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Healthy volunteers in first‐in‐human oncology drug development for small molecules2021 British Journal of Clinical Pharmacology article Mathematics Statistical Methods in Clinical Trials Open access
Begoña de las Heras, Dalila Bouyoucef‐Cherchalli, Lesley Reeve, Andreas Reichl, Debra Mandarino, Stephen D. Flach, +3 more
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A first step towards best practice recommendations for the design and statistical analyses of pragmatic clinical trials: A modified Delphi approach2022 British Journal of Clinical Pharmacology article Mathematics Statistical Methods in Clinical Trials Open access
Victoria Palin, Tjeerd Pieter van Staa, Stephanie Steels, Andrea B. Troxel, Rolf H. H. Groenwold, Thomas MacLennan MacDonald, +7 more
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Sentinel dosing: A proposed algorithm to guide decision making on which cohorts in early phase clinical pharmacology trials should use this approach2025 British Journal of Clinical Pharmacology article Mathematics Statistical Methods in Clinical Trials Open access
Jules A. A. C. Heuberger, Perry de Jongh, Ewoud‐Jan van Hoogdalem, Wim J. Tamminga, Pieter de Graeff, Geert Jan Groeneveld
4citations -
Dose escalations in phase I studies: Feasibility of interpreting blinded pharmacodynamic data2022 British Journal of Clinical Pharmacology article Mathematics Statistical Methods in Clinical Trials Open access
Gerardus J. Hassing, Michiel Joost van Esdonk, Gerard J. P. van Westen, Adam F. Cohen, Jacobus Burggraaf, Pim Gal
2citations
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