Modulation of poststroke motor cortex activity by metaplasticity-inducted theta burst stimulation: A concurrent TMS-EEG study

Brain stimulation, vol. 18, pp. 1883–1886

Abstract

Metaplasticity is a high-level form of plasticity mechanism which describes how prior neuronal activity level mediates subsequent Hebbian-type synaptic plasticity induction, that is, long-term depression (LTD) or long-term potentiation (LTP) [1]. The pairing of two non-identical repetitive transcranial magnetic stimulation (rTMS) protocols could enlarge after-effects (either LTP- or LTD-like) in human primary motor cortex (M1) presumably via metaplastic mechanisms. The pairing protocol is called priming stimulation, or metaplasticity-inducted stimulation [1,2].

Authors 8

1. Jiaqi Zhang corresponding

   Hong Kong Polytechnic University

   Affiliation as printed

   Department of Rehabilitation Sciences, The Hong Kong Polytechnic University, Hong Kong Special Administrative Region of China. Electronic address: jack-jiaqi.zhang@polyu.edu.hk

   Department of Rehabilitation Sciences, The Hong Kong Polytechnic University, Hong Kong SAR, China. Electronic address: jack-jiaqi.zhang@polyu.edu.hk

2. Rong Zeng

   Hong Kong Polytechnic University

   Affiliation as printed

   Department of Rehabilitation Sciences, The Hong Kong Polytechnic University, Hong Kong Special Administrative Region of China

   Department of Rehabilitation Sciences, The Hong Kong Polytechnic University, Hong Kong SAR, China

3. Zhongfei Bai

   Tongji University · Shanghai Sunshine Rehabilitation Center

   Affiliation as printed

   Department of Neurology and Neurorehabilitation, Shanghai YangZhi Rehabilitation Hospital, School of Medicine, Tongji University, Shanghai, China. Electronic address: zhongfei@tongji.edu.cn

4. Youxin Sui

   Hong Kong Polytechnic University

   Affiliation as printed

   Department of Rehabilitation Sciences, The Hong Kong Polytechnic University, Hong Kong Special Administrative Region of China

   Department of Rehabilitation Sciences, The Hong Kong Polytechnic University, Hong Kong SAR, China

5. Tommy L.H. Lam

   Hong Kong Polytechnic University

   Affiliation as printed

   University Research Facility in Behavioral and Systems Neuroscience, The Hong Kong Polytechnic University, Hong Kong Special Administrative Region of China

   University Research Facility in Behavioral and Systems Neuroscience, The Hong Kong Polytechnic University, Hong Kong SAR, China

6. David M. A. Mehler Aachen Department of Psychiatry, Psychotherapy and Psychosomatics

   University of Münster · Universitätsklinikum Aachen · RWTH Aachen University

   Affiliation as printed

   Department of Psychiatry, Psychotherapy and Psychosomatics, University Hospital RWTH Aachen, Aachen, Germany; Institute for Translational Psychiatry, University of Münster, Münster, Germany

7. Ulf Ziemann

   Hertie Institute for Clinical Brain Research · University of Tübingen

   Affiliation as printed

   Department of Neurology & Stroke and Hertie Institute for Clinical Brain Research, Eberhard-Karls-University Tübingen, Tübingen, Germany

8. Tommy Kwan Hin Fong

   Hong Kong Polytechnic University

   Affiliation as printed

   Department of Rehabilitation Sciences, The Hong Kong Polytechnic University, Hong Kong Special Administrative Region of China; Research Centre of Assistive Technology, The Hong Kong Polytechnic University, Hong Kong Special Administrative Region of China

   Department of Rehabilitation Sciences, The Hong Kong Polytechnic University, Hong Kong SAR, China; Research Centre of Assistive Technology, The Hong Kong Polytechnic University, Hong Kong SAR, China