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Dose escalations in phase I studies: Feasibility of interpreting blinded pharmacodynamic data2022 British Journal of Clinical Pharmacology article Mathematics Statistical Methods in Clinical Trials Open access
Gerardus J. Hassing, Michiel Joost van Esdonk, Gerard J. P. van Westen, Adam F. Cohen, Jacobus Burggraaf, Pim Gal
2citations -
Tell me what you want, what you really really want: Estimands in observational pharmacoepidemiologic comparative effectiveness and safety studies2023 Pharmacoepidemiology and Drug Safety article Mathematics Statistical Methods in Clinical Trials Open access
Kim Luijken, Rik van EEKELEN, Helga Gardarsdóttir, Rolf H. H. Groenwold, Nan van Geloven
21citations -
Maximizing Treatment Opportunities: Assessing Protocol Waivers’ Impact on Safety and Outcome in the Drug Rediscovery Protocol2024 Clinical Cancer Research article Mathematics Statistical Methods in Clinical Trials Open access
Jade M. van Berge Henegouwen, Laurien Joanna Zeverijn, Birgit S. Geurts, Louisa Rose Hoes, Hanneke van der Wijngaart, Vincent van der Noort, +7 more
2citations -
Drug exposure misclassification in pharmacoepidemiology: Sources and relative impact2021 Pharmacoepidemiology and Drug Safety article Mathematics Statistical Methods in Epidemiology Open access
Mirjam Hempenius, Rolf H. H. Groenwold, Anthonius de Boer, Olaf H. Klungel, Helga Gardarsdóttir
36citations -
A novel cardiovascular systems model to quantify drugs effects on the inter‐relationship between contractility and other hemodynamic variables2022 CPT Pharmacometrics & Systems Pharmacology article Mathematics Statistical Methods in Clinical Trials Open access
Yu Fu, Hadi Taghvafard, Medhat M. Said, Eric I. Rossman, Teresa A. Collins, Stéphanie Billiald‐Desquand, +4 more
10citations -
The Changing Face of Oncology Research, Drug Development, and Clinical Practice: Toward Patient‐Focused Precision Therapeutics2020 Clinical Pharmacology & Therapeutics article Mathematics Statistical Methods in Clinical Trials Open access
Karthik Venkatakrishnan, Piet H. van der Graaf, Sarah A. Holstein
4citations -
Sentinel dosing: A proposed algorithm to guide decision making on which cohorts in early phase clinical pharmacology trials should use this approach2025 British Journal of Clinical Pharmacology article Mathematics Statistical Methods in Clinical Trials Open access
Jules A. A. C. Heuberger, Perry de Jongh, Ewoud‐Jan van Hoogdalem, Wim J. Tamminga, Pieter de Graeff, Geert Jan Groeneveld
4citations
18 results