Nanosized core–shell bio-hybrid microgels and their internal structure

Nanoscale, vol. 17, pp. 4570–4577

Abstract

'-bis(acryloyl)cystamine, which provides visual insight into core and shell compartmentalization. The results demonstrate core polymer interpenetration into the shell without compromising its original structure, and additionally allow us to determine the size- and hydrophobicity dependent accessibility of the microgel core. This, offering new perspectives on the internal architecture of core-shell microgels, contributes to the in-depth understanding of their complex behavior, potentially guiding the rational design of new microgel drug delivery systems, taking into account the complex interplay of polarity, size and charge of guest molecules.

Authors 7

1. Pia Lenßen Aachen Institute of Physical Chemistry

   RWTH Aachen University

   Affiliation as printed

   Institute of Physical Chemistry, RWTH Aachen University, Landoltweg 2, 52074 Aachen, Germany

2. Rebecca Hengsbach Aachen Institute of Inorganic Chemistry

   RWTH Aachen University

   Affiliation as printed

   Institute of Inorganic Chemistry, RWTH Aachen University, Landoltweg 1a, 52074 Aachen, Germany

3. Anne Frommelius Aachen Institute of Inorganic Chemistry

   RWTH Aachen University

   Affiliation as printed

   Institute of Inorganic Chemistry, RWTH Aachen University, Landoltweg 1a, 52074 Aachen, Germany

4. Samira Cammeraat Aachen Institute of Physical Chemistry

   RWTH Aachen University

   Affiliation as printed

   Institute of Physical Chemistry, RWTH Aachen University, Landoltweg 2, 52074 Aachen, Germany

5. Koen Linssen Aachen Institute of Physical Chemistry

   RWTH Aachen University

   Affiliation as printed

   Institute of Physical Chemistry, RWTH Aachen University, Landoltweg 2, 52074 Aachen, Germany

6. Ulrich Simon Aachen Institute of Inorganic Chemistry

   RWTH Aachen University

   Affiliation as printed

   Institute of Inorganic Chemistry, RWTH Aachen University, Landoltweg 1a, 52074 Aachen, Germany

7. Dominik Wöll corresponding Aachen Institute of Physical Chemistry

   RWTH Aachen University

   Affiliation as printed

   Institute of Physical Chemistry, RWTH Aachen University, Landoltweg 2, 52074 Aachen, Germany