Selective inference for fMRI cluster-wise analysis, issues, and recommendations for critical vector selection: A comment on Blain et al.

Imaging Neuroscience, vol. 2

Abstract

Abstract Two permutation-based methods for simultaneous inference on the proportion of active voxels in cluster-wise brain imaging analysis have recently been published: Notip and pARI. Both rely on the definition of a critical vector of ordered p-values, chosen from a family of candidate vectors, but differ in how the family is defined: computed from randomization of external data for Notip and determined a priori for pARI. These procedures were compared to other proposals in the literature, but an extensive comparison between the two methods is missing due to their parallel publication. We provide such a comparison and find that pARI outperforms Notip if both methods are applied under their recommended settings. However, each method carries different advantages and drawbacks.

Authors 4

1. Angela Andreella corresponding

   Ca' Foscari University of Venice

   Affiliation as printed

   Department of Economics, Ca’ Foscari University of Venice, Venice, Italy

2. Anna Vesely

   University of Bologna

   Affiliation as printed

   Department of Statistical Sciences, University of Bologna, Bologna, Italy

3. Wouter D. Weeda Aachen Department of Psychology, Leiden University

   Leiden University

   Affiliation as printed

   Department of Psychology, Leiden University, Leiden, The Netherlands

4. Jelle J. Goeman Aachen Department of Biomedical Data Sciences

   Leiden University Medical Center

   Affiliation as printed

   Department of Biomedical Data Sciences, Leiden University Medical Center, Leiden, The Netherlands