Clostridioides difficile is a bacterial priority pathogen
Anaerobe, vol. 93, pp. 102965
Abstract
Figure illustrating that considering mortality, burden, treatment failure, epidemiology, antimicrobial resistance and current/future treatment modalities [icons from left to right], C. difficile [depicted as a red petritrichous flaggelated bacterium] should be considered a priority pathogen [needle pointing to the red area]. • Clostridioides difficile infections are associated with significant mortality and economic burden. • New epidemic types of C. difficile are emerging. • Community-acquired CDI is increasing and poorly understood. • Reduced susceptibility to antimicrobials, associated with treatment failure, is increasing. • There is paucity of new antimicrobials in clinical development for treatment of CDI.
Authors 4
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Leiden University · Leiden University Medical Center
Affiliation as printed
Leiden University Center for Infectious Diseases (LUCID), Leiden University Medical Center, Leiden, the Netherlands. Electronic address: w.k.smits@lumc.nl
Leiden University Center for Infectious Diseases (LUCID), Leiden University Medical Center, The Netherlands. Electronic address: w.k.smits@lumc.nl
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Affiliation as printed
University of Houston College of Pharmacy, Houston, TX, USA
University of Houston College of Pharmacy, Houston TX, USA
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The University of Western Australia · Queen Elizabeth II Medical Centre · Pathwest Laboratory Medicine
Affiliation as printed
School of Biomedical Sciences, The University of Western Australia and Department of Microbiology, PathWest Laboratory Medicine (EA), Queen Elizabeth II Medical Centre, Nedlands, 6009, Western Australia, Australia
School of Biomedical Sciences, The University of Western Australia and Department of Microbiology, PathWest Laboratory Medicine (EA), Queen Elizabeth II Medical Centre, Nedlands 6009, Western Australia
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Affiliation as printed
Loyola University Chicago (Emeritus), Hines VA Hospital Research Service, Chicago, IL, USA
Loyola University Chicago (Emeritus), Hines VA Hospital Research Service, Chicago IL, USA
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