A decision-making framework to maximise the evolutionary potential of populations - Genetic and genomic insights from the common midwife toad (Alytes obstetricans) at its range limits
Heredity, vol. 133, pp. 249–261
Abstract
Anthropogenic habitat modification and climate change are fundamental drivers of biodiversity declines, reducing the evolutionary potential of species, particularly at their distributional limits. Supportive breeding or reintroductions of individuals are often made to replenish declining populations, sometimes informed by genetic analysis. However, most approaches utilised (i.e. single locus markers) do not have the resolution to account for local adaptation to environmental conditions, a crucial aspect to consider when selecting donor and recipient populations. Here, we incorporate genetic (microsatellite) and genome-wide SNP (ddRAD-seq) markers, accounting for both neutral and putative adaptive genetic diversity, to inform the conservation management of the threatened common midwife toad, Alytes obstetricans at the northern and eastern edges of its range in Europe. We find geographically structured populations (n = 4), weak genetic differentiation and fairly consistent levels of genetic diversity across localities (observed heterozygosity and allelic richness). Categorising individuals based on putatively adaptive regions of the genome showed that the majority of localities are not strongly locally adapted. However, several localities present high numbers of private alleles in tandem with local adaptation to warmer conditions and rough topography. Combining genetic diversity and local adaptations with estimates of migration rates, we develop a decision-making framework for selecting donor and recipient populations which maximises the geographic dispersal of neutral and putatively adaptive genetic diversity. Our framework is generally applicable to any species, but especially to amphibians, so armed with this information, conservationists may avoid the reintroduction of unsuitable/maladapted individuals to new sites and increase the evolutionary potential of populations within species.
Authors 6
-
Naturalis Biodiversity Center · German Centre for Integrative Biodiversity Research · Wageningen University & Research · Leipzig University
Affiliation as printed
Animal Breeding and Genomics, Wageningen University & Research, Droevendaalsesteeg 1, 6708 PB, Wageningen, The Netherlands. c.d.barratt@gmail.com
German Centre for Integrative Biodiversity Research (iDiv) Halle-Jena-Leipzig, Puschstrasse 4, 04103, Leipzig, Germany. c.d.barratt@gmail.com
Naturalis Biodiversity Center, Darwinweg 2, 2333 CR, Leiden, The Netherlands. c.d.barratt@gmail.com
University of Leipzig, Ritterstrasse 26, 04109, Leipzig, Germany. c.d.barratt@gmail.com
German Centre for Integrative Biodiversity Research (iDiv) Halle-Jena-Leipzig, Puschstrasse 4, 04103, Leipzig, Germany
-
Affiliation as printed
University of Leipzig, Institute of Biology, Molecular Evolution and Systematics of Animals, Talstrasse 33, 04103, Leipzig, Germany
-
Affiliation as printed
University of Leipzig, Institute of Biology, Molecular Evolution and Systematics of Animals, Talstrasse 33, 04103, Leipzig, Germany
-
Nature And Biodiversity Conservation Union
Affiliation as printed
NABU (Nature and Biodiversity Conservation Union) Lower Saxony, Alleestrasse 36, 30167, Hannover, Germany
-
Nature And Biodiversity Conservation Union
Affiliation as printed
NABU (Nature and Biodiversity Conservation Union) Lower Saxony, Alleestrasse 36, 30167, Hannover, Germany
-
Sebastian Steinfartz corresponding
Affiliation as printed
University of Leipzig, Institute of Biology, Molecular Evolution and Systematics of Animals, Talstrasse 33, 04103, Leipzig, Germany. steinfartz@uni-leipzig.de
University of Leipzig, Institute of Biology, Molecular Evolution and Systematics of Animals, Talstrasse 33, 04103, Leipzig, Germany
Cited by 4 stored of 4
4 results
No patents citing this paper on Lens.org (checked 2026-10-11).