Using monophasic potential mapping to visualize the Brugada substrate

Heart Rhythm, vol. 23, pp. e2598–e2600

Abstract

Identifying treatment targets during ablation procedures for Brugada syndrome often requires provocation tests,1 which induce functional conduction block2 and excitation failure in structurally discontinuous subepicardial myocardium.3,4 Sites of excitation failure lack a clear moment of local activation, making them difficult to identify using conventional electrogram analysis. In other cardiac conditions, functional conduction block has been shown to depend on the direction by which an activation front reaches an affected area.

Authors 3

1. Mark G. Hoogendijk corresponding

   Erasmus MC

   Affiliation as printed

   Department of Cardiology, Cardiovascular Institute, Thorax Center, Erasmus MC, Rotterdam, The Netherlands. Electronic address: m.hoogendijk@erasmusmc.nl

2. Sing‐Chien Yap

   Erasmus MC

   Affiliation as printed

   Department of Cardiology, Cardiovascular Institute, Thorax Center, Erasmus MC, Rotterdam, The Netherlands

3. Bastiaan J. Boukens Aachen

   Maastricht University · Leiden University Medical Center · Maastricht University Medical Centre

   Affiliation as printed

   Department of Physiology, Cardiovascular Research Institute Maastricht, Maastricht University Medical Center, Maastricht, The Netherlands; Laboratory of Experimental Cardiology, Department of Cardiology, LUMC, Leiden, The Netherlands