Assembling, Priming, and Storing Circuits for Pediatric and Neonatal Extracorporeal Membrane Oxygenation

ASAIO Journal, vol. 72, pp. 249–254

Abstract

The storing of dry-assembled and primed extracorporeal membrane oxygenation (ECMO) circuits is common practice and endorsed by the Extracorporeal Life Support Organization (ELSO) for up to 30 days. We conducted an anonymous survey among chief perfusionists in German neonatal and pediatric ECMO centers to identify key parameters of the actual clinical practices. Ten of 15 (67%) participating centers do not pre-assemble and pre-prime circuits in apprehension of future patients. The average storing times in 33% of the centers exceed the ELSO recommended 30 days up to 150 days. Longer storing times may be the result of less annual cases compared with adult ECMO. The addition of concentrated erythrocytes in the priming fluid may be one reason for ad-hoc de-airing. None of the participating centers treats children exclusively, omitting the center's overall experience as reason for the different practices in adults and children. Nonetheless, the average time required for assembly and de-airing was extended by 40% compared with adult ECMO while the perceived urgency in emergency situations was increased. Overall, this study shows distinct differences between adult and neonatal/pediatric ECMO regarding circuit preassembly and prepriming that indicate the need for improved standard operating procedures and specific research.

Authors 9

1. Lasse J. Strudthoff corresponding Aachen Department of Cardiovascular Engineering Institute of Applied Medical Engineering Medical Faculty

   RWTH Aachen University

   Affiliation as printed

   Department of Cardiovascular Engineering, Institute of Applied Medical Engineering, Medical Faculty, RWTH Aachen University, Aachen, Germany

2. Christian Bleilevens Aachen Department of Anesthesiology, Medical Faculty

   Universitätsklinikum Aachen · RWTH Aachen University

   Affiliation as printed

   Department of Anesthesiology, Medical Faculty, University Hospital RWTH Aachen University, Aachen, Germany

3. Alexander Wallraff Aachen Department of Heart Surgery Medical Faculty

   Universitätsklinikum Aachen · RWTH Aachen University

   Affiliation as printed

   Department of Heart Surgery, Medical Faculty, University Hospital RWTH Aachen, Aachen, Germany

4. Johanna C. Clauser corresponding Aachen Department of Cardiovascular Engineering Institute of Applied Medical Engineering Medical Faculty

   RWTH Aachen University

   Affiliation as printed

   Department of Cardiovascular Engineering, Institute of Applied Medical Engineering, Medical Faculty, RWTH Aachen University, Aachen, Germany

5. Sebastian Victor Jansen corresponding Aachen Department of Cardiovascular Engineering Institute of Applied Medical Engineering Medical Faculty

   RWTH Aachen University

   Affiliation as printed

   Department of Cardiovascular Engineering, Institute of Applied Medical Engineering, Medical Faculty, RWTH Aachen University, Aachen, Germany

6. Marlene Schadow corresponding Aachen Department of Cardiovascular Engineering Institute of Applied Medical Engineering Medical Faculty

   RWTH Aachen University

   Affiliation as printed

   Department of Cardiovascular Engineering, Institute of Applied Medical Engineering, Medical Faculty, RWTH Aachen University, Aachen, Germany

7. Rolf Rossaint Aachen Department of Anesthesiology, Medical Faculty

   Universitätsklinikum Aachen · RWTH Aachen University

   Affiliation as printed

   Department of Anesthesiology, Medical Faculty, University Hospital RWTH Aachen University, Aachen, Germany

8. Rüdger Kopp Aachen Department of Intensive Care Medical Faculty

   Universitätsklinikum Aachen · RWTH Aachen University

   Affiliation as printed

   Department of Intensive Care, Medical Faculty, University Hospital RWTH Aachen University, Aachen, Germany

9. Patrick Winnersbach Aachen Department of Anesthesiology, Medical Faculty

   Universitätsklinikum Aachen · RWTH Aachen University

   Affiliation as printed

   Department of Anesthesiology, Medical Faculty, University Hospital RWTH Aachen University, Aachen, Germany