37 Post-transplantation management

Abstracts, pp. A22

Abstract

Systemic lupus erythematosus (SLE) is a complex autoimmune disorder that frequently involves the kidneys and can ultimately lead to renal replacement therapy or kidney transplantation for severe cases. Lifelong prevalence of end-stage kidney disease (ESKD) in SLE patients is 10–15%. 1 Therefore, although SLE is a rare disease, managing lupus patients after a kidney transplantation is even more rare and presents with its unique challenges. In this presentation I will address general aspects of care after kidney transplantation and then focus on SLE disease recurrence, graft rejection and complications from immunosuppressive therapy.Reference Hocaoğlu M, Valenzuela-Almada MO, Dabit JY, et al. Incidence, prevalence, and mortality of lupus nephritis: a population-based study over four decades using the lupus midwest network. Arthritis Rheumatol. 2023;75(4):567–73. doi: 10.1002/art.42375.Learning Objectives At the end of this presentation participants will be able to:Explain the impact of SLE on kidney function and the potential need for kidney transplantationDiscuss the risks and challenges associated with SLE recurrence after kidney transplantationExplain the potential complications associated with immunosuppressive therapy used after transplantation

Authors 1

1. Y K Onno Teng corresponding Aachen

   Leiden University Medical Center

   Affiliation as printed

   Leiden University Medical Center, The Netherlands