Processed data used for spatial analysis of DMD mouse models

Zenodo (CERN European Organization for Nuclear Research)

Abstract

This repository contains seurat objects and .H5AD files that were used in the analysis described in the paper titled "Spatial transcriptomics reveal markers of histopathological changes in Duchenne muscular dystrophy mouse models" Authors: L.G.M. Heezen, T. Abdelaal, M. van Putten, A. Aartsma-Rus, A. Mahfouz and P. Spitali It contains datafiles obtained from spatial transcriptomics (Visium, 10x Genomics) experiments on skeletal muscle samples from two wildtypes: C57BL10 and DBA/2J and two DMD mouse models: mdx and D2-mdx. All ten weeks old male mice, 10micron thick sections of the quadriceps.

Authors 2

1. LGM Heezen Aachen

   Leiden University Medical Center

   Affiliation as printed

   LUMC

2. Tamim Abdelaal

   Delft University of Technology

   Affiliation as printed

   LUMC, TU Delft