, Marco W.J. Schreurs, +2 more
3citations -
Classical Monocyte-Derived and Lipid-Associated TREM2+ Macrophages Orchestrate Inflammatory and Fibrotic Processes in ANCA-Associated Glomerulonephritis2023 Journal of the American Society of Nephrology conference-abstract Medicine Vasculitis and related conditions
Yosta Vegting, Aldo Jongejan, Annette E. Neele, Nike Claessen, Jesper Kers, Joris J. T. H. Roelofs, +7 more
0citations -
Placental Complement Activation in Fetal and Neonatal Alloimmune Thrombocytopenia: An Observational Study2021 International Journal of Molecular Sciences article Medicine Blood groups and transfusion Open access
Thijs W. de Vos, Dian Winkelhorst, Hans J. Baelde, Kyra L. Dijkstra, Rianne D. M. van Bergen, Lotte E. van der Meeren, +13 more
23citations