Targeting cognitive control and affective processing in aggression: neuromodulation approaches in CRC/TRR 379
Abstract
Interventions aimed at reducing aggression in mental disorders remain insufficiently addressed by current research, despite the substantial individual and societal burden associated with aggressive behavior. Consequently, strategies for modulating aggressive behavior are of high clinical relevance but are not yet adequately represented in the currently available intervention approaches. The Collaborative Research Center (CRC) TRR 379 is dedicated to exploring the modulation of aggressive behavior through neuromodulation. Four projects employ complementary methodologies to investigate whether neural systems involved in cognitive control and affect regulation can be modulated to reduce aggressive behavior in patients with mental disorders and violent offenders. These techniques include transcranial direct current stimulation, low-intensity focused transcranial ultrasound stimulation, and real-time functional magnetic resonance imaging (fMRI) neurofeedback. Through these multimodal approaches, the projects aim to advance the understanding of the modifiability of aggressive behavior, identify factors that contribute to successful neuromodulation, and support the development of individualized interventions.
Authors 9
-
Carmen Weidler corresponding Aachen Institute of Translational Neuroscience and Clinical Psychology Faculty of Medicine
Affiliation as printed
Institute of Translational Neuroscience and Clinical Psychology, Faculty of Medicine, RWTH Aachen University, Pauwelsstraße 30, 52074, Aachen, Germany. cweidler@ukaachen.de
-
Johannes Gutenberg University Mainz · University Medical Center of the Johannes Gutenberg University Mainz · Saarland University
Affiliation as printed
Department of Psychiatry and Psychotherapy, University Medical Center, Johannes Gutenberg University, Mainz, Germany
Institute for Forensic Psychology and Psychiatry, Saarland University, Homburg, Germany
-
Johannes Gutenberg University Mainz · University Medical Center of the Johannes Gutenberg University Mainz
Affiliation as printed
Department of Psychiatry and Psychotherapy, University Medical Center, Johannes Gutenberg University, Mainz, Germany
-
Johannes Gutenberg University Mainz · University Medical Center of the Johannes Gutenberg University Mainz
Affiliation as printed
Department of Psychiatry and Psychotherapy, University Medical Center, Johannes Gutenberg University, Mainz, Germany
-
Affiliation as printed
Department of Psychiatry, Psychotherapy and Psychosomatics, Faculty of Medicine, RWTH Aachen University, 52074, Aachen, Germany
-
Heidelberg University · Central Institute of Mental Health · Medizinische Fakultät Mannheim · Deutsches Zentrum für Psychische Gesundheit
Affiliation as printed
Department of Psychosomatic Medicine and Psychotherapy, Central Institute of Mental Health, Medical Faculty, Mannheim/Heidelberg University, Mannheim, Germany
German Center for Mental Health, Partner Site Mannheim-Heidelberg-Ulm, Heidelberg, Germany
-
Goethe University Frankfurt · University Hospital Frankfurt
Affiliation as printed
University Hospital Frankfurt, Department of Psychiatry, Psychosomatic Medicine and Psychotherapy, Goethe University Frankfurt, Frankfurt, Germany
-
Goethe University Frankfurt · University Hospital Frankfurt
Affiliation as printed
University Hospital Frankfurt, Department of Psychiatry, Psychosomatic Medicine and Psychotherapy, Goethe University Frankfurt, Frankfurt, Germany
-
Jana Zweerings Aachen Department of Psychiatry, Psychotherapy and Psychosomatics Faculty of Medicine
Affiliation as printed
Department of Psychiatry, Psychotherapy and Psychosomatics, Faculty of Medicine, RWTH Aachen University, 52074, Aachen, Germany