Development of a questionnaire for oxygen therapy effectiveness (QuOTE)

Abstract

Background: Despite the many clinical benefits of long-term oxygen therapy (LTOT) for chronic respiratory diseases, patient-reported LTOT outcome measures are lacking. We therefore developed the Questionnaire for Oxygen Therapy Effectiveness (QuOTE). Methods: Delphi methodology was used by a group of European clinical and academic respiratory specialists to identify domains & questions to include in an LTOT effectiveness tool. The survey was then beta-tested by a group of LTOT patients. erj;66/suppl_69/PA2429/F1 F1 F1 Results: In the first round, 13 clinical & academic respiratory clinicians agreed the domains to include. Questions covered physical activity, dyspnea, sleep quality, mental clarity, LTOT side effects & equipment. Advantages & disadvantages of current tools, clinical assessment priorities for patient & clinician and the caveats & advantages around length were discussed. Over 6 months, 3 rounds of Delphi consensus method distilled 18 questions to 9 (Figure). All beta testers reported the survey was easy to read, understand and complete. Conclusion: The QuOTE is a new tool to assess the effectiveness of LTOT. It will require further testing for reliability, construct & face validity and responsiveness. We are working on French, German, Spanish, Portuguese & Chinese versions. Follow-up studies are needed to test it against outcomes and other physiological assessments. Our goal is to improve the assessment & outcomes of respiratory patients receiving LTOT.

Authors 12

1. Michael Dreher Aachen 1Department of Pneumology and Intensive Care Medicine

   Universitätsklinikum Aachen

   Affiliation as printed

   1Department of Pneumology and Intensive Care Medicine, University Hospital Aachen, Aachen, Germany

2. Vogelmeier Claus

   Universitätsklinikum Gießen und Marburg

   Affiliation as printed

   2University Hospital Marburg, Marburg, Germany

3. Gilles Jébrak
   Affiliation as printed

   3University Hospital Paris Nord Val de Seine, Paris, France

4. Claudio A. Rabec

   Centre Hospitalier Universitaire Vaudois

   Affiliation as printed

   4Lausanne University Hospital, Lausanne, Switzerland

5. Peter Jan Wijkstra

   University Medical Center Groningen

   Affiliation as printed

   5University Medical Center Groningen, Groningen, Netherlands

6. Maxime Patout
   Affiliation as printed

   6Rouen University Hospital, Rouen, France

7. Javier Sayas Catalán

   Hospital Universitario 12 De Octubre

   Affiliation as printed

   7Hospital Universitario 12 de Octubre, Madrid, Spain

8. Capucine Morélot‐Panzini

   Pitié-Salpêtrière Hospital

   Affiliation as printed

   8Hôpital La Pitié Salpêtrière, Paris, France

9. João Carlos Winck

   Universidade do Porto

   Affiliation as printed

   9University of Porto, Porto, Portugal

10. Klaas Frederik Franzen

    University of Lübeck

    Affiliation as printed

    11University of Luebeck, Luebeck, Germany

11. David Halpin

    University of Exeter

    Affiliation as printed

    12University of Exeter, Exeter, United Kingdom

12. Nicholas Hart

    King's College London

    Affiliation as printed

    13King's College London, London, United Kingdom