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Optimism in inclusion body myositis: a double-blind randomised controlled phase III trial investigating the effect of sirolimus on disease progression in patients with IBM as measured by the IBM Functional Rating Scale2025 Clinical and Experimental Rheumatology article Medicine Inflammatory Myopathies and Dermatomyositis Open access
Umesh A. Badrising, Robert D. Henderson, Stephen Reddel, Alastair J. Corbett, Christina Liang, Katrina A. Reardon, +28 more
3citations -
Intensity- and time-matched acute interval and continuous endurance exercise similarly induce an anti-inflammatory environment in recreationally active runners: focus on PD-1 expression in Tregs and the IL-6/IL-10 axis2023 European Journal of Applied Physiology article Medicine Exercise and Physiological Responses Open access
Sebastian Proschinger, Alexander Schenk, Inga Weßels, Lars Donath, Ludwig Rappelt, Alan J. Metcalfe, +1 more
13citations -
Multimodal single-cell profiling reveals crosstalk between macrophages and stromal cells in poor prognostic cholangiocarcinoma patients2026 npj Precision Oncology article Medicine Cholangiocarcinoma and Gallbladder Cancer Studies Open access
Lara Rosaline Heij, Sikander Hayat, Konrad Reichel, Sidrah Maryam, Colm J. O’Rourke, Xiuxiang Tan, +27 more
3citations -
Multimodal single-cell profiling reveals cancer crosstalk between macrophages and stromal cells in poor prognostic cholangiocarcinoma patients2024 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Cholangiocarcinoma and Gallbladder Cancer Studies Open access
Lara Rosaline Heij, Sikander Hayat, Konrad Reichel, Sidrah Maryam, Colm J. O’Rourke, Xiuxiang Tan, +22 more
0citations -
Functional analysis reveals driver cooperativity and novel mechanisms in endometrial carcinogenesis2023 EMBO Molecular Medicine article Medicine Endometrial and Cervical Cancer Treatments Open access
Matthew Brown, Alicia Leon, Katarzyna Kedzierska, C. Moore, Hayley L. Belnoue-Davis, Susanne Flach, +6 more
5citations -
DuoHexaBody-CD37®, a novel biparatopic CD37 antibody with enhanced Fc-mediated hexamerization as a potential therapy for B-cell malignancies2020 Blood Cancer Journal article Medicine Monoclonal and Polyclonal Antibodies Research Open access cited by 5 patents
Simone C. Oostindie, Hilma J. van der Horst, Laurens P. Kil, Kristin Strumane, Marije B. Overdijk, Edward N. van den Brink, +12 more
71citations -
The influenza hemagglutinin stem antibody CR9114: Evidence for a narrow evolutionary path towards universal protection2022 Frontiers in Virology article Medicine Influenza Virus Research Studies Open access cited by 1 patent
Anna L. Beukenhorst, Jacopo Frallicciardi, Clarissa M. Koch, Jaco M. Klap, Angela M. Phillips, Michael M. Desai, +5 more
18citations -
Neutralizing antibodies elicited by the Ad26.COV2.S COVID-19 vaccine show reduced activity against 501Y.V2 (B.1.351), despite protection against severe disease by this variant2021 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine SARS-CoV-2 and COVID-19 Research Open access
Penny L. Moore, Thandeka Moyo-Gwete, Tandile Hermanus, Prudence Kgagudi, Frances Ayres, Zanele Makhado, +9 more
16citations -
Isotype conversion of Staphylococcal-specific IgG into IgM broadens the reactivity to other bacterial pathogens2025 Cell Reports Medicine article Medicine Monoclonal and Polyclonal Antibodies Research Open access
Remy M. Muts, Astrid Hendriks, Josefien W. Hommes, Max L.B. Grönloh, Douwe J. Dijkstra, Carla J. C. de Haas, +9 more
0citations -
Renal inflamm-aging provokes intra-graft inflammation following experimental kidney transplantation2022 American Journal of Transplantation article Medicine Renal Transplantation Outcomes and Treatments Open access cited by 6 patents
An He, Attia Sarwar, Linda Marie Laura Thole, Janine Siegle, Arne Sattler, Muhammad Ashraf, +11 more
28citations