Structure–function relationship of phase-separated liposomes containing diacylglycerol analogues

Biomaterials Science, vol. 12, pp. 5023–5035

Abstract

In the present study, liposomes consisting of DSPC and DOaG molecular analogues were assessed for their phase-separated morphology (cryoTEM), stability (DLS) and in vivo biodistribution (targeting the brain endothelial cells of zebrafish embryos).

Authors 12

1. Panagiota Papadopoulou Aachen Department of Supramolecular and Biomaterials Chemistry Leiden Institute of Chemistry

   Leiden University

   Affiliation as printed

   Department of Supramolecular & Biomaterials Chemistry, Leiden Institute of Chemistry (LIC), Leiden University, P.O. Box 9502, 2300 RA Leiden, The Netherlands

2. Gabriela Arias‐Alpizar Aachen Division of BioTherapeutics, Leiden Academic Centre for Drug Research

   Leiden University

   Affiliation as printed

   Division of BioTherapeutics, Leiden Academic Centre for Drug Research, Leiden University, P.O. Box 9502, 2300 RA Leiden, The Netherlands

3. Pim Weeda Aachen Department of Supramolecular and Biomaterials Chemistry Leiden Institute of Chemistry

   Leiden University

   Affiliation as printed

   Department of Supramolecular & Biomaterials Chemistry, Leiden Institute of Chemistry (LIC), Leiden University, P.O. Box 9502, 2300 RA Leiden, The Netherlands

4. Thijs Poppe Aachen Department of Supramolecular and Biomaterials Chemistry Leiden Institute of Chemistry

   Leiden University

   Affiliation as printed

   Department of Supramolecular & Biomaterials Chemistry, Leiden Institute of Chemistry (LIC), Leiden University, P.O. Box 9502, 2300 RA Leiden, The Netherlands

5. Niels van Klaveren Aachen Department of Supramolecular and Biomaterials Chemistry Leiden Institute of Chemistry

   Leiden University

   Affiliation as printed

   Department of Supramolecular & Biomaterials Chemistry, Leiden Institute of Chemistry (LIC), Leiden University, P.O. Box 9502, 2300 RA Leiden, The Netherlands

6. Tomas Slíva Aachen Department of Supramolecular and Biomaterials Chemistry Leiden Institute of Chemistry

   Leiden University

   Affiliation as printed

   Department of Supramolecular & Biomaterials Chemistry, Leiden Institute of Chemistry (LIC), Leiden University, P.O. Box 9502, 2300 RA Leiden, The Netherlands

7. Dennis Aschmann Aachen Department of Supramolecular and Biomaterials Chemistry Leiden Institute of Chemistry

   Leiden University

   Affiliation as printed

   Department of Supramolecular & Biomaterials Chemistry, Leiden Institute of Chemistry (LIC), Leiden University, P.O. Box 9502, 2300 RA Leiden, The Netherlands

8. Winant L. van Os Aachen Department of Supramolecular and Biomaterials Chemistry Leiden Institute of Chemistry

   Leiden University

   Affiliation as printed

   Department of Supramolecular & Biomaterials Chemistry, Leiden Institute of Chemistry (LIC), Leiden University, P.O. Box 9502, 2300 RA Leiden, The Netherlands

9. Mohammad‐Amin Moradi

   Eindhoven University of Technology

   Affiliation as printed

   Materials and Interface Chemistry, Department of Chemical Engineering and Chemistry, Eindhoven University of Technology, P.O. Box 513, 5600 MB Eindhoven, The Netherlands

10. Nico A. J. M. Sommerdijk

    Radboud University Nijmegen · Radboud University Medical Center · Radboud Institute for Molecular Life Sciences

    Affiliation as printed

    Department of Biochemistry, Radboud Institute of Molecular Life Sciences, Radboud University Medical Center, Nijmegen, The Netherlands

    Electron Microscopy Center, Radboud Technology Center Microscopy, Radboud University Medical Center, Nijmegen, The Netherlands

11. Frederick Campbell Aachen Department of Supramolecular and Biomaterials Chemistry Leiden Institute of Chemistry

    Leiden University

    Affiliation as printed

    Department of Supramolecular & Biomaterials Chemistry, Leiden Institute of Chemistry (LIC), Leiden University, P.O. Box 9502, 2300 RA Leiden, The Netherlands

12. Alexander Kros corresponding Aachen Department of Supramolecular and Biomaterials Chemistry Leiden Institute of Chemistry

    Leiden University

    Affiliation as printed

    Department of Supramolecular & Biomaterials Chemistry, Leiden Institute of Chemistry (LIC), Leiden University, P.O. Box 9502, 2300 RA Leiden, The Netherlands