Serial quantitative optical coherence tomography for luminal volume changes following either paclitaxel or sirolimus coated balloon in de novo small coronary artery lesions

Cardiovascular revascularization medicine, vol. 81, pp. 62–67

Abstract

BACKGROUND: Drug coated balloons (DCB) are a treatment option for lesions in small coronary arteries, with treatment using paclitaxel coated balloons (PCB) associated with less angiographic late lumen loss than sirolimus coated balloons (SCB). METHODS: ) was defined as the post-procedural lumen volume - lumen volume at 6 months. RESULTS: in the SCB and PCB group, respectively (SCB vs PCB, p = 0.06). A trend for interaction between SCB and PCB was observed in the relationship between dissection volume and LLVL (SCB: LLVL = 1.28 ∗ dissection volume + 7.42, p = 0.37; PCB: LLVL = -2.84 ∗ dissection volume + 4.51, p = 0.12; p for interaction = 0.07). CONCLUSION: In de novo lesions of small coronary arteries, treatment with an SCB lead to a significant decrease in lumen volume at 6-months compared to post-procedure, with no significant change observed after treatment with a PCB.

Authors 11

1. Akihiro Tobe

   Ollscoil na Gaillimhe – University of Galway

   Affiliation as printed

   Department of Cardiology, School of Medicine, University of Galway, Galway, Ireland

2. Patrick W.J.C. Serruys

   Ollscoil na Gaillimhe – University of Galway

   Affiliation as printed

   Department of Cardiology, School of Medicine, University of Galway, Galway, Ireland. Electronic address: patrick.w.j.c.serruys@gmail.com

3. Kotaro Miyashita

   Ollscoil na Gaillimhe – University of Galway

   Affiliation as printed

   Department of Cardiology, School of Medicine, University of Galway, Galway, Ireland

4. Asahi Oshima

   Ollscoil na Gaillimhe – University of Galway

   Affiliation as printed

   Department of Cardiology, School of Medicine, University of Galway, Galway, Ireland

5. Pruthvi Chenniganahosahalli Revaiah

   Ollscoil na Gaillimhe – University of Galway

   Affiliation as printed

   Department of Cardiology, School of Medicine, University of Galway, Galway, Ireland

6. Tsung-Ying Tsai

   Ollscoil na Gaillimhe – University of Galway

   Affiliation as printed

   Department of Cardiology, School of Medicine, University of Galway, Galway, Ireland

7. Jouke Dijkstra Aachen

   Leiden University Medical Center

   Affiliation as printed

   Leiden University Medical Center (LUMC), Leiden, Netherlands

8. Scot Garg

   University of Lancashire · Royal Blackburn Teaching Hospital

   Affiliation as printed

   Department of Cardiology, Royal Blackburn Hospital, Blackburn, United Kingdom; School of Medicine, University of Central Lancashire, Preston, United Kingdom

9. Angela McInerney

   University Hospital Galway

   Affiliation as printed

   Cardiology Department, Galway University Hospital, Galway, Ireland

10. Yoshinobu Onuma

    Ollscoil na Gaillimhe – University of Galway · University Hospital Galway

    Affiliation as printed

    Department of Cardiology, School of Medicine, University of Galway, Galway, Ireland; Cardiology Department, Galway University Hospital, Galway, Ireland

11. Faisal Sharif

    Ollscoil na Gaillimhe – University of Galway · University Hospital Galway

    Affiliation as printed

    Department of Cardiology, School of Medicine, University of Galway, Galway, Ireland; Cardiology Department, Galway University Hospital, Galway, Ireland; Department of Cardiology, Saolta Group, Galway University Hospital Health Service Executive and University of Galway, Galway, Ireland; CÚRAM Research Ireland Centre for Medical Devices, Ireland