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Accelerating vaccine trial conduct in a pandemic with a hot spot‐based inclusion strategy using trial and epidemic simulation2021 Clinical and Translational Science article Mathematics Statistical Methods in Clinical Trials Open access
Johan L. van der Plas, Michiel Joost van Esdonk, Ingrid M. C. Kamerling, Adam F. Cohen
7citations -
A Pharmacometrics‐Informed Trial Simulation Framework for Optimizing Study Designs for Disease‐Modifying Treatments in Rare Neurological Disorders2025 CPT Pharmacometrics & Systems Pharmacology article Mathematics Statistical Methods in Clinical Trials Open access
Yevgen V. Ryeznik, R.-D Hilgers, Nicole Maria Heussen, Emmanuelle Comets, France Mentré, Niels Hendrickx, +7 more
3citations -
Methodological Challenges of Emulating a Target Trial to Assess Effectiveness of Timing of PCSK9 Inhibitor Treatment Initiation Post Myocardial Infarction2026 Pharmacoepidemiology and Drug Safety article Mathematics Advanced Causal Inference Techniques Open access
Thomas Cars, Stefan Gustafsson, Queenie M Chan, Nafeesa N Dhalwani, Shia T. Kent, Chris P Gale, +7 more
0citations -
Healthy volunteers in first‐in‐human oncology drug development for small molecules2021 British Journal of Clinical Pharmacology article Mathematics Statistical Methods in Clinical Trials Open access
Begoña de las Heras, Dalila Bouyoucef‐Cherchalli, Lesley Reeve, Andreas Reichl, Debra Mandarino, Stephen D. Flach, +3 more
18citations -
Estimating individualized treatment effects from randomized controlled trials: a simulation study to compare risk-based approaches2023 BMC Medical Research Methodology article Mathematics Advanced Causal Inference Techniques Open access
Alexandros Rekkas, Peter R. Rijnbeek, David M. Kent, Ewout Willem Steyerberg, David V. Klaveren
14citations -
Individualized treatment effect was predicted best by modeling baseline risk in interaction with treatment assignment2022 arXiv (Cornell University) preprint Mathematics Statistical Methods in Clinical Trials Open access
Alexandros Rekkas, Peter R. Rijnbeek, David M. Kent, Ewout Willem Steyerberg, David V. Klaveren
0citations -
Ordinal outcome analysis improves the detection of between-hospital differences in outcome2021 BMC Medical Research Methodology article Mathematics Statistical Methods in Clinical Trials Open access
Iris E. Ceyisakar, Nikki van Leeuwen, Diederik W.J. Dippel, Ewout Willem Steyerberg, Hester Floor Lingsma
23citations