Transcutaneous conditioning electrical stimulation alters the cold detection threshold

Journal of Neurophysiology, vol. 134, pp. 1727–1732

Abstract

A novel approach is evaluated for probing peripheral cold-sensing fiber by using electrical stimulation's large variety of protocols in combination with activation of the fiber by thermal stimulation to ensure selective activation of the cold-sensing fibers. The results showed that the cold detection threshold could be altered by electrical stimulation, but no significant differences were found for warm temperatures or different frequencies of conditioning electrical stimulation. The result was promising, but further studies are needed.

Authors 3

1. Ken Steffen Frahm

   Aalborg University

   Affiliation as printed

   Aalborg University

   Integrative Neuroscience group, Center for Neuroplasticity and Pain (CNAP), Department of Health Science and Technology, Aalborg University, Aalborg, Denmark

2. Carsten Dahl Mørch

   Aalborg University

   Affiliation as printed

   Aalborg University

   Integrative Neuroscience group, Center for Neuroplasticity and Pain (CNAP), Department of Health Science and Technology, Aalborg University, Aalborg, Denmark

3. Jenny Tigerholm corresponding Aachen Joint Research Centre for Computational Biomedicine (JRC-COMBINE) Scientific Center for Neuropathic Pain Aachen SCNAACHEN

   RWTH Aachen University · Universitätsklinikum Aachen · Aalborg University

   Affiliation as printed

   Aalborg University

   RWTH Aachen

   Uniklinik RWTH

   Integrative Neuroscience group, Center for Neuroplasticity and Pain (CNAP), Department of Health Science and Technology, Aalborg University, Aalborg, Denmark

   Joint Research Center for Computational Biomedicine, RWTH Aachen, Aachen, Germany

   Scientific Center for Neuropathic pain Aachen SCNAACHEN, Uniklinik RWTH, Aachen, Germany