The interplay between brain and behavior during development: A multisite effort to generate and share simulated datasets

Scientific Data, vol. 12, pp. 473

Abstract

One of the challenges in the field of neuroimaging is that we often lack knowledge about the underlying truth and whether our methods can detect developmental changes. To address this gap, five research groups around the globe created simulated datasets embedded with their assumptions of the interplay between brain development, cognition, and behavior. Each group independently created the datasets, unaware of the approaches and assumptions made by the other groups. Each group simulated three datasets with the same variables, each with 10,000 participants over 7 longitudinal waves, ranging from 7 to 20 years-of-age. The independently created datasets include demographic data, brain derived variables along with behavior and cognition variables. These datasets and code that were used to generate the datasets can be downloaded and used by the research community to apply different longitudinal models to determine the underlying patterns and assumptions where the ground truth is known.

Authors 23

1. Neda Sadeghi

   National Institutes of Health · National Institute of Mental Health

   Affiliation as printed

   Section on Social and Cognitive Developmental Neuroscience, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland, USA

2. Isabelle F. van der Velpen

   National Institutes of Health · National Institute of Mental Health

   Affiliation as printed

   Section on Social and Cognitive Developmental Neuroscience, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland, USA

3. Bradley T. Baker

   Georgia Institute of Technology · Center for Translational Research in Neuroimaging and Data Science

   Affiliation as printed

   Tri-institutional Center for Translational Research in Neuroimaging and Data Science (TReNDS), Georgia State, Georgia Tech, Emory, Atlanta, Georgia, USA

4. Ishaan Batta

   Georgia Institute of Technology · Center for Translational Research in Neuroimaging and Data Science

   Affiliation as printed

   Tri-institutional Center for Translational Research in Neuroimaging and Data Science (TReNDS), Georgia State, Georgia Tech, Emory, Atlanta, Georgia, USA

5. Kyle Cahill

   Georgia Institute of Technology · Center for Translational Research in Neuroimaging and Data Science

   Affiliation as printed

   Tri-institutional Center for Translational Research in Neuroimaging and Data Science (TReNDS), Georgia State, Georgia Tech, Emory, Atlanta, Georgia, USA

6. Sarah Genon

   Forschungszentrum Jülich · Düsseldorf University Hospital · Heinrich Heine University Düsseldorf

   Affiliation as printed

   Institute of Neuroscience and Medicine (INM-7), Research Centre Jülich, Jülich, Germany

   Institute of Systems Neuroscience, Medical Faculty and University Hospital Düsseldorf, Heinrich-Heine University, Düsseldorf, Germany

7. Ethan Michael McCormick Aachen Methodology and Statistics Department Institute of Psychology, Leiden University

   Leiden University · University of Delaware

   Affiliation as printed

   Educational Statistics and Research Methods, School of Education, University of Delaware, Newark, USA

   Methodology and Statistics Department, Institute of Psychology, Leiden University, Leiden, The Netherlands

8. Lea C. Michel

   Radboud University Nijmegen · Radboud University Medical Center · Donders Institute for Brain, Cognition and Behaviour

   Affiliation as printed

   Donders Institute for Brain, Cognition and Behavior, Radboud University Medical Center, Nijmegen, The Netherlands

9. Dustin Moraczewski

   National Institutes of Health · National Institute of Mental Health

   Affiliation as printed

   Data Science and Sharing Team, National Institute of Mental Health, National Institutes Health, Bethesda, USA

10. Masoud Seraji

    Georgia Institute of Technology · Center for Translational Research in Neuroimaging and Data Science

    Affiliation as printed

    Tri-institutional Center for Translational Research in Neuroimaging and Data Science (TReNDS), Georgia State, Georgia Tech, Emory, Atlanta, Georgia, USA

11. Philip Shaw

    King's College London

    Affiliation as printed

    King's Maudsley Partnership for Child and Young People, King's College London, London, UK

12. Rogers F. Silva

    Georgia Institute of Technology · Center for Translational Research in Neuroimaging and Data Science

    Affiliation as printed

    Tri-institutional Center for Translational Research in Neuroimaging and Data Science (TReNDS), Georgia State, Georgia Tech, Emory, Atlanta, Georgia, USA

13. Najme Soleimani

    Georgia Institute of Technology · Center for Translational Research in Neuroimaging and Data Science

    Affiliation as printed

    Tri-institutional Center for Translational Research in Neuroimaging and Data Science (TReNDS), Georgia State, Georgia Tech, Emory, Atlanta, Georgia, USA

14. Emma Sprooten

    Radboud University Nijmegen · Radboud University Medical Center · Donders Institute for Brain, Cognition and Behaviour

    Affiliation as printed

    Donders Institute for Brain, Cognition and Behavior, Radboud University Medical Center, Nijmegen, The Netherlands

15. Øystein Sørensen

    University of Oslo

    Affiliation as printed

    Center for Lifespan Changes in Brain and Cognition, Department of Psychology, University of Oslo, Oslo, Norway

16. Adam G. Thomas

    National Institutes of Health · National Institute of Mental Health

    Affiliation as printed

    Data Science and Sharing Team, National Institute of Mental Health, National Institutes Health, Bethesda, USA

17. Audrey E. Thurm

    National Institutes of Health · National Institute of Mental Health

    Affiliation as printed

    Neurodevelopmental and Behavioral Phenotyping Service, National Institute of Mental Health, National Institutes of Health, Bethesda, USA

18. Zixuan Zhou

    Beijing Normal University · Child Mind Institute

    Affiliation as printed

    Center for the Integrative Developmental Neuroscience, Child Mind Institute, New York, USA

    Developmental Population Neuroscience Research Center, IDG/McGovern Institute for Brain Research, Faculty of Psychology, Beijing Normal University, Beijing, China

19. Vince D. Calhoun

    Georgia Institute of Technology · Center for Translational Research in Neuroimaging and Data Science

    Affiliation as printed

    Tri-institutional Center for Translational Research in Neuroimaging and Data Science (TReNDS), Georgia State, Georgia Tech, Emory, Atlanta, Georgia, USA

20. Rogier Kievit

    Radboud University Nijmegen · Radboud University Medical Center · Donders Institute for Brain, Cognition and Behaviour

    Affiliation as printed

    Donders Institute for Brain, Cognition and Behavior, Radboud University Medical Center, Nijmegen, The Netherlands

21. Anna Plachti

    Forschungszentrum Jülich · Düsseldorf University Hospital · Heinrich Heine University Düsseldorf

    Affiliation as printed

    Institute of Neuroscience and Medicine (INM-7), Research Centre Jülich, Jülich, Germany

    Institute of Systems Neuroscience, Medical Faculty and University Hospital Düsseldorf, Heinrich-Heine University, Düsseldorf, Germany

22. Xi‐Nian Zuo

    Beijing Normal University

    Affiliation as printed

    Developmental Population Neuroscience Research Center, IDG/McGovern Institute for Brain Research, Faculty of Psychology, Beijing Normal University, Beijing, China

23. Tonya J.H. White corresponding

    National Institutes of Health · National Institute of Mental Health

    Affiliation as printed

    Section on Social and Cognitive Developmental Neuroscience, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland, USA. tonya.white@nih.gov

    Section on Social and Cognitive Developmental Neuroscience, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland, USA