Additional file 4 of A rare missense variant impacting NEK1 kinase function is associated with ALS

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Abstract

Supplementary Material 4. Fig. 4 The p.N598S variant does not impact the interaction of NEK1 with C21orf2. Co-immunoprecipitation performed in HEK cells overexpressing either NEK1-WT or p.N598S. The levels of C21orf2 interacting with NEK1 are comparable in both groups.Mean ± SD of n = 3 independent experiments.

Authors 31

1. Dávid Brenner

   German Center for Neurodegenerative Diseases · Universität Ulm · University Hospital Ulm

   Affiliation as printed

   University Hospital Ulm

   German Center for Neurodegenerative Diseases

   University of Ulm

2. Anna Ponomarenko

   Universität Ulm

   Affiliation as printed

   University of Ulm

3. Iris Petrut

   Universität Ulm

   Affiliation as printed

   University of Ulm

4. Sofia Beyrle

   Universität Ulm

   Affiliation as printed

   University of Ulm

5. Matilde Contardo

   KU Leuven · VIB-KU Leuven Center for Brain & Disease Research

   Affiliation as printed

   VIB-KU Leuven Center for Brain & Disease Research

   KU Leuven

6. Isabel Loss

   University Hospital Ulm

   Affiliation as printed

   University Hospital Ulm

7. Constantin Radke Aachen

   Universitätsklinikum Aachen

   Affiliation as printed

   Universitätsklinikum Aachen

8. Jonas Frank

   University of Augsburg

   Affiliation as printed

   University of Augsburg

9. Eleni Zimmer

   Universität Ulm

   Affiliation as printed

   University of Ulm

10. Matthias Schlesner

    University of Augsburg

    Affiliation as printed

    University of Augsburg

11. Pascal Achenbach Aachen

    Universitätsklinikum Aachen

    Affiliation as printed

    Universitätsklinikum Aachen

12. Wendy Scheveneels

    KU Leuven · VIB-KU Leuven Center for Brain & Disease Research

    Affiliation as printed

    VIB-KU Leuven Center for Brain & Disease Research

    KU Leuven

13. Amr Aly

    Johns Hopkins University · Universität Ulm

    Affiliation as printed

    Johns Hopkins University

    University of Ulm

14. Hülya Nazlican

    Alfried Krupp Hospital

    Affiliation as printed

    Alfried Krupp Hospital

15. Jasper Hesebeck-Brinkmann

    University Hospital Ulm

    Affiliation as printed

    University Hospital Ulm

16. Patrick Oeckl

    German Center for Neurodegenerative Diseases · University Hospital Ulm

    Affiliation as printed

    University Hospital Ulm

    German Center for Neurodegenerative Diseases

17. Kathrin Müller

    University Hospital Ulm

    Affiliation as printed

    University Hospital Ulm

18. Reiner Siebert

    Universität Ulm

    Affiliation as printed

    University of Ulm

19. Tobias Böckers

    German Center for Neurodegenerative Diseases · Universität Ulm

    Affiliation as printed

    German Center for Neurodegenerative Diseases

    University of Ulm

20. Kristel van Eijk

    Utrecht University

    Affiliation as printed

    Utrecht University

21. Jan Herman Veldink

    Utrecht University

    Affiliation as printed

    Utrecht University

22. Alexander Kleger

    Universität Ulm

    Affiliation as printed

    University of Ulm

23. Medhanie Mulaw

    Universität Ulm

    Affiliation as printed

    University of Ulm

24. Peter Munch Andersen

    Umeå University

    Affiliation as printed

    Umeå University

25. Karin Forsberg

    Umeå University

    Affiliation as printed

    Umeå University

26. Jochen H. Weishaupt

    German Center for Neurodegenerative Diseases · Universität Ulm · University Hospital Ulm

    Affiliation as printed

    University Hospital Ulm

    German Center for Neurodegenerative Diseases

    University of Ulm

27. Seyed Babak Loghmani

    University Hospital Ulm

    Affiliation as printed

    University Hospital Ulm

28. Thorsten Grehl

    Alfried Krupp Hospital

    Affiliation as printed

    Alfried Krupp Hospital

29. Philip Van Damme

    KU Leuven · Universitair Ziekenhuis Leuven

    Affiliation as printed

    Universitair Ziekenhuis Leuven

    KU Leuven

30. Joachim Weis Aachen

    Universitätsklinikum Aachen

    Affiliation as printed

    Universitätsklinikum Aachen

31. Alberto Catanese Aachen

    RWTH Aachen University · German Center for Neurodegenerative Diseases · Universität Ulm

    Affiliation as printed

    RWTH Aachen University

    German Center for Neurodegenerative Diseases

    University of Ulm