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Multi-stakeholder sessions on major innovation topics in rare disease clinical trials2024 Orphanet Journal of Rare Diseases article Mathematics Statistical Methods in Clinical Trials Open access
Daniel Bodden, Stefanie Schoenen, Stephanie Wied, Johan Verbeeck, Maya Dirani, Nicole Maria Heussen, +3 more
3citations -
Adaptive sample size determination for the development of clinical prediction models2021 Diagnostic and Prognostic Research article Mathematics Statistical Methods in Epidemiology Open access
Evangelia Christodoulou, Maarten van Smeden, Michael Edlinger, Dirk Timmerman, Maria M. Wanitschek, Ewout Willem Steyerberg, +1 more
38citations -
How to develop, validate, and update clinical prediction models using multinomial logistic regression2024 Journal of Clinical Epidemiology article Mathematics Statistical Methods in Epidemiology Open access
Celina K Gehringer, Glen Philip Martin, Ben Van Calster, Kimme Leanne Hyrich, Suzanne M. M. Verstappen, Jamie C. Sergeant
20citations -
The impact of allocation bias on test decisions in clinical trials with multiple endpoints using multiple testing strategies2024 BMC Medical Research Methodology article Mathematics Statistical Methods in Clinical Trials Open access
Stefanie Schoenen, Nicole Maria Heussen, Johan Verbeeck, R.-D Hilgers
6citations -
Understanding overfitting in random forest for probability estimation: a visualization and simulation study2024 Diagnostic and Prognostic Research article Mathematics Statistical Methods and Inference Open access
Lasai Barreñada, Paula Dhiman, Dirk Timmerman, Anne‐Laure Boulesteix, Ben Van Calster
149citations -
Estimating uncertainty when providing individual cardiovascular risk predictions: a Bayesian survival analysis2024 Journal of Clinical Epidemiology article Mathematics Statistical Methods in Epidemiology Open access
Steven H J Hageman, Frank L.J. Visseren, John William McEvoy, J. Wouter Jukema, Yvo M. Smulders, Maarten van Smeden, +1 more
4citations -
A Pharmacometrics‐Informed Trial Simulation Framework for Optimizing Study Designs for Disease‐Modifying Treatments in Rare Neurological Disorders2025 CPT Pharmacometrics & Systems Pharmacology article Mathematics Statistical Methods in Clinical Trials Open access
Yevgen V. Ryeznik, R.-D Hilgers, Nicole Maria Heussen, Emmanuelle Comets, France Mentré, Niels Hendrickx, +7 more
3citations