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Adopting a complex systems approach to functional ageing: bridging the gap between gerontological theory and empirical research

The Lancet Healthy Longevity, vol. 6, pp. 100673

Abstract

Functional ageing, related to but distinct from biological and environmental systems, is defined as the changes in physical, psychological, cognitive, and social functioning, as well as behavioural factors of individuals as they age. In this Personal View, we propose that a complex systems perspective to functional ageing can show how outcomes such as quality of life and longevity, and success in prevention and treatment, emerge from dynamic interactions among these domains, rather than from single causes. We support this view in three ways. First, we explain how three key principles of complex systems science-namely, resilience, non-linearity, and heterogeneity-apply to functional ageing. Second, we show how established gerontological theories and geriatric models align with these principles. Third, we illustrate the use of novel methodological tools available from complex systems science for studying functional ageing. Finally, we offer a glossary of key concepts and recommendations for researchers to adopt this perspective in future studies on functional ageing.

Authors 4

  1. Almar A. L. Kok corresponding

    Vrije Universiteit Amsterdam · Amsterdam University Medical Centers · Amsterdam Public Health

    Affiliation as printed

    Department of Epidemiology and Data Science, Amsterdam University Medical Centers, Vrije Universiteit Amsterdam, Amsterdam, Netherlands; Department of Psychiatry, Amsterdam University Medical Centers, Vrije Universiteit Amsterdam, Amsterdam, Netherlands; Amsterdam Public Health, Aging & Later Life programme, Amsterdam, Netherlands. Electronic address: a.kok1@amsterdamumc.nl

  2. Vrije Universiteit Amsterdam · Amsterdam University Medical Centers · Amsterdam Public Health

    Affiliation as printed

    Department of Epidemiology and Data Science, Amsterdam University Medical Centers, Vrije Universiteit Amsterdam, Amsterdam, Netherlands; Amsterdam Public Health, Aging & Later Life programme, Amsterdam, Netherlands; Department of Sociology, Vrije Universiteit Amsterdam, Amsterdam, Netherlands

  3. Leiden University Medical Center

    Affiliation as printed

    Department of Psychiatry, Leiden University Medical Center, Leiden, Netherlands

  4. Vrije Universiteit Amsterdam · Amsterdam University Medical Centers · Amsterdam UMC Location Vrije Universiteit Amsterdam · Amsterdam Public Health

    Affiliation as printed

    Department of Epidemiology and Data Science, Amsterdam University Medical Centers, Vrije Universiteit Amsterdam, Amsterdam, Netherlands; Amsterdam Public Health, Aging & Later Life programme, Amsterdam, Netherlands

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References 98