Standardising Epigenetic Data Analysis: A Prerequisite for Regulatory Uptake in Environmental Risk Assessment

Zenodo (CERN European Organization for Nuclear Research)

Abstract

Recent advances in sequencing technologies have enabled the rapid generation of epigenomic datasets across ecotoxicologically relevant species. DNA methylation, histone modifications, and non-coding RNAs are increasingly investigated as potential biomarkers for environmental monitoring and next-generation environmental risk assessment (NGERA). However, the limited availability of standardized bioinformatic workflows currently represents one of the largest barriers to reproducibility, comparability, and regulatory acceptance of epigenetic evidence.

Authors 10

1. Jana Asselman

   Ghent University

   Affiliation as printed

   Blue Growth Research Lab, Ghent University, Belgium

2. Mercedes Blázquez

   Consejo Superior de Investigaciones Científicas · Institut de Ciències del Mar

   Affiliation as printed

   Instituto de Ciencias del Mar (ICM-CSIC)

3. Hollie Marshall

   University of Leicester

   Affiliation as printed

   University of Leicester

4. Jan Alexander Mennigen

   University of Ottawa

   Affiliation as printed

   Department of Biology, University of Ottawa, Canada

5. Anna Navarro

   ZeClinics (Spain)

   Affiliation as printed

   ZeClinics (Spain)

6. Laia Navarro‐Martín

   Institute of Environmental Assessment and Water Research

   Affiliation as printed

   Institute of Environmental Assessment and Water Research

7. Albano Pinto

   University of Aveiro

   Affiliation as printed

   University of Aveiro

8. Eduarda M. Santos

   University of Exeter

   Affiliation as printed

   University of Exeter

9. Camilo Escobar-Sierra Aachen

   RWTH Aachen University

   Affiliation as printed

   RWTH Aachen University

   Hidrobilógica SAS

10. Joana Luísa Pereira

    University of Aveiro

    Affiliation as printed

    University of Aveiro