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Papers matching “minimal clinically important difference” 6

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The difference between statistical significance and clinical relevance. The case of minimal important change, non-inferiority trials, and smallest worthwhile effect
2023 Injury article Mathematics Statistical Methods in Clinical Trials Open access

Nienke Willemien Willigenburg, Rudolf Wilhelm Poolman

42

citations
Ordinal outcomes add value to clinical trials
2023 The Lancet article Mathematics Statistical Methods in Clinical Trials Open access

Frederikus A. Klok, Bob Siegerink

0

citations
Blueprint for mechanistic, data‐rich early phase clinical pharmacology studies in dermatology
2020 British Journal of Clinical Pharmacology article Mathematics Statistical Methods in Clinical Trials Open access

Robert Rißmann, Matthijs Moerland, Martijn B. A. van Doorn

13

citations
De‐risking Clinical Trials: The BIAL Phase I Trial in Foresight
2021 Clinical Pharmacology & Therapeutics article Mathematics Statistical Methods in Clinical Trials Open access

Adam F. Cohen, Jeroen van Smeden, David John Webb

10

citations
The Changing Face of Oncology Research, Drug Development, and Clinical Practice: Toward Patient‐Focused Precision Therapeutics
2020 Clinical Pharmacology & Therapeutics article Mathematics Statistical Methods in Clinical Trials Open access

Karthik Venkatakrishnan, Piet H. van der Graaf, Sarah A. Holstein

4

citations
A comparison of hyperparameter tuning procedures for clinical prediction models: A simulation study
2024 Statistics in Medicine article Mathematics Statistical Methods and Inference Open access

Zoë S Dunias, Ben Van Calster, Dirk Timmerman, Anne‐Laure Boulesteix, Maarten van Smeden

35

citations

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