Hemiplegic migraine: genetics and pathophysiology

• Widespread brain parenchymal HMGB1 and NF-κB neuroinflammatory responses upon cortical spreading depolarization in familial hemiplegic migraine type 1 mice

  2021 Neurobiology of Disease article Medicine Migraine and Headache Studies Open access

  41

  citations
• Optogenetic cortical spreading depolarization induces headache-related behaviour and neuroinflammatory responses some prolonged in familial hemiplegic migraine type 1 mice

  2023 The Journal of Headache and Pain article Medicine Migraine and Headache Studies Open access

  24

  citations
• Spontaneous and optogenetically induced cortical spreading depolarization in familial hemiplegic migraine type 1 mutant mice

  2024 Neurobiology of Disease article Medicine Migraine and Headache Studies Open access

  18

  citations
• CaV2.1 channel mutations causing familial hemiplegic migraine type 1 increase the susceptibility for cortical spreading depolarizations and seizures and worsen outcome after experimental traumatic brain injury

  2022 eLife article Medicine Traumatic Brain Injury and Neurovascular Disturbances Open access

  17

  citations
• Whole Exome Sequencing of Hemiplegic Migraine Patients Shows an Increased Burden of Missense Variants in CACNA1H and CACNA1I Genes

  2023 Molecular Neurobiology article Medicine Migraine and Headache Studies Open access

  16

  citations
• Responsivity to light in familial hemiplegic migraine type 1 mutant mice reveals frequency‐dependent enhancement of visual network excitability

  2020 European Journal of Neuroscience article Medicine Migraine and Headache Studies Open access

  13

  citations
• Spontaneous spreading depolarizations originate subcortically in a novel mouse model of familial hemiplegic migraine type 2

  2024 Neurobiology of Disease article Medicine Migraine and Headache Studies Open access

  9

  citations
• Genetics of migraine: Delineation of contemporary understanding of the genetic underpinning of migraine

  2023 Handbook of clinical neurology book-chapter Medicine Migraine and Headache Studies

  9

  citations
• Brainstem depolarization–induced lethal apnea associated with gain-of-function SCN1A L263V is prevented by sodium channel blockade

  2024 Proceedings of the National Academy of Sciences article Biochemistry, Genetics and Molecular Biology Ion channel regulation and function Open access

  7

  citations

9 results